公开(公告)号：US06316002B1

公开(公告)日：2001-11-13

申请号：US09524508

申请日：2000-03-13

Applicant: Xin Liu ,  Chee-Keung Chung

Inventor： Xin Liu ,  Chee-Keung Chung

IPC: A61K3500

CPC classification number: A61K36/074 ,  C12N1/14

Abstract: The present invention describes a method for germination activating spores of red Ganoderma lucidum to produce bioactive substances which has medicinal effects on patients with immunological disorders, cancer, AIDS, hepatitis, diabetes, and cardiovascular diseases, and can prevent or inhibit free radical oxidation and hepatotoxic effects. The method can be subdivided into three stages. At the first stage, a germination activation method is introduced which includes soaking the spores in a solution to induce germination, and placing the germination treated spores in a culture box to induce the synthesis of bioactive substances and softening of the cell walls of the spores. At the second stage, sporoderm-broken ganoderma spores are collected by treating the epispores with cell wall breaking enzymes and/or mechanical force. At the last stage, the bioactive substances are extracted from the sporoderm-broken spores by drying at low temperature followed by extraction.

Abstract translation: 本发明描述了一种激活红色灵芝孢子的方法，以产生对免疫学疾病，癌症，艾滋病，肝炎，糖尿病和心血管疾病患者具有药效的生物活性物质，并且可以预防或抑制自由基氧化和肝毒性 效果。 该方法可以分为三个阶段。 在第一阶段，引入了一种发芽活化方法，其包括将孢子浸泡在溶液中以诱导发芽，并将发芽处理的孢子置于培养箱中以诱导生物活性物质的合成和孢子细胞壁的软化。 在第二阶段，通过用细胞壁断裂酶和/或机械力处理上皮细胞来收集孢子破碎的灵芝孢子。 在最后阶段，通过在低温下干燥，随后提取，从孢子孢破碎的孢子中提取生物活性物质。

公开(公告)号：US09619554B2

公开(公告)日：2017-04-11

申请号：US13288593

申请日：2011-11-03

Applicant: Xin Liu ,  Nitin Agrawal ,  James Francis Gilsinan, IV ,  James B. Lawson ,  Brian Whalen MacDonald ,  Mairéad Áine O'Donovan ,  Kimberly M. Vlcek ,  Nipoon Malhotra

Inventor： Xin Liu ,  Nitin Agrawal ,  James Francis Gilsinan, IV ,  James B. Lawson ,  Brian Whalen MacDonald ,  Mairéad Áine O'Donovan ,  Kimberly M. Vlcek ,  Nipoon Malhotra

IPC: G06F17/00 ,  G06F17/30

CPC classification number: G06F17/3064

Abstract: Systems, methods, and computer-readable storage media for providing query-completion suggestions configured to be searched against vertical information domains in response to receiving a general web search query are provided. At least a portion of a general web search query is received. As the portion of the general web search query is received, query-completion suggestions are determined as is a likely primary intent associated with at least a portion of the determined query-completion suggestions. If the likely primary intent associated with a particular query-completion suggestion is for information associated with a particular vertical information domain other than the general web domain, the query-completion suggestion is provided such that selection thereof causes searching of the query-completion suggestion against the particular information domain for search results.

公开(公告)号：US09522935B2

公开(公告)日：2016-12-20

申请号：US14764177

申请日：2014-01-27

Applicant: Xin Liu ,  Weidong Xie

Inventor： Xin Liu ,  Weidong Xie

IPC: A61K31/336 ,  C07D303/06 ,  C07J71/00 ,  G01N33/50 ,  C07J9/00 ,  C07J51/00

CPC classification number: C07J71/001 ,  A61K31/336 ,  C07D303/06 ,  C07J9/00 ,  C07J9/005 ,  C07J51/00 ,  G01N33/5011

Abstract: Lanosterol derivatives useful as anti-cancer agent, which can inhibit the growth of lung cancer cells, liver cancer cells, mammary cancer cells, brain cancer cells and pancreatic cancer cells, possibly by acting on the RHO pathway. These lanosterol derivatives are represented by compound LD030:

公开(公告)号：US09315496B2

公开(公告)日：2016-04-19

申请号：US14009581

申请日：2012-04-06

Applicant: Guisen Zhang ,  Yin Chen ,  Xiangqing Xu ,  Bifeng Liu ,  Xin Liu ,  Song Zhao ,  Shicheng Liu ,  Minquan Yu ,  Heng Zhang ,  Xinghua Liu

Inventor： Guisen Zhang ,  Yin Chen ,  Xiangqing Xu ,  Bifeng Liu ,  Xin Liu ,  Song Zhao ,  Shicheng Liu ,  Minquan Yu ,  Heng Zhang ,  Xinghua Liu

IPC: A61K31/496 ,  A61K31/454 ,  C07D405/12 ,  C07D405/14 ,  C07D413/12 ,  C07D413/14 ,  C07D417/12 ,  C07D417/14

CPC classification number: C07D417/12 ,  A61K31/454 ,  A61K31/496 ,  C07D405/12 ,  C07D405/14 ,  C07D413/12 ,  C07D413/14 ,  C07D417/14

Abstract: The present invention relates to the field of pharmaceutical chemistry, and in particular, to a benzopyrone derivative and a use thereof. The benzopyrone derivative is compound having a structure of formula (I) or a pharmaceutically acceptable salt thereof. It has been found by experiments that, this type of compounds is useful in prevention or treatment of neuropsychical diseases.

Abstract translation: 本发明涉及药物化学领域，特别涉及苯并吡喃酮衍生物及其应用。 苯并吡喃酮衍生物是具有式（I）结构的化合物或其药学上可接受的盐。 通过实验发现，这种类型的化合物可用于预防或治疗神经精神疾病。

公开(公告)号：US08829941B2

公开(公告)日：2014-09-09

申请号：US13316488

申请日：2011-12-10

Applicant: Xin Liu ,  Arvind Bomdica ,  Yikai Liang

Inventor： Xin Liu ,  Arvind Bomdica ,  Yikai Liang

IPC: H03K5/22

CPC classification number: H03F3/3022 ,  H03F3/45183 ,  H03F2203/45644 ,  H03F2203/45674 ,  H03F2203/45676

Abstract: A method is provided for receiving a differential signal pair input at a first circuit stage and converting the differential signal pair input to a single-ended signal at a second circuit stage. The method also provides for receiving an output of the first circuit stage and an output of the second stage at a third circuit stage and transmitting an amplified signal output from the third circuit stage. The method allows for a 60 dB signal gain or more. A circuit is also provided that includes multiple circuit stages that can provide signal gain to an input differential signal pair. The circuit converts the differential pair into a single-ended signal and transmits the amplified signal as an output. The circuit provides the signal gain without using a current mirror. A computer readable storage device encoded with data for adapting a manufacturing facility to create an apparatus is also provided.

Abstract translation: 提供一种用于接收在第一电路级输入的差分信号对，并在第二电路级将差分信号对输入转换为单端信号的方法。 该方法还提供在第三电路级接收第一电路级的输出和第二级的输出，并且传输从第三电路级输出的放大信号。 该方法允许60dB的信号增益或更多。 还提供了一种电路，其包括可向输入差分信号对提供信号增益的多个电路级。 电路将差分对转换为单端信号，并将放大的信号作为输出发送。 该电路在不使用电流镜的情况下提供信号增益。 还提供了一种用于适配制造设备以创建设备的数据编码的计算机可读存储设备。

公开(公告)号：US08795414B2

公开(公告)日：2014-08-05

申请号：US12997945

申请日：2009-07-08

Applicant: Xin Liu

Inventor： Xin Liu

IPC: B01D53/02

CPC classification number: B01D53/10 ,  B01D2253/102 ,  B01D2253/112 ,  B01D2257/302 ,  B01D2257/602 ,  F23J15/003 ,  F23J2215/20 ,  F23J2215/60 ,  F23J2219/30

Abstract: A process and system for feeding solids and carrier gases through the wall of a duct or chamber through which a gas stream flows to the flowing gas stream from a feed source exterior of the duct or chamber.

Abstract translation: 一种用于将固体和载气输送通过管道或室的壁的方法和系统，通过该管道或室的气流从管道或室的外部的进料源流入流动的气流。

公开(公告)号：US20140201669A1

公开(公告)日：2014-07-17

申请号：US14235140

申请日：2012-07-27

Applicant: Xin Liu ,  Sandeep Delal ,  Jochen Kruecker

Inventor： Xin Liu ,  Sandeep Delal ,  Jochen Kruecker

IPC: A61B19/00

Abstract: An ablation planning system includes a user interface (104) configured to permit selection of inputs for planning an ablation procedure. The user interface is further configured to incorporate selection of ablation probes and one or more combinations of ablation powers, durations or parameters applicable to selected probes in the inputs to size the ablation volumes. The user interface includes a display for rendering internal images of a patient, the display permitting visualizations of the ablation volumes for different entry points on the internal images. An optimization engine (106) is coupled to the user interface to receive the inputs and is configured to output an optimized therapy plan which includes spatial ablation locations and temporal information for ablation so that collateral damage is reduced, coverage area is maximized and critical structures are avoided in a planned target volume.

Abstract translation: 消融计划系统包括被配置为允许选择用于规划消融过程的输入的用户界面（104）。 用户界面还被配置为包括消融探针的选择以及适用于输入中的选定探针的消融功率，持续时间或参数的一个或多个组合以使消融体积大小。 用户界面包括用于呈现患者的内部图像的显示器，该显示器允许对内部图像上的不同入口点的消融量的可视化。 优化引擎（106）耦合到用户接口以接收输入，并被配置为输出优化的治疗计划，其包括用于消融的空间消融位置和时间信息，从而减少旁路损伤，覆盖区域最大化并且关键结构 避免在计划的目标量。

公开(公告)号：US08725238B2

公开(公告)日：2014-05-13

申请号：US12878800

申请日：2010-09-09

Applicant: Xin Liu ,  Yuanjin Zheng ,  Myint Wai Phyu ,  Bin Zhao

Inventor： Xin Liu ,  Yuanjin Zheng ,  Myint Wai Phyu ,  Bin Zhao

IPC: A61B5/0432

CPC classification number: A61B5/0452 ,  A61B5/0472 ,  A61B5/7203 ,  A61B5/7232 ,  A61B5/726

Abstract: An electrocardiogram signal processing system is provided which includes: a wavelet transformation unit comprising a plurality of outputs, each output being connected to one of a plurality of scales, wherein the wavelet transformation unit is adapted to transform an input electrocardiogram signal into a set of wavelets, each wavelet being output to one of the scales; a plurality of signal processing blocks, each of the signal processing blocks coupled to a respective output of the wavelet transformation unit and configured to receive and process the wavelet from the respective output, wherein the signal processing blocks provide processing functions which differ from one another.

Abstract translation: 提供了一种心电图信号处理系统，其包括：小波变换单元，包括多个输出，每个输出连接到多个刻度中的一个，其中所述小波变换单元适于将输入的心电图信号变换成一组小波 每个小波输出到一个秤; 多个信号处理块，每个信号处理块耦合到小波变换单元的相应输出并且被配置为从相应的输出接收和处理小波，其中信号处理块提供彼此不同的处理功能。

公开(公告)号：US20140127149A1

公开(公告)日：2014-05-08

申请号：US14125190

申请日：2012-05-17

Applicant: Carole A. Lepilleur ,  Dennis Malaba ,  John J. Mullay ,  Denise W. Rafferty ,  Duane G. Krzysik ,  Xin Liu ,  Eric H. Anderson

Inventor： Carole A. Lepilleur ,  Dennis Malaba ,  John J. Mullay ,  Denise W. Rafferty ,  Duane G. Krzysik ,  Xin Liu ,  Eric H. Anderson

IPC: A61K8/73 ,  A61Q19/04 ,  A61Q17/04 ,  A61Q19/08 ,  A61Q7/00 ,  A61Q5/00 ,  A61Q15/00 ,  A61Q5/10 ,  A61Q19/02 ,  A61Q11/00 ,  A61Q5/06 ,  A61Q19/06

CPC classification number: A61K8/737 ,  A61K8/97 ,  A61Q5/006 ,  A61Q5/02 ,  A61Q5/06 ,  A61Q5/10 ,  A61Q5/12 ,  A61Q7/00 ,  A61Q11/00 ,  A61Q15/00 ,  A61Q17/04 ,  A61Q19/02 ,  A61Q19/04 ,  A61Q19/06 ,  A61Q19/08 ,  C08B37/0087 ,  C08L5/00 ,  C11D3/225

Abstract: This invention relates to a cationically and amphiphilically modified polygalactomannan having repeating units with an average D-mannosyl to D-galactosyl residue ratio of at least 5 to 1 and to compositions containing same. A portion of the hydrogen atoms of hydroxyl groups situated on the mannosyl and galactosyl residues of the galactomannan are replaced with an amphiphilic and a cationic substituent.

Abstract translation: 本发明涉及具有平均D-甘露糖基至D-半乳糖基残基比例至少为5:1的重复单元的阳离子和两亲改性的聚半乳甘露聚糖以及含有它们的组合物。 位于半乳甘露聚糖的甘露糖基和半乳糖基残基的羟基的一部分氢原子被两亲性和阳离子取代基取代。

公开(公告)号：US20130297752A1

公开(公告)日：2013-11-07

申请号：US13462554

申请日：2012-05-02

Applicant: Shiva Bhanujan ,  Ethan M. Spiegel ,  Xin Liu

Inventor： Shiva Bhanujan ,  Ethan M. Spiegel ,  Xin Liu

IPC: G06F15/177

CPC classification number: H04L41/0803 ,  H04L41/046

Abstract: In one embodiment, a request is generated for a particular device of a computer network for a unique segment identifier (ID) for a network segment comprising one or more devices sharing a unique tenant ID. The request has a request-context that includes the tenant ID and a protocol of the network segment. The request is transmitted a segment ID manager and, as a result, the segment ID manager generates and transmits a response that indicates the unique segment ID for the network segment based on the request-context. Subsequently, the particular device may then be configured to communicate on the network segment with the one or more devices based on the unique segment ID of the response.

Abstract translation: 在一个实施例中，针对包括共享独特租户ID的一个或多个设备的网段的唯一段标识符（ID），为计算机网络的特定设备生成请求。 请求具有包括租户ID和网段的协议的请求上下文。 该请求被传送一个段ID管理器，结果，段ID管理器基于请求上下文生成并发送指示网段的唯一段ID的响应。 随后，特定设备然后可以被配置为基于响应的唯一段ID在网段上与一个或多个设备进行通信。