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81.发明授权Pharmaceutical compositions containing compounds with a flavanone skeleton, process for the preparation of the said compound and novel compounds obtained 失效含有具有黄酮酮骨架的化合物的药物组合物，所述化合物的制备方法和获得的新化合物
公开(公告)号：US4636569A
公开(公告)日：1987-01-13
申请号：US587684
申请日：1984-03-06
IPC分类号： A61K31/35 , A61K31/352 , A61P1/16 , A61P3/06 , A61P11/10 , C07D311/32 , C07D311/04
CPC分类号： C07D311/32
摘要： Compounds with a flavanone skeleton having the formula I ##STR1## in which R.sub.1 and R.sub.2, which may be the same or different, represent hydrogen, hydroxyl, methoxyl, thiomethyl, amino or substituted amino, are endowed with expectorant, mucolytic, mucopoietic, choleretic and hypolipaemia-producing activity.
摘要翻译： 具有式I的黄酮酮骨架的化合物（I）其中可以相同或不同的R 1和R 2表示氢，羟基，甲氧基，硫代甲基，氨基或取代的氨基，赋予祛痰剂，粘液溶解， 造血，胆汁淤血和降血脂产生活性。
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公开(公告)号：US4157894A
公开(公告)日：1979-06-12
申请号：US801398
申请日：1977-05-27
申请人： Ezio Bombardelli
发明人： Ezio Bombardelli
IPC分类号： A61K36/25 , A61K20060101 , A61K36/258 , C07G20060101 , C07J17/00 , C07J71/00 , G01N30/06 , G01N33/00 , G01N33/15 , G01N31/08
CPC分类号： A61K36/258 , Y10T436/143333 , Y10T436/200833 , Y10T436/255
摘要： A method for producing a purified extract of ginseng root which comprises contacting an aqueous extract of ginseng root with a solid absorption resin so as to absorb active saponins contained in the extract on the resin and eluting active saponins from the resin.Also a method of analyzing a ginseng extract which comprises subjecting the extract to silylation to convert saponins contained in the extract to trimethylsilyl ethers, separating the ethers by gas-liquid chromatography and detecting the separated ethers.
摘要翻译： 一种人参根的纯化提取物的制造方法，其特征在于，使人参根的水提物与固体吸收树脂接触，吸收树脂提取物中含有的活性皂苷并从树脂中洗脱活性皂苷。
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83.发明授权Compositions comprising Andrographis paniculata extracts combined with Ginkgo biloba extracts complexed with phospholipids, and their use 有权包含与穿心莲提取物组合的银杏叶提取物与磷脂复合的组合物及其用途公开(公告)号：US09192636B2
公开(公告)日：2015-11-24
申请号：US13520154
申请日：2011-01-03
申请人： Ezio Bombardelli , Andrea Giori
发明人： Ezio Bombardelli , Andrea Giori
IPC分类号： A61K36/16 , A61K36/19 , A61K36/185
CPC分类号： A61K36/16 , A61K36/19 , A61K2300/00
摘要： The present invention relates to compositions comprising Andrographis paniculata extracts combined with Ginkgo biloba extracts complexed with phospholipids.Moreover, the compositions administered in oils rich in ω-3 polyunsaturated fatty acids demonstrate a further synergic effect between the ingredients.Said compositions are useful in the treatment of neurodegenerative disorders, in particular Alzheimer's disease and multiple sclerosis.
摘要翻译： 本发明涉及包含与磷脂相结合的银杏提取物组合的穿心莲提取物的组合物。 此外，在富含ω-3多不饱和脂肪酸的油中施用的组合物在成分之间表现出进一步的协同作用。 所述组合物可用于治疗神经变性疾病，特别是阿尔茨海默氏病和多发性硬化症。
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84.发明授权Formulations for the treatment of mucositis induced by antitumor or immunosuppressive therapy 有权用于治疗由抗肿瘤或免疫抑制治疗诱导的粘膜炎的制剂公开(公告)号：US08940338B2
公开(公告)日：2015-01-27
申请号：US12812065
申请日：2009-01-08
申请人： Ezio Bombardelli , Gabriele Fontana
发明人： Ezio Bombardelli , Gabriele Fontana
IPC分类号： A61K31/4355 , A61K9/68 , C07D491/22 , A61P1/04 , A61P29/00 , A61P15/02 , B60S3/06
CPC分类号： B60S3/063
摘要： Formulations containing sanguinarine or chelerythrine or the salts thereof or extracts containing them in admixture with suitable carriers and/or excipients for the treatment and/or prevention of mucositis.
摘要翻译： 含有血根碱或白藜芦醇或其盐的制剂或含有它们的提取物与适合的载体和/或赋形剂的混合物用于治疗和/或预防粘膜炎。
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公开(公告)号：US20120270825A1
公开(公告)日：2012-10-25
申请号：US13539970
申请日：2012-07-02
IPC分类号： A61K31/7028 , A61P29/00 , A61P19/02
CPC分类号： A61K36/76 , A61K9/4858
摘要： The present invention relates to an extract of Salix spp obtainable by fractioning on a resin and to the process for its preparation.The extract of the invention is characterized by an high content in salicin derivatives, reduced content in high molecular tannins and a content in proanthocyanidins sufficient to inhibit some tissue metal proteases. The product is formulated in oils rich in ω-3 and ω-6 acids which provide a better absorption of the extract active principles, also increasing synergetically their action.
摘要翻译： 本发明涉及通过在树脂上分级得到的柳叶螨提取物及其制备方法。 本发明的提取物的特征在于水杨苷衍生物含量高，高分子单宁含量降低，原花色素含量足以抑制一些组织金属蛋白酶。 该产品被配制成富含ω-3和ω-6酸的油，其提供了对提取物活性成分的更好吸收，同时也增加了它们的作用。
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86.发明授权公开(公告)号：US07993683B2
公开(公告)日：2011-08-09
申请号：US12376452
申请日：2007-07-27
申请人： Ezio Bombardelli , Paolo Morazzoni
发明人： Ezio Bombardelli , Paolo Morazzoni
IPC分类号： A61K36/00 , A61K31/7012
CPC分类号： A61K31/7012 , A61K31/70 , A61K31/7008 , A61K36/185 , A61K36/19 , A61K36/76 , A61K2300/00
摘要： Compositions comprising: saligenin or derivatives thereof or Salix ssp extracts containing from 10 to 50% of saligenin; substantially pure andrographolide or andrographolide enriched Andrographis paniculata extract containing from 5 to 30% of andrographolide; optionally N-acetyl-glucosamine and/or glucuronic acid or glucuronolactone.
摘要翻译： 组合物，其包含：水杨苷或其衍生物或含有10至50％的水杨苷的Salix ssp提取物; 穿透穿心莲内酯或富含穿心莲内酯的穿心莲提取物含有5至30％的穿心莲内酯; 任选的N-乙酰基 - 葡糖胺和/或葡糖醛酸或葡糖醛酸内酯。
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87.发明申请FORMULATIONS WITH SANGUINARINE, CHELERYTHRINE OR CHELIDONINE FOR THE TREATMENT OF WARTS, VERRUCAS AND PSORIATIC PLAQUES 有权用于治疗战争，威胁和精神病毒药物的配方与香兰素，儿茶素或儿茶素公开(公告)号：US20110014306A1
公开(公告)日：2011-01-20
申请号：US12921476
申请日：2009-03-09
IPC分类号： A61K36/28 , A61K36/66 , A61K36/87 , A61K31/4355 , A61P17/06 , A61K36/758 , A61P17/12
CPC分类号： A61K36/66 , A61K31/4741 , A61K36/75 , Y10S514/863
摘要： The invention provides formulations containing sanguinarine, chelerythrine or chelidonine or their salts or extracts containing them, mixed with suitable vehicles and/or excipients, for the treatment of common skin warts and verrucas, anal and vulvar warts and psoriatic plaques.
摘要翻译： 本发明提供含有血根碱，螯合物或螯合物或其含有它们的盐或提取物的配方，与合适的载体和/或赋形剂混合，用于治疗常见的皮肤疣和疣状，肛门和外阴疣以及牛皮癣斑块。
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公开(公告)号：US20100120816A1
公开(公告)日：2010-05-13
申请号：US12374963
申请日：2007-07-13
IPC分类号： A61K31/4375 , C07D491/147 , A61P35/00
CPC分类号： C07D491/22
摘要： Novel camptothecin derivatives having antitumor activity, the processes for the preparation thereof, the use thereof as antitumor drugs and pharmaceutical compositions containing them.
摘要翻译： 具有抗肿瘤活性的新型喜树碱衍生物，其制备方法，其作为抗肿瘤药物的用途和含有它们的药物组合物。
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公开(公告)号：US07691422B2
公开(公告)日：2010-04-06
申请号：US10570943
申请日：2004-09-10
申请人： Ezio Bombardelli
发明人： Ezio Bombardelli
CPC分类号： A61K36/16 , A61K36/23 , A61K36/87 , A61K2300/00
摘要： The present invention relates to oral pharmaceutical and cosmetic compositions for the treatment of cellulite containing Vitis vinifera extracts, Centella asiatica triterpenes and dimeric Ginkgo biloba flavonoids, in the free form or complexed with phospholipids.
摘要翻译： 本发明涉及用于治疗含有葡萄酒提取物，积雪草三叶萜和二聚银杏叶黄酮的脂肪团的口服药物和化妆品组合物，其为游离形式或与磷脂络合。
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公开(公告)号：US20100063082A1
公开(公告)日：2010-03-11
申请号：US12374799
申请日：2007-07-12
IPC分类号： A61K31/4375 , C07D471/22 , A61P35/00
CPC分类号： Y02P20/55
摘要： Novel camptothecin derivatives having antitumor activity, the processes for the preparation thereof, the use thereof as antitumor drugs and pharmaceutical compositions containing them.
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