公开(公告)号：US20240325210A1

公开(公告)日：2024-10-03

申请号：US18742096

申请日：2024-06-13

Applicant: Solventum Intellectual Properties Company

Inventor： Christopher Brian LOCKE ,  Justin Alexander LONG ,  Benjamin LOCKE ,  Benjamin A. PRATT ,  Thomas EDWARDS

IPC: A61F13/05 ,  A61F13/00 ,  A61M1/00

CPC classification number: A61F13/05 ,  A61M1/913 ,  A61F2013/00246 ,  A61M1/915 ,  A61M1/916

Abstract: An evaporative bridge dressing that may be used with negative-pressure treatment of tissue. The evaporative bridge dressing may have one or more fluid transfer layers comprised of high-density wicking material enclosed between layers of film having high moisture-vapor transfer rates to reduce liquid storage and minimize pressure drop.

公开(公告)号：US20240320382A1

公开(公告)日：2024-09-26

申请号：US18618192

申请日：2024-03-27

Applicant: SOLVENTUM INTELLECTUAL PROPERTIES COMPANY

Inventor： Jonathan D. Gandrud ,  Cameron M. Fabbri ,  Joseph C. Dingeldein ,  James D. Hansen ,  Benjamin D. Zimmer

IPC: G06F30/10 ,  A61C13/00 ,  A61C13/34 ,  G06T17/20

CPC classification number: G06F30/10 ,  A61C13/0004 ,  A61C13/34 ,  G06T17/20

Abstract: Techniques are described for automating the design of dental restoration appliances using machine learning models. An example computing device receives transform information associated with a current dental anatomy of a dental restoration patient, provides the transform information associated with the current dental anatomy of the dental restoration patient as input to a machine learning model trained with transform information indicating placement of a dental appliance component with respect to one or more teeth of corresponding dental anatomies, the dental appliance being used for dental restoration treatment for the one or more teeth, and executes the machine learning model using the input to produce placement information for the dental appliance component with respect to the current dental anatomy of the dental restoration patient.

公开(公告)号：US12097094B2

公开(公告)日：2024-09-24

申请号：US17242746

申请日：2021-04-28

Applicant: Solventum Intellectual Properties Company

Inventor： Jonathan Paul Jaeb ,  Richard Daniel John Coulthard ,  Timothy Mark Robinson ,  Christopher Brian Locke ,  Aidan Marcus Tout

IPC: A61F13/05 ,  A61F13/00 ,  A61M1/00

CPC classification number: A61F13/05 ,  A61F13/00063 ,  A61M1/74 ,  A61M1/78 ,  A61M1/784 ,  A61M1/915 ,  A61M1/962 ,  A61M1/985 ,  A61F2013/00174 ,  A61F2013/00412 ,  A61F2013/00536 ,  A61F2013/00544 ,  A61M1/912 ,  A61M1/964 ,  A61M1/966 ,  A61M2205/15 ,  A61M2205/7536

Abstract: A reduced pressure dressing for applying reduced pressure treatment to a tissue site includes an interface layer adapted to be positioned at the tissue site. An absorbent layer is in fluid communication with the interface layer to absorb liquid from at least one of the interface layer and the tissue site. A pump is in fluid communication with the absorbent layer to deliver a reduced pressure to the tissue site. A cover is positioned over the pump, the absorbent layer, and the interface layer to maintain the reduced pressure at the tissue site, and a liquid-air separator is positioned between the absorbent layer and the pump to inhibit liquid from entering the pump.

公开(公告)号：US20240300947A1

公开(公告)日：2024-09-12

申请号：US18665823

申请日：2024-05-16

Applicant: Solventum Intellectual Properties Company

Inventor： George W. Griesgraber ,  Bryon A. Merrill ,  Michael J. Rice

IPC: C07D471/04 ,  A61K31/4745 ,  A61P37/04

CPC classification number: C07D471/04 ,  A61K31/4745 ,  A61P37/04

Abstract: Imidazo[4,5-c]quinoline compounds having a substituent that is attached at the N-1 position by a branched group, single enantiomers of the compounds, pharmaceutical compositions containing the compounds, and methods of making the compounds are disclosed. Methods of use of the compounds as immune response modifiers, for inducing cytokine biosynthesis in humans and animals, and in the treatment of diseases including infectious and neoplastic diseases are also disclosed.

公开(公告)号：US12070377B2

公开(公告)日：2024-08-27

申请号：US17606516

申请日：2020-05-14

Applicant: Solventum Intellectual Properties Company

Inventor： Christopher Brian Locke

IPC: A61F13/05 ,  A61F13/00 ,  A61F13/02 ,  A61F13/0206 ,  A61M1/00

CPC classification number: A61F13/05 ,  A61F13/00055 ,  A61F13/0206 ,  A61F13/0289 ,  A61M1/912 ,  A61M1/915 ,  A61M1/985 ,  A61M1/966 ,  A61M1/982 ,  A61M2207/00

Abstract: An assembly for coupling a dressing to a tube connected to a pump includes a hydrophobic film layer comprising a perforation extending therethrough, an indicator coupled to a first side of the hydrophobic film layer and positioned proximate the perforation, a felted foam layer coupled to a second side of the hydrophobic film layer and fluidly communicable with the indicator via the perforation, and a connection pad coupled to the first side of the hydrophobic film layer and coupleable to the tube.

公开(公告)号：US12059319B2

公开(公告)日：2024-08-13

申请号：US17597599

申请日：2020-07-28

Applicant: Solventum Intellectual Properties Company

Inventor： Andreas J. Boehm ,  Marc Peuker ,  Paul J. Homnick ,  Bruce R. Broyles

IPC: A61C5/62 ,  A61C5/50 ,  A61C5/64 ,  A61M3/00 ,  A61M3/02

CPC classification number: A61C5/50 ,  A61C5/62 ,  A61C5/64 ,  A61M3/005 ,  A61M3/0201 ,  A61M3/0262

Abstract: A syringe assembly being assembled from a syringe for dispensing a dental or medical substance, and a protective cover. The protective cover has a geometrically determined, non-foldable tubular protective shaft. The syringe has a cartridge having an outlet for the substance. Further, the cartridge and the protective cover are assembled with the cartridge being received within the protective shaft. The syringe further comprises a dispensing tip that is connected to the outlet for dispensing the substance from the dispensing tip. A first seal is provided between the dispensing tip and the outlet, and a second seal is provided between the dispensing tip and the protective shaft.

公开(公告)号：US20240238069A1

公开(公告)日：2024-07-18

申请号：US18601953

申请日：2024-03-11

Applicant: Solventum Intellectual Properties Company

Inventor： David K. Cinader ,  Rainer Dittmann ,  Michael K. Domroese ,  Thomas K. Mueller ,  Dietmar Blees ,  Özcan Dönmez ,  Daniel D. Oberpertinger ,  Ralf M. Paehl ,  Shane C. Pedersen ,  Nicholas A. Stark ,  Michaela Urban

IPC: A61C7/14

CPC classification number: A61C7/146

Abstract: A method of making a transfer apparatus includes providing a physical mockup having a shape that corresponds to a positive shape of a patient's dental arch and one or more carrier assemblies that each include a crane body releasably connected to an orthodontic appliance. A transfer apparatus may be formed over the physical mockup, with the transfer tray representing a negative replica of at least a portion of the mockup. The transfer apparatus may be used to seat the appliance on a patient's dental arch, after which point the appliance can be separated from the crane body and bonded to the associated tooth.

公开(公告)号：US12036354B2

公开(公告)日：2024-07-16

申请号：US16855320

申请日：2020-04-22

Applicant: Solventum Intellectual Properties Company

Inventor： Ryan Conner ,  Dean Hu ,  Crystal Musante ,  Kenneth Wu

IPC: A61M1/00

CPC classification number: A61M1/984 ,  A61M1/67 ,  A61M1/78 ,  A61M1/815 ,  A61M1/86 ,  A61M1/912 ,  A61M1/918 ,  A61M1/96 ,  A61M1/982 ,  A61M1/74 ,  A61M1/882 ,  A61M2205/7536 ,  A61M2205/8281 ,  A61M2209/088

Abstract: Methods and devices for treatment of damaged tissue are disclosed, including treatment of wounds by employing non-electrically powered, reduced pressure therapy devices. Maintenance and control of the sub atmospheric pressure exerted may be provided by such devices while minimizing discomfort to the user. The devices may be configured to be worn inconspicuously underneath clothing.

公开(公告)号：US12027258B2

公开(公告)日：2024-07-02

申请号：US17653882

申请日：2022-03-08

Applicant: Solventum Intellectual Properties Company

Inventor： Larry D. Cousin

IPC: G16H40/20 ,  G16H10/60 ,  G16H50/20

CPC classification number: G16H40/20 ,  G16H10/60 ,  G16H50/20

Abstract: A computer implemented method includes obtaining a schema defining variables representing patient treatment experiences for one or more health conditions, obtaining data from historical patient treatment experiences, the data being arranged in accordance with the schema, training a machine learning system based on a training set of the data for a specified time-period, and generating a model from the trained machine learning system, the model being based on variables selected by the trained machine learning system to predict patient treatment experiences for the one or more health conditions.

公开(公告)号：US12024514B2

公开(公告)日：2024-07-02

申请号：US17309216

申请日：2019-11-11

Applicant: Solventum Intellectual Properties Company

Inventor： George W. Griesgraber ,  Bryon A. Merrill ,  Michael J. Rice

IPC: C07D471/04 ,  A61K31/4745 ,  A61P37/04

CPC classification number: C07D471/04 ,  A61K31/4745 ,  A61P37/04

Abstract: Imidazo[4,5-c]quinoline compounds having a substituent that is attached at the N−1 position by a branched group, single enantiomers of the compounds, pharmaceutical compositions containing the compounds, and methods of making the compounds are disclosed. Methods of use of the compounds as immune response modifiers, for inducing cytokine biosynthesis in humans and animals, and in the treatment of diseases including infectious and neoplastic diseases are also disclosed.