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    LAG3 Binding Peptides
    82.
    发明申请
    LAG3 Binding Peptides 审中-公开

    公开(公告)号：US20200369766A1

    公开(公告)日：2020-11-26

    申请号：US16879884

    申请日：2020-05-21

    Applicant: Leidos, Inc.

    Inventor： Gabriel M. Gutierrez ,  Vinayaka Kotraiah ,  Timothy W. Phares ,  James Pannucci ,  Marc Mansour

    IPC: C07K16/28 ,  C12N15/11 ,  A61K39/395 ,  A61K45/06

    Abstract: This disclosure provides peptides which bind to LAG3 and can be used to block the interaction of LAG 3 with other molecules such as MHC-II, FGL1, and α-synuclein. These peptides can be used for various therapeutic purposes, such as inhibiting the progression of a hyperproliferative disorder, including cancer, or inhibiting the progression of a synucleinopathy, inhibiting the progression of sepsis, inhibiting the progression of an infectious disease, and enhancing a response to a vaccine.

    Motion extended array synthesis for use in high resolution imaging applications
    83.
    发明授权
    Motion extended array synthesis for use in high resolution imaging applications 有权

    公开(公告)号：US10823843B1

    公开(公告)日：2020-11-03

    申请号：US15789101

    申请日：2017-10-20

    Applicant: Leidos, Inc.

    Inventor： John R. Kendra

    IPC: G01S13/90 ,  G01S13/46 ,  G01S13/58 ,  G01S13/02

    Abstract: A process and systems for constructing arbitrarily large virtual arrays using two or more collection platforms (e.g. AUX and MOV systems) having differing velocity vectors. Referred to as Motion Extended Array Synthesis (MXAS), the resultant imaging system is comprised of the collection of baselines that are created between the two collection systems as a function of time. Because of the unequal velocity vectors, the process yields a continuum of baselines over some range, which constitutes an offset imaging system (OIS) in that the baselines engendered are similar to those for a real aperture of the same size as that swept out by the relative motion, but which are offset by some (potentially very large) distance.

    Acoustic Vector Sensor
    84.
    发明申请
    Acoustic Vector Sensor 审中-公开

    公开(公告)号：US20200257010A1

    公开(公告)日：2020-08-13

    申请号：US16847290

    申请日：2020-04-13

    Applicant: Leidos, Inc.

    Inventor： Brian Hamburg ,  Norman Gholson

    IPC: G01V1/18 ,  G01V1/38 ,  G01H3/12 ,  G01V1/00 ,  G01P5/02

    Abstract: An acoustic vector sensor (“AVS”) includes one or more sensitive elements arranged in an orthogonal configuration to provide high-sensitivity directional performance. The one more sensitive elements may be seismometers arranged in a pendulum-type configuration. The AVS further includes a hydrophone.

    Contact Imaging Sensor Head For Computed Radiography
    85.
    发明申请
    Contact Imaging Sensor Head For Computed Radiography 审中-公开

    公开(公告)号：US20200064282A1

    公开(公告)日：2020-02-27

    申请号：US16667298

    申请日：2019-10-29

    Applicant: Leidos, Inc.

    Inventor： Rex David Richardson ,  William L. Hicks ,  Mark Alan Peressini

    IPC: G01N23/22

    Abstract: A scan head design uses 1:1 (one-to-one) imaging micro-lens arrays to transfer the object plane X-ray image from a CR-plate onto a linear photosensor. The scan-head includes a housing having therein, an array of red light emitting diodes (LEDs), a red-absorbing filter, a microlens array, an infrared-filter, and a sensor. The housing faces the CR-plate and the scan-head is translated across the CR-plate to read out the X-ray image therein. The scan head is compact and provides for improved spatial resolution and reduced power requirements.

    Mechanism for automatic network formation and medium access coordination
    86.
    发明授权
    Mechanism for automatic network formation and medium access coordination 有权

    公开(公告)号：US10270665B2

    公开(公告)日：2019-04-23

    申请号：US15875302

    申请日：2018-01-19

    Applicant: Leidos, Inc.

    Inventor： Ana M. Cheng ,  Norbert J. Riviere

    IPC: H04L12/24 ,  H04W84/18 ,  H04W72/04

    Abstract: The invention provides a set of mechanisms by which a wireless mobile mesh node equipped with a directional antenna may self form and self adapt its steady-state communications schedule. A link establishment handshake is carried out over an ongoing subtemplate-based discovery scan. During time not reserved for steady-state communications with previously discovered neighbors, nodes continue to search for an establish links with new neighbors. Initial and subsequent bandwidth allocation protocols may be utilized to allow peer nodes to coordinate communication opportunities between the peer nodes without impacting or having knowledge about reservations for communications with other peers. The link establishment and initial bandwidth allocation protocols may be piggy-backed for readily establishing an initial steady-state schedule with a peer upon link establishment without impact on previous steady state reservations by other nodes or on ongoing link establishment attempts elsewhere.

    System and method for fusing chemical detectors
    87.
    发明授权
    System and method for fusing chemical detectors 有权

    公开(公告)号：US10249481B2

    公开(公告)日：2019-04-02

    申请号：US15190338

    申请日：2016-06-23

    Applicant: Leidos, Inc.

    Inventor： Charles Stephen Harden ,  Robert James Schafer

    IPC: H01J49/00 ,  H01J49/02 ,  G01N27/62

    Abstract: Two complementary approaches to the science of IMS technology, IMS and differential IMS (DIMS), are combined into a single instrument to provide improvements in interference rejection without sacrificing detection sensitivity. The technology is applicable to, inter alia, the analysis of trace quantities of toxic or otherwise dangerous organic chemical materials. The approach improves both sensitivity and specificity (interference rejection) of field detection instrumentation.

    Method and System For Multiple Carrier Resource Allocation in LTE-Advanced Networks
    88.
    发明申请
    Method and System For Multiple Carrier Resource Allocation in LTE-Advanced Networks 审中-公开

    公开(公告)号：US20190059025A1

    公开(公告)日：2019-02-21

    申请号：US16153968

    申请日：2018-10-08

    Applicant: Leidos, Inc.

    Inventor： Rebecca K. Harrington

    IPC: H04W28/24 ,  H04W4/00 ,  H04M15/00 ,  H04W4/24

    CPC classification number: H04W28/24 ,  H04M15/8044 ,  H04M15/805 ,  H04M15/8055 ,  H04W4/00 ,  H04W4/24

    Abstract: A process for selecting an optimal individual user solution including an optimal rate allocation and associated price for a predetermined bandwidth of cellular network resources includes application of an iterative process and selection from multiple proposed user solutions. The inputs to the iterative process include at least an initial user bid, an initial network rate allocation, a generated user utility function and the cost data. The user utility function includes multiple application user functions. Optimal solution selection includes comparing each multiple proposed user rate allocation with the initial network rate allocation for the user and selecting the closest multiple proposed user rate allocation to the initial network rate allocation. The process may be applied to aggregated cellular carrier scenarios.

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