公开(公告)号：USD363429S

公开(公告)日：1995-10-24

申请号：US19420

申请日：1994-03-01

申请人： William Lee

设计人： William Lee

公开(公告)号：US20190026641A1

公开(公告)日：2019-01-24

申请号：US15872731

申请日：2018-01-16

申请人： James Lu ,  Jim Chou ,  William Lee ,  Chris Williams ,  James Warren ,  Ruomu Jiang

发明人： James Lu ,  Jim Chou ,  William Lee ,  Chris Williams ,  James Warren ,  Ruomu Jiang

IPC分类号： G06N7/00 ,  G06F19/22 ,  G06F17/18 ,  G06N99/00

摘要： Systems, platforms, methods and media for providing genomic services are disclosed. In one example, a genomic services platform comprises a network interface through which are received genomic sequence reads derived from a biological sample obtained from a user. The platform also includes a bioinformatics processing pipeline including a read alignment module configured to generate observed sequence data by aligning the sequence reads relative to a reference sequence, a variant calling module operative to identify observed variants in the observed sequence data, and a variant refinement module for producing genotype data including a set of refined variants associated with the user. A variant imputation module produces a set of imputed variants associated with the user, and is configured to receive, as input, at least some of the genotype data and separate the genotype data into high-quality and low-quality genotypes based on a genotype quality.

公开(公告)号：US20190026156A1

公开(公告)日：2019-01-24

申请号：US15872793

申请日：2018-01-16

申请人： James Lu ,  Jim Chou ,  William Lee ,  Chris Williams ,  James Warren ,  Ruomu Jiang

发明人： James Lu ,  Jim Chou ,  William Lee ,  Chris Williams ,  James Warren ,  Ruomu Jiang

IPC分类号： G06F9/50 ,  G06F19/28 ,  G06F19/18 ,  G06F8/30 ,  G06F8/34 ,  G06F9/48

摘要： Systems, platforms, methods and media for providing genomic services are disclosed. In one example, a genomic services platform comprises a network interface through which genomic sequence reads derived from a biological sample are received. The platform also includes a bioinformatics processing pipeline that comprises a read alignment module configured to generate observed sequence data by aligning the sequence reads relative to a reference sequence, a variant calling module operative to identify observed variants in the observed sequence data, and a variant refinement module for producing a set of refined variants associated with the biological sample. A variant imputation module produces a set of imputed variants associated with the user and a variant storage module, operating on a server-less framework, is disposed to receive a query from network infrastructure of a partner application provider and to provide selected ones of the refined or imputed variants m response to the query.

公开(公告)号：US09618131B2

公开(公告)日：2017-04-11

申请号：US14794526

申请日：2015-07-08

申请人： William Lee

发明人： William Lee

IPC分类号： F16K7/17 ,  F16K15/14

CPC分类号： F16K15/148 ,  B65D77/225 ,  F16K7/17

摘要： A one way valve is revealed. The one way valve includes a valve seat and a valve member supported by the valve seat. A hole is mounted at a center of the valve base while an outer circular base is disposed around the hole and an inner circular base is arranged at a center of the hole. The inner circular base has a circular sidewall around an opening. At least one gap is radially formed on the circular sidewall and the gap is vertically penetrating the circular sidewall. The valve member consists of a membrane portion and a rod portion extended from one side of the membrane portion. Thereby the rod portion is passed through the gap of the inner circular base to be set into the opening of the inner circular base.

公开(公告)号：US08210501B2

公开(公告)日：2012-07-03

申请号：US12483772

申请日：2009-06-12

申请人： William Lee

发明人： William Lee

IPC分类号： F16K31/00

CPC分类号： F16K15/20 ,  B63C9/24 ,  F16K15/063 ,  F16K15/18 ,  Y10T137/0491 ,  Y10T137/3724

摘要： An inflation valve is revealed. The inflation valve includes a longitudinal valve body, a valve member and an elastic member sleeved between the valve member and the longitudinal valve body. The longitudinal valve body includes an axially extending hole disposed therein, a projecting edge arranged on the axially extending hole and a round through hole disposed on a center of the projecting edge, and two alignment members having at least one projecting body and/or one concave slot. A round valve head is arranged on the front end of the valve member and alignment members corresponding to the alignment members of the longitudinal valve body disposed on an outer edge of the valve head. While being assembled, the valve head passes the through hole by alignment of the alignment members between the valve member and the longitudinal valve body and becomes staggered. Moreover, by the elastic member, the valve head presses and locks onto the round through hole to form a closed state.

摘要翻译： 透露充气阀。 充气阀包括纵向阀体，阀构件和套在阀构件和纵向阀体之间的弹性构件。 所述纵阀体包括设置在其中的轴向延伸的孔，设置在所述轴向延伸孔上的突出边缘和设置在所述突出边缘的中心的圆形通孔，以及两个对准构件，其具有至少一个突出体和/ 槽 在阀构件的前端设置有圆形阀头，对置构件，其对应于设置在阀头的外缘上的纵向阀体的对准构件。 在组装时，阀头通过对准阀构件和纵向阀体之间的对准构件而通过通孔，并且变得交错。 此外，通过弹性构件，阀头按压并锁定在圆形通孔上以形成关闭状态。

公开(公告)号：US08001283B2

公开(公告)日：2011-08-16

申请号：US12047257

申请日：2008-03-12

申请人： William Lee ,  Thomas Benjamin Berg

发明人： William Lee ,  Thomas Benjamin Berg

IPC分类号： G06F12/00 ,  G06F13/00

CPC分类号： G06F9/5038 ,  G06F12/0815

摘要： A system, apparatus and method for managing input/output requests in a multi-processor system is disclosed. An IO coherence unit includes an IO request handler, a variable size transaction table, and an IO response handler. The size of the transaction table varies according to the number of pending IO requests. The IO request handler stores information about pending IO requests in the transaction table to establish an order among related requests and to permit out-of-order handling of unrelated requests. The IO response handler tracks responses to the IO requests and updates the information in the transaction table. The IO coherence unit returns responses to requesting devices in compliance with device ordering requirements.

摘要翻译： 公开了一种用于在多处理器系统中管理输入/输出请求的系统，装置和方法。 IO相干单元包括IO请求处理程序，可变大小事务表和IO响应处理程序。 交易表的大小根据挂起的IO请求数量而变化。 IO请求处理程序将关于待处理IO请求的信息存储在事务表中，以便在相关请求之间建立一个顺序，并允许无序处理不相关的请求。 IO响应处理程序跟踪对IO请求的响应，并更新事务表中的信息。 IO相干单元根据设备订购要求返回对请求设备的响应。

公开(公告)号：US07824485B2

公开(公告)日：2010-11-02

申请号：US12027079

申请日：2008-02-06

申请人： Paul J. Buras ,  William Lee ,  James R. Butler

发明人： Paul J. Buras ,  William Lee ,  James R. Butler

IPC分类号： C08L95/00 ,  C09D195/00

CPC分类号： C09D195/00 ,  C08K3/20 ,  C08L95/00 ,  C08L2666/02

摘要： Asphalt compositions and methods of forming such are described herein. The asphalt compositions and methods of forming such are generally adapted to enable open air processing while producing asphalt compositions that exhibit properties capable of meeting SUPERPAVE™ specifications.

摘要翻译： 本文描述了沥青组合物及其形成方法。 沥青组合物及其形成方法通常适于在露出空气处理的同时生产具有能够满足SUPERPAVE TM规格的性能的沥青组合物。

公开(公告)号：US07645820B2

公开(公告)日：2010-01-12

申请号：US12108807

申请日：2008-04-24

申请人： Paul J. Buras ,  Joseph R. Bruns ,  William Lee

发明人： Paul J. Buras ,  Joseph R. Bruns ,  William Lee

IPC分类号： C08L95/00

CPC分类号： C08L95/00 ,  C08K3/22 ,  C08L9/06 ,  C08L2666/02 ,  C08L53/00 ,  C08L2666/08

摘要： In methods of preparing asphalt and elastomeric polymer compositions crosslinked with phenol aldehyde resins and sulfur, such as polymer modified asphalt (PMA), it has been discovered that the MP1 compatibility may be improved by adding certain ionic metal oxides. Suitable ionic metal salts include, but are not necessarily limited to, zinc oxide, cadmium oxide, and the like. Acceptable elastomeric polymers include, but are not necessarily limited to, styrene-butadiene copolymers. Additional sulfur-containing crosslinkers may also be used.

摘要翻译： 在制备用酚醛树脂和硫交联的沥青和弹性体聚合物组合物如聚合物改性沥青（PMA）的方法中，已经发现通过加入某些离子金属氧化物可以改善MP1的相容性。 合适的离子金属盐包括但不一定限于氧化锌，氧化镉等。 可接受的弹性体聚合物包括但不一定限于苯乙烯 - 丁二烯共聚物。 还可以使用另外的含硫交联剂。

公开(公告)号：US07608650B2

公开(公告)日：2009-10-27

申请号：US12367303

申请日：2009-02-06

申请人： Paul Buras ,  William Lee ,  James Butler ,  Wendy Stanley

发明人： Paul Buras ,  William Lee ,  James Butler ,  Wendy Stanley

IPC分类号： C08L95/00

CPC分类号： E01C7/18 ,  C08L9/06 ,  C08L81/04 ,  C08L95/00 ,  C08L2666/08

摘要： Asphalt and elastomeric polymer compositions crosslinked with mixed polythiomorpholines or at least one alkyl polysulfide can give polymer modified asphalts (PMAs) with improved properties and/or reduced H2S evolution. When at least one alkyl polysulfide is used to completely or partially replace conventional crosslinkers such as S or MBT, mercaptobenzimidazole (MBI) may be optionally used as a co-crosslinker. The use of mixed polythiomorpholines as crosslinkers provide PMAs with better low temperature profiles (BBR m-values). The use of at least one alkyl polysulfide crosslinker gives PMAs with improved PAV-aged DSR results, and reduced H2S evolution. The use of at least one alkyl polysulfide crosslinker together with MBI may give PMAs with improved PAV DSR Fail Temperatures.

摘要翻译： 用混合多硫代吗啉或至少一种烷基多硫化物交联的沥青和弹性聚合物组合物可以得到具有改进性能和/或降低的H 2 S进化的聚合物改性沥青（PMA）。 当使用至少一种烷基多硫化物来完全或部分替代常规交联剂如S或MBT时，巯基苯并咪唑（MBI）可以任选地用作共交联剂。 使用混合的聚硫代吗啉作为交联剂为PMA提供了更好的低温谱（BBR m值）。 使用至少一种烷基多硫化物交联剂使PMA具有改进的PAV老化的DSR结果，并降低了H2S进化。 使用至少一种烷基多硫化物交联剂与MBI一起可以使PMA具有改进的PAV DSR失败温度。

公开(公告)号：US07586765B2

公开(公告)日：2009-09-08

申请号：US11189560

申请日：2005-07-26

申请人： Laurence McGarry ,  William Lee ,  Owen Jiang ,  Horace Liang ,  Lucy Zhong

发明人： Laurence McGarry ,  William Lee ,  Owen Jiang ,  Horace Liang ,  Lucy Zhong

IPC分类号： H02J1/10 ,  G05F1/00

CPC分类号： H02M3/285 ,  H02M3/33592 ,  H02M2001/0032 ,  H02M2001/0087 ,  Y02B70/1475 ,  Y02B70/16

摘要： A switched current power converter includes an input power source, an output terminal, and a plurality of current stages. Each of the current stages includes a converter coupled to the input power source for providing a current and a switch circuit that selectively couples the current in such current stage to the output terminal. A control circuit decouples the input power source from the current stage converters upon detection of a low load condition. Optionally, the power converter includes a low load circuit responsive to the control circuit that selectively couples current to the output terminal during the low load condition.

摘要翻译： 开关电流功率转换器包括输入电源，输出端子和多个电流级。 电流级中的每一个包括耦合到输入电源的转换器，用于提供电流和开关电路，该电流和开关电路将这种当前级中的电流选择性地耦合到输出端。 在检测到低负载条件时，控制电路将输入电源与电流级转换器分离。 可选地，功率转换器包括响应于控制电路的低负载电路，其在低负载条件期间选择性地将电流耦合到输出端子。