公开(公告)号：US06641591B1

公开(公告)日：2003-11-04

申请号：US09648025

申请日：2000-08-25

申请人： John H. Shadduck

发明人： John H. Shadduck

IPC分类号： A61B1750

CPC分类号： A61B17/545 ,  A61B17/50 ,  A61B17/54 ,  A61B2017/00761 ,  A61B2017/320004 ,  A61B2217/005 ,  A61B2217/007 ,  A61M1/0064 ,  A61M35/00

摘要： An instrument and technique for the removal of epidermal layers in a controlled manner utilizing a hand-held instrument with a working end that (i) a vacuum aspiration system, (ii) a source for delivery of a sterile fluids or pharmacological agents to the skin; and (iii) a skin interface surface in the working end that has specially shape structure for abrading surface layers of the patient's epidermis as the working end is moved over the patient's skin while at the same time causing rapid penetration of the fluids into the skin for therapeutic purposes. Movement of the working end across the skin causes abrasion of the surface layers in a path over the patient's skin. The method of the invention may be used in a periodic treatment for the removal of superficial skin layers that enhances the synthesis of dermal collagen aggregates by inducing the body's natural wound healing response. The method of the invention creates more normal dermal architectures in skin with limited depths of skin removal by the series of superficial treatments that may be comparable to the extent of neocollagenesis caused by a deep skin removal treatment (e.g., CO2 laser skin removal).

摘要翻译： 一种利用具有工作端的手持式仪器以受控方式去除表皮层的仪器和技术，该工具包括（i）真空抽吸系统，（ii）用于将无菌流体或药物剂递送至皮肤的源 ; 和（iii）工作端中的皮肤界面表面，其具有特殊的形状结构，用于当工作端移动到患者皮肤上同时使流体快速渗透到皮肤中时，用于研磨患者表皮的表面层 治疗目的。 穿过皮肤的工作端的移动导致患者皮肤上的路径中的表面层的磨损。 本发明的方法可用于周期性治疗以通过诱导人体的自然伤口愈合反应来去除表皮层，从而增强真皮胶原聚集体的合成。 本发明的方法在皮肤中产生更正常的皮肤结构，通过一系列表皮处理有限的皮肤去除深度，其可以与由深层皮肤去除处理（例如，CO2激光皮肤去除）引起的新胶原形成的程度相当。

公开(公告)号：US06503251B1

公开(公告)日：2003-01-07

申请号：US09694417

申请日：2000-10-23

申请人： John H. Shadduck

发明人： John H. Shadduck

IPC分类号： A61B1756

CPC分类号： A61F2/0811 ,  A61B17/0401 ,  A61B17/8685 ,  A61B2017/00004 ,  A61B2017/0409 ,  A61B2017/044 ,  A61B2017/0445 ,  A61B2017/0458 ,  A61F2/0805 ,  A61F2002/0858 ,  A61F2002/087

摘要： A surgical fixation screw that can be driven with significantly reduced torque thus allowing for theaded fixation bodies to be made substantially of bioabsorbable materials. The novel fixation body, also called an offset helix fixation body, extends along a first (central) axis. The fixation body comprises first and second helically-mating members that mate along a constant-lead helical interface that extends about a second (non-central) axis. The second axis is angularly offset from the first axis of the fixation body from about 1° to 20°. Alternatively, the second axis is parallel to, but laterally offset from, the first axis. Thus, the first and second members of the fixation body can travel helically relative to one another about the helical mating interface between a first insertion configuration and a second anchor configuration. In the insertion configuration, the screw's outer periphery has a first (lesser) transverse sectional dimension to allow reduced torque in helically driving the screw into a space in a bone. After being driven into a space or bore, the first and second members then can be moved helically relative to one another about the helical mating interface to an anchor configuration in which the screws outer periphery is expanded radially outward to provide a second (greater) transverse sectional dimension for securing the fixation body in the space or bore.

摘要翻译： 可以以显着减小的扭矩驱动的手术固定螺钉，从而允许使阴影的固定体基本上由生物可吸收材料制成。 新颖的固定体，也称为偏移螺旋固定体，沿着第一（中心）轴延伸。 固定体包括第一和第二螺旋配合构件，其沿着绕第二（非中心）轴线延伸的恒定引线螺旋界面配合。 第二轴线从固定体的第一轴线角度偏移约1°至20°。 或者，第二轴线与第一轴线平行但横向偏移。 因此，固定体的第一和第二构件可以围绕第一插入构型和第二锚定构型之间的螺旋配合界面相对于彼此螺旋地行进。 在插入构造中，螺钉的外周边具有第一（较小的）横截面尺寸，以允许减小将螺钉螺旋驱动到骨骼空间中的扭矩。 在被驱动到空间或孔中之后，第一和第二构件然后可以围绕螺旋配合界面相对于彼此螺旋地移动到锚定构造，其中螺钉外周边径向向外延伸以提供第二（较大）横向 用于将固定体固定在空间或孔中的截面尺寸。

公开(公告)号：US06500176B1

公开(公告)日：2002-12-31

申请号：US09694233

申请日：2000-10-23

申请人： Csaba Truckai ,  John H. Shadduck

发明人： Csaba Truckai ,  John H. Shadduck

IPC分类号： A61B1818

CPC分类号： A61B18/1445 ,  A61B2018/00601 ,  A61B2018/0063 ,  A61B2018/00702 ,  A61B2018/00791 ,  A61B2018/00875

摘要： An electrosurgical medical device and technique for creating thermal welds in the transected margin of engaged tissue. The working end of the invention carries a bi-polar electrode arrangement that provides a novel type of Rf current flow for tissue welding described as an subfascial-to-fascial (or medial-to-surface) bi-polar approach. The working end of the device carries an openable and closable jaw assembly with paired first and second jaws for engaging tissue. The paired jaws have an axial channel for receiving a sliding (blade) member for transecting the captured tissue. The paired jaws carry electrode surfaces having a common polarity so that Rf current will not flow directly between the jaws which engage the surface or fascial tissue layers. The transecting member, when fully extended after transecting the captured tissue, carries an elongate electrode of an opposing polarity that engages the medial or subfascial layers of the tissue. Thus, bi-polar current is directed to flow from the transecting member electrode that engages medial tissue layers to both jaws that engage opposing surface tissue layers to create effective current densities in the medial tissue layers, even when transecting thick tissue volumes or vessels with thick non-uniform fascial layers.

摘要翻译： 一种用于在接合组织的横切边缘产生热焊缝的电外科医疗装置和技术。 本发明的工作端携带双极电极装置，其提供用于组织焊接的新型的Rf电流流动，其被描述为子筋 - 筋膜（或内向 - 面）双极方法。 该装置的工作端装有一个可打开和关闭的钳口组件，具有成对的第一和第二钳口，用于接合组织。 成对的夹爪具有轴向通道，用于接收用于横切所捕获的组织的滑动（叶片）构件。 成对的钳口携带具有共同极性的电极表面，使得Rf电流将不会直接流到接合表面或筋膜组织层的钳口之间。 横切构件在横切被捕获的组织之后完全延伸时，携带相对极性的细长电极，其接合组织的内侧或筋膜下层。 因此，双极电流被引导到从接合内侧组织层的横截面部件电极到与接合相对表面组织层的两个钳口的流动，以便在内侧组织层中形成有效的电流密度，即使当横截面厚的组织体积或具有厚的 不均匀的筋膜层。

公开(公告)号：US06485436B1

公开(公告)日：2002-11-26

申请号：US09637463

申请日：2000-08-10

申请人： Csaba Truckai ,  Bruno Strul ,  John H. Shadduck

发明人： Csaba Truckai ,  Bruno Strul ,  John H. Shadduck

IPC分类号： A61B500

CPC分类号： A61B10/0275 ,  A61B10/0283 ,  A61B18/1477 ,  A61B2010/0225 ,  A61B2018/0063 ,  A61B2018/1425

摘要： An improved biopsy needle assembly for efficient removal of multiple biopsy cores from a single needle penetration. The needle apparatus comprises an elongate assembly of paired sleeves with an open notch in the wall of the outer sleeve for engaging a tissue volume in the bore of that sleeve. An inner sleeve or blade member with a sharp blade edge is moveable from a retracted position to an extended position to both (i) excise the tissue volume, and (ii) function as valve means to alter the open notch between an open position and a closed position. The invention provides a looped inflow-outflow passageway system for using high-pressure fluid flows to push or expel the excised tissue from the bore in working end where the excised tissue is captured. The looped passageway system is coupled to a remote pressurization source.

摘要翻译： 一种改进的活检针组件，用于从单针穿透有效地去除多个活检芯。 针装置包括成对的套筒的细长组件，其在外套筒的壁中具有开口的凹口，用于接合该套筒的孔中的组织体积。 具有锋利刀片边缘的内套筒或刀片构件可从缩回位置移动到延伸位置，以便（i）切除组织体积，和（ii）用作阀装置，以改变打开位置和打开位置之间的打开凹口 关闭位置。 本发明提供了一种循环的流入 - 流出通道系统，用于使用高压流体流在被切除的组织被捕获的工作端中从所述孔中推动或排出切除的组织。 环形通道系统联接到远程加压源。

公开(公告)号：US06306075B1

公开(公告)日：2001-10-23

申请号：US09473731

申请日：1999-12-27

申请人： John H. Shadduck

发明人： John H. Shadduck

IPC分类号： A61B1752

CPC分类号： A61F2/147 ,  A61B18/08 ,  A61F9/0079 ,  A61F2009/00872 ,  A61F2210/009 ,  A61N2/02

摘要： A system and technique called magnetoresonant induction of an intrastromal implant that is adapted for corneal re-shaping. The technique is utilized to correct mild to high hyperopia and presbyopia by steepening the anterior corneal curvature in a single treatment, or in periodic treatments over the lifetime of the patient. The system comprises a combination of components including (i) at least one implantable magnetoresonant intrastromal segment, and (ii) an oscillating magnetic field generator together with a dosimetry control system including at least one emitter body adapted for positioning proximate to the patient's eye and intrastromal implant. The system can deliver thermal effects to appropriate stromal lamellae by non-contact inductive heating of the implant which in turn contracts or compresses stromal collagen fibrils into a circumferenitial cinch about an anterior layer of the cornea and steepens the anterior corneal curvature. A dosimetry control system controls the power level and duration of exposure of the oscillating magnetic field(s) and may be combined with intraoperative corneal topography. The system can be adapted for non-contact energy delivery to selected locations in other body structures in the interior of a patient's body.

摘要翻译： 称为腔内植入物的磁共振诱导的系统和技术，适用于角膜重塑。 该技术用于通过在单次治疗中陡峭的前角膜曲率或在患者的一生中的定期治疗中来矫正轻度至高度的远视和老花眼。 该系统包括组件的组合，包括（i）至少一个可植入的磁共振腔内质膜段，和（ii）振荡磁场发生器以及剂量测定控制系统，该剂量测定系统包括至少一个发射体，其适合于靠近患者的眼睛定位和内分泌 注入。 该系统可以通过植入物的非接触感应加热将热效应传递到适当的基质片层，其进而将基质胶原原纤维收缩或压缩成围绕角膜前层的周围环状，并使前角膜曲率变得更深。 剂量测量控制系统控制振荡磁场的功率水平和暴露持续时间，并且可以与术中角膜形态结合。 该系统可以适用于将非接触能量递送到患者身体内部的其他身体结构中的选定位置。

公开(公告)号：US6053909A

公开(公告)日：2000-04-25

申请号：US49711

申请日：1998-03-27

申请人： John H. Shadduck

发明人： John H. Shadduck

IPC分类号： A61B18/14 ,  A61B18/22 ,  A61H5/06

CPC分类号： A61B18/22 ,  A61B18/148

摘要： An Rf energy applicator with a working end that carries a bi-polar Rf electrode system for creating a Rf-tissue interaction or ionothermal effect in subsurface tissue (a first ionothermal system) which effect is focused by concurrent actuation of a photonic tissue-sensitizing system or photoconductance system (a second ionothermal system). The photonic energy system is adapted to create a "lens electrode" in subsurface tissue that enhances the targeted tissue's conductance of Rf current which serves as a means of focusing Rf ionothermal effects at a subsurface level. A dosimetry control system is provided that controls the dose and timing of Rf energy delivery as well as the dosimetry of photonic energy delivery. The ionothermal applicator has a handle portion coupled a tubular extending member. The distal termination of the probe has at least one pair of opposing conductive electrodes in a spaced relationship around a perimeter of the distal termination of the extending member. A remote Rf source (or generator) is connected to the device for delivering bi-polar Rf energy to the paired electrodes. An optical fiber (or fiber optic bundle) is provided in a central channel of the extending member which is capable of delivering a photonic (light) beam from a light source, such as a pulsed laser (or continuous wave (CW) diode laser).

摘要翻译： 具有工作端的Rf能量施加器，其携带用于在地下组织（第一离子温度系统）中产生Rf-组织相互作用或离子温度效应的双极性Rf电极系统，该效应通过光子组织增感系统 或光电导系统（第二离子温度系统）。 光子能量系统适于在地下组织中产生“透镜电极”，从而增强目标组织的Rf电流，其作为在地下水平聚焦Rf离子温度效应的手段。 提供了一种剂量测定控制系统，其控制Rf能量递送的剂量和时间以及光子能量递送的剂量测定。 离子热施加器具有联接管状延伸构件的手柄部分。 探针的远端终端具有围绕延伸构件的远端终端的周边间隔开的至少一对相对的导电电极。 远程Rf源（或发生器）连接到设备，用于将双极Rf能量传递到成对的电极。 在延伸构件的中心通道中提供光纤（或光纤束），其能够从诸如脉冲激光（或连续波（CW）二极管激光器）的光源传送光子（光）束， 。

公开(公告)号：US06006756A

公开(公告)日：1999-12-28

申请号：US128056

申请日：1998-08-03

申请人： John H. Shadduck

发明人： John H. Shadduck

IPC分类号： A61B17/52 ,  A61F13/00 ,  A61M37/00 ,  A61N1/08 ,  A61B17/36

CPC分类号： A61F2/147 ,  A61B18/08 ,  A61F2009/00872 ,  A61F2210/009 ,  A61F9/0079 ,  A61N2/02

摘要： A system and technique called magnetoresonant induction of an intrastromal implant that is adapted for corneal re-shaping. The technique is utilized to correct mild to high hyperopia and presbyopia by steepening the anterior corneal curvature in a single treatment, or in periodic treatments over the lifetime of the patient. The system comprises a combination of components including (i) at least one implantable magnetoresonant intrastromal segment, and (ii) an oscillating magnetic field generator together with a dosimetry control system including at least one emitter body adapted for positioning proximate to the patient's eye and intrastromal implant. The system can deliver thermal effects to appropriate stromal lamellae by non-contact inductive heating of the implant which in turn contracts or compresses stromal collagen fibrils into a circumferential cinch about an anterior layer of the cornea and steepens the anterior corneal curvature. A dosimetry control system controls the power level and duration of exposure of the oscillating magnetic field(s) and may be combined with intraoperative corneal topography.

摘要翻译： 称为腔内植入物的磁共振诱导的系统和技术，适用于角膜重塑。 该技术用于通过在单次治疗中陡峭的前角膜曲率或在患者的一生中的定期治疗中来矫正轻度至高度的远视和老花眼。 该系统包括组件的组合，包括（i）至少一个可植入的磁共振腔内质膜段，和（ii）振荡磁场发生器以及剂量测定控制系统，该剂量测定系统包括至少一个发射体，其适合于靠近患者的眼睛定位和内分泌 注入。 该系统可以通过植入物的非接触感应加热将热效应传递给适当的基质薄片，这又将基质胶原原纤维收缩或压缩成围绕角膜前层的周围束缚，并使前角膜曲率变得更陡峭。 剂量测量控制系统控制振荡磁场的功率水平和暴露持续时间，并且可以与术中角膜形态结合。

公开(公告)号：US11832704B2

公开(公告)日：2023-12-05

申请号：US18049411

申请日：2022-10-25

申请人： John H. Shadduck

发明人： John H. Shadduck

IPC分类号： A45D33/34 ,  A45D40/26 ,  A45D34/04

CPC分类号： A45D33/34 ,  A45D34/04 ,  A45D40/26 ,  A45D2200/1009

摘要： Cosmetic applicators, blenders and aids, and more particularly to a resilient blender that includes an open-cell memory foam surface component that is easily cleanable or disposable in combination with a resilient core component. Further, the core component of the system includes a spring structure for greatly accelerating the rebound of the blender surface from a compressed state to a repose memory or de-compressed state.

公开(公告)号：US11510474B1

公开(公告)日：2022-11-29

申请号：US17302528

申请日：2021-05-05

申请人： John H. Shadduck

发明人： John H. Shadduck

IPC分类号： A45D33/34 ,  A45D40/26 ,  A45D34/04

摘要： Cosmetic applicators, blenders and aids, and more particularly to a resilient blender that includes an open-cell memory foam surface component that is easily cleanable or disposable in combination with a resilient core component. Further, the core component of the system includes a spring structure for greatly accelerating the rebound of the blender surface from a compressed state to a repose memory or de-compressed state.

公开(公告)号：US11122879B1

公开(公告)日：2021-09-21

申请号：US17333689

申请日：2021-05-28

申请人： John H. Shadduck

发明人： Amelia Tammel ,  John H. Shadduck

IPC分类号： A45D33/34 ,  A45D34/04 ,  A45D40/26

摘要： Hygienic cosmetic applicators, blenders and aids, and more particularly to a soft, resilient blender system that includes an open-cell memory foam surface component that is easily cleanable or disposable in combination with a core resilient component that is fluid impermeable. Hygienic cosmetic applicators, blenders and aids including a core component with one or more spring elements for greatly accelerating the rebound of the blender surface from a compressed state to a repose memory state.