公开(公告)号：US08696679B2

公开(公告)日：2014-04-15

申请号：US11953800

申请日：2007-12-10

申请人： John H. Shadduck ,  Csaba Truckai

发明人： John H. Shadduck ,  Csaba Truckai

IPC分类号： A61F2/00

CPC分类号： A61B17/8836 ,  A61B17/7095 ,  A61B17/8822 ,  A61B2017/00039 ,  A61B2017/00544

摘要： The present invention relates in certain embodiments to methods, systems, and devices for treating vertebral compression fractures. In one embodiment, a bone cement injector is advanced into bone and injects a bone cement flow through the injector and a vapor flow from at least one vapor outlet in the injector. In another embodiment, the bone treatment system comprises an elongated member having a flow passageway, a bone fill material source, and a vapor source coupleable to the flow passageway. Still another embodiment describes a vapor injection device having an elongated member with a flow passageway, the elongated member configured for insertion into a bone and for delivering a bone fill material through the flow passageway, and having at least one vapor channel in communication with the flow passageway to deliver a vapor into the flow passageway to heat a bone fill material flow.

摘要翻译： 本发明在某些实施例中涉及用于治疗椎骨压缩性骨折的方法，系统和装置。 在一个实施例中，骨粘固剂注射器被推进到骨中并且注入穿过注射器的骨水泥流和来自注射器中的至少一个蒸气出口的蒸汽流。 在另一个实施例中，骨治疗系统包括具有流动通道，骨填充材料源和可耦合到流动通道的蒸气源的细长构件。 另一个实施例描述了具有带有流动通道的细长构件的蒸气喷射装置，细长构件构造成用于插入骨骼中并且用于通过流动通道输送骨填充材料，并且具有与流体连通的至少一个蒸汽通道 通道以将蒸气输送到流动通道中以加热骨填充物料流。

公开(公告)号：US08523871B2

公开(公告)日：2013-09-03

申请号：US12062337

申请日：2008-04-03

申请人： Csaba Truckai ,  Robert Luzzi ,  John H. Shadduck ,  Robert D. Poser

发明人： Csaba Truckai ,  Robert Luzzi ,  John H. Shadduck ,  Robert D. Poser

IPC分类号： A61B17/58 ,  A61B17/60 ,  A61F2/00

CPC分类号： A61B17/8836 ,  A61B17/8822 ,  A61B2017/00022

摘要： Systems and methods for delivering bone cement into a bone can include a handle body defining a flow path, a thermal emitter in the handle body to apply energy to bone cement passing through the flow path, a source of bone cement and an injection cannula. The cannula can be in communication with the flow path such that inserting the cannula into a bone can allow a flow of bone cement therethrough to an opening at a distal end of the cannula. Other systems and methods for delivering bone cement into a bone can include an injector body with a handle portion, and a cannula, a bone cement container, a low pressure drive mechanism configured to effect a flow of bone cement from said container to the injector body and a high pressure drive mechanism configured to effect a flow of bone cement through the injector body into the bone.

公开(公告)号：US20130172805A1

公开(公告)日：2013-07-04

申请号：US13534908

申请日：2012-06-27

申请人： Csaba Truckai ,  Aaron Germain ,  Kyle Klein ,  John H. Shadduck ,  Michael D. Walker ,  Benedeck Orczy-Timko ,  Balazs Lesko

发明人： Csaba Truckai ,  Aaron Germain ,  Kyle Klein ,  John H. Shadduck ,  Michael D. Walker ,  Benedeck Orczy-Timko ,  Balazs Lesko

IPC分类号： A61M1/00

CPC分类号： A61B17/42 ,  A61B17/3205 ,  A61B18/1485 ,  A61B2017/4216 ,  A61B2018/00196 ,  A61B2018/00559 ,  A61B2018/00601 ,  A61M1/0031 ,  A61M1/0058 ,  A61M1/006 ,  A61M1/008 ,  A61M3/0229

摘要： A fluid management system for use with a fluid reservoir includes an inflow pump and an outflow pump. The inflow pump is connectable to a probe for delivering a distention fluid to a body cavity. The outflow pump removes the distention fluid through the same probe, thus establishing a re-circulating volume of distention fluid within the body cavity. The removed fluid is filtered and returned to a fluid reservoir for eventual recycling to the body cavity. A controller adjusts the flow rates of the inflow pump and the outflow pump to maintain a pre-selected fluid pressure or volume within the body cavity.

摘要翻译： 用于流体储存器的流体管理系统包括流入泵和流出泵。 流入泵可连接到用于将膨胀流体输送到体腔的探针。 流出泵通过相同的探针去除膨胀流体，从而在体腔内建立膨胀流体的再循环体积。 去除的流体被过滤并返回到流体储存器，以最终循环到体腔。 控制器调节流入泵和流出泵的流量，以维持体腔内的预先选定的流体压力或体积。

公开(公告)号：US20130046304A1

公开(公告)日：2013-02-21

申请号：US13531309

申请日：2012-06-22

申请人： Aaron Germain ,  Kyle Klein ,  Benedek Orczy-Timko ,  Michael D. Walker ,  John H. Shadduck ,  Csaba Truckai ,  Balazs Lesko

发明人： Aaron Germain ,  Kyle Klein ,  Benedek Orczy-Timko ,  Michael D. Walker ,  John H. Shadduck ,  Csaba Truckai ,  Balazs Lesko

IPC分类号： A61B17/42 ,  A61B18/18

CPC分类号： A61B18/1485 ,  A61B17/32002 ,  A61B18/1482 ,  A61B18/18 ,  A61B2017/320028 ,  A61B2018/00083 ,  A61B2018/00196 ,  A61B2018/00559 ,  A61B2018/00601 ,  A61B2018/00982 ,  A61B2018/142 ,  A61B2218/002 ,  A61B2218/007

摘要： The tissue cutting device comprises an elongated assembly including both an outer sleeve and an inner sleeve. The outer sleeve has a tissue-receiving window, and the inner sleeve has a distal end which cuts tissue as the inner sleeve is advanced past the window. The tissue is received into a lumen of the inner sleeve, and the inner sleeve lumen is typically enlarged in a proximal direction to reduce the tendency of resected tissue to lodge therein. The tissue displacement member is optionally provided at a distal end of the outer sleeve to further aid in dislodging tissue which becomes captured in a distal end of the inner sleeve of the lumen.

公开(公告)号：US08348955B2

公开(公告)日：2013-01-08

申请号：US12786362

申请日：2010-05-24

申请人： Csaba Truckai ,  John H. Shadduck

发明人： Csaba Truckai ,  John H. Shadduck

IPC分类号： A61F2/44

CPC分类号： A61B17/8805 ,  A61B17/70 ,  A61B17/8822 ,  A61B17/8827 ,  A61B17/8836 ,  A61B2017/00022 ,  A61B2017/00026 ,  A61B2017/00084 ,  A61B2017/564 ,  A61F2/44

摘要： The present invention relates in certain embodiments to medical devices for treating vertebral compression fractures. More particularly, embodiments of the invention relate to instruments and methods for controllably restoring vertebral body height by controlling the flow of bone cement into the interior of a vertebra and the application of forces causes by the cement flow. An exemplary system utilizes Rf energy in combination a conductive bone cement for selectively polymerizing the inflow plume to increase the viscosity of the cement. In one aspect of the invention, the system utilizes a controller to control bone cement flow parameters to either, allow or disallow cement interdigitation into cancellous bone. A method of the invention includes pulsing the flows of bone cement wherein high acceleration of the flow pulses can apply expansion forces across the surface of the cement plume to reduce a vertebral fracture.

摘要翻译： 本发明在某些实施例中涉及用于治疗脊椎压缩性骨折的医疗装置。 更具体地，本发明的实施例涉及通过控制骨水泥进入椎骨内部并且由水泥流引起的力的施加来可控地恢复椎体高度的仪器和方法。 一个示例性系统利用Rf能量组合导电骨水泥，用于选择性聚合流入羽流以增加水泥的粘度。 在本发明的一个方面，该系统利用控制器来控制骨水泥流动参数，以允许或不允许水泥交叉指向松质骨。 本发明的方法包括脉动骨粘固剂的流动，其中流动脉冲的高加速度可以施加穿过水泥羽流表面的膨胀力，以减少椎骨骨折。

公开(公告)号：US08048083B2

公开(公告)日：2011-11-01

申请号：US11267950

申请日：2005-11-04

申请人： John H. Shadduck ,  Csaba Truckai

发明人： John H. Shadduck ,  Csaba Truckai

IPC分类号： A61B17/56 ,  A61F2/44

CPC分类号： A61B17/7098

摘要： Methods and instruments for treating an osteoporotic vertebral body or for treating a vertebral compression fracture. An exemplary method includes introducing an open knit structure together with a bone cement into a bone wherein the knit structure extends substantially throughout the interior of the cement volume. In one aspect of the invention, the bone cement volumes cures with the filament structure reinforcing the cement. In another aspect of the invention, the open knit structure is configured to direct flows of bone cement to apply forces for reducing a vertebral compression fracture. In another aspect of the invention, the system provides bone cement flows that extend through the knit structure thus allowing the cement to fully interdigitate with the cancellous bone.

摘要翻译： 用于治疗骨质疏松性椎体或用于治疗椎体压缩性骨折的方法和手段。 一种示例性的方法包括将开放的针织结构与骨水泥一起引入到骨中，其中针织结构基本上在水泥体积的整个内部延伸。 在本发明的一个方面，骨水泥体积固化，细丝结构增强了水泥。 在本发明的另一方面，开放针织结构被配置为引导骨粘固剂的流动以施加用于减少椎骨压缩性骨折的力。 在本发明的另一方面，该系统提供延伸穿过针织结构的骨水泥流，从而允许水泥与松质骨完全交叉指向。

公开(公告)号：US07981113B2

公开(公告)日：2011-07-19

申请号：US12098560

申请日：2008-04-07

申请人： Csaba Truckai ,  John H. Shadduck ,  Bruno Strul

发明人： Csaba Truckai ,  John H. Shadduck ,  Bruno Strul

IPC分类号： A61B18/12

CPC分类号： A61B18/1445 ,  A61B18/1442 ,  A61B2018/00077 ,  A61B2018/00083 ,  A61B2018/00125 ,  A61B2018/00148 ,  A61B2018/0016 ,  A61B2018/00404 ,  A61B2018/00601 ,  A61B2018/0063 ,  A61B2018/1412 ,  A61B2018/1455

摘要： An embodiment of the invention includes an electrosurgical jaw structure that carries cooperating PTC bodies in both series and parallel circuit components for controlled RF energy application to engaged tissue to effectively weld tissue.

摘要翻译： 本发明的实施例包括电外科钳口结构，其在串联和并联电路部件中携带协作的PTC体，用于受控RF能量施加到接合组织以有效地焊接组织。

公开(公告)号：US07955331B2

公开(公告)日：2011-06-07

申请号：US11080101

申请日：2005-03-14

申请人： Csaba Truckai ,  John H. Shadduck

发明人： Csaba Truckai ,  John H. Shadduck

IPC分类号： A61B18/14

CPC分类号： A61B18/1442

摘要： A particular embodiment of the invention provides an electrosurgical working end for performing high strength welding of tissue comprising a body having a tissue contacting energy delivery surface. The body includes pixel portions and non-pixel portions distributed within the tissue contacting surface. The pixel portions comprise a positive temperature coefficient of resistance (PTCR) material with at least one pixel portion configured to switch Rf current on and off in the at least one pixel portion responsive to tissue temperature adjacent the at least one pixel portion. The pixel portions can be configured to be coupled to an Rf current source such as an Rf generator. The pixelated energy delivery surfaces are capable of highly localized modulation of Rf energy application to the engaged tissue to create high strength tissue welds.

摘要翻译： 本发明的一个具体实施方案提供了一种电外科工作端，用于对组织进行高强度焊接，包括具有组织接触能量输送表面的主体。 主体包括分布在组织接触表面内的像素部分和非像素部分。 像素部分包括正温度系数电阻（PTCR）材料，其中至少一个像素部分被配置成响应于与至少一个像素部分相邻的组织温度在至少一个像素部分中开启和关闭Rf电流。 像素部分可以被配置为耦合到诸如Rf发生器的Rf电流源。 像素化的能量传递表面能够对接合的组织进行Rf能量的高度局部调节，以产生高强度组织焊接。

公开(公告)号：US20100280520A1

公开(公告)日：2010-11-04

申请号：US12786362

申请日：2010-05-24

申请人： Csaba Truckai ,  John H. Shadduck

发明人： Csaba Truckai ,  John H. Shadduck

IPC分类号： A61B17/56

CPC分类号： A61B17/8805 ,  A61B17/70 ,  A61B17/8822 ,  A61B17/8827 ,  A61B17/8836 ,  A61B2017/00022 ,  A61B2017/00026 ,  A61B2017/00084 ,  A61B2017/564 ,  A61F2/44

摘要： The present invention relates in certain embodiments to medical devices for treating vertebral compression fractures. More particularly, embodiments of the invention relate to instruments and methods for controllably restoring vertebral body height by controlling the flow of bone cement into the interior of a vertebra and the application of forces causes by the cement flow. An exemplary system utilizes Rf energy in combination a conductive bone cement for selectively polymerizing the inflow plume to increase the viscosity of the cement. In one aspect of the invention, the system utilizes a controller to control bone cement flow parameters to either, allow or disallow cement interdigitation into cancellous bone. A method of the invention includes pulsing the flows of bone cement wherein high acceleration of the flow pulses can apply expansion forces across the surface of the cement plume to reduce a vertebral fracture.

摘要翻译： 本发明在某些实施例中涉及用于治疗脊椎压缩性骨折的医疗装置。 更具体地，本发明的实施例涉及通过控制骨水泥进入椎骨内部并且由水泥流引起的力的施加来可控地恢复椎体高度的仪器和方法。 一个示例性系统利用Rf能量组合导电骨水泥，用于选择性聚合流入羽流以增加水泥的粘度。 在本发明的一个方面，该系统利用控制器来控制骨水泥流动参数，以允许或不允许水泥交叉指向松质骨。 本发明的方法包括脉动骨粘固剂的流动，其中流动脉冲的高加速度可以施加穿过水泥羽流表面的膨胀力，以减少椎骨骨折。

公开(公告)号：US07722620B2

公开(公告)日：2010-05-25

申请号：US11209035

申请日：2005-08-22

申请人： Csaba Truckai ,  John H. Shadduck

发明人： Csaba Truckai ,  John H. Shadduck

IPC分类号： A61B17/00

CPC分类号： A61B17/8805 ,  A61B17/70 ,  A61B17/8822 ,  A61B17/8827 ,  A61B17/8836 ,  A61B2017/00022 ,  A61B2017/00026 ,  A61B2017/00084 ,  A61B2017/564 ,  A61F2/44

摘要： The present invention relates in certain embodiments to medical devices for treating vertebral compression fractures. More particularly, embodiments of the invention relate to instruments and methods for controllably restoring vertebral body height by controlling the flow of bone cement into the interior of a vertebra and the application of forces causes by the cement flow. An exemplary system utilizes Rf energy in combination a conductive bone cement for selectively polymerizing the inflow plume to increase the viscosity of the cement. In one aspect of the invention, the system utilizes a controller to control bone cement flow parameters to either allow or disallow cement interdigitation into cancellous bone. A method of the invention includes pulsing the flows of bone cement wherein high acceleration of the flow pulses can apply expansion forces across the surface of the cement plume to reduce a vertebral fracture.

摘要翻译： 本发明在某些实施例中涉及用于治疗脊椎压缩性骨折的医疗装置。 更具体地，本发明的实施例涉及通过控制骨水泥进入椎骨内部并且由水泥流引起的力的施加来可控地恢复椎体高度的仪器和方法。 示例性系统利用结合导电骨水泥的Rf能量来选择性聚合流入羽流以增加水泥的粘度。 在本发明的一个方面，该系统利用控制器来控制骨水泥流动参数以允许或不允许水泥交叉指向松质骨。 本发明的方法包括脉动骨粘固剂的流动，其中流动脉冲的高加速度可以施加穿过水泥羽流表面的膨胀力，以减少椎骨骨折。