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公开(公告)号:US6121235A
公开(公告)日:2000-09-19
申请号:US581662
申请日:1995-12-29
申请人: Wei-Qiang Gao
发明人: Wei-Qiang Gao
CPC分类号: A61K38/185
摘要: Compositions and methods are provided for prophylactic or therapeutic treatment of balance impairments involving neuronal damage, loss, or degeneration, preferably of vestibular ganglion neurons, in an animal by administration of an effective amount of a trkB or trkC agonist, particularly a neurotrophin, more preferably NT-4/5.
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公开(公告)号:US06689744B2
公开(公告)日:2004-02-10
申请号:US09954736
申请日:2001-09-17
申请人: Wei-Qiang Gao , Hartmut Koeppen , Sarajane Ross , Jianyong Shou
发明人: Wei-Qiang Gao , Hartmut Koeppen , Sarajane Ross , Jianyong Shou
IPC分类号: A61K3800
CPC分类号: A61K38/1709 , A61K2039/505 , G01N33/57434 , G01N2500/00
摘要: The present invention is directed to methods of alleviating prostate disorders by activation of the Notch1 receptor. Also provided herein are methods for detecting and diagnosing prostate disorders, wherein the specific disorder is prostate cancer.
摘要翻译: 本发明涉及通过Notch1受体活化来减轻前列腺障碍的方法。 本文还提供了用于检测和诊断前列腺疾病的方法,其中特异性病症是前列腺癌。
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公开(公告)号:US06429196B1
公开(公告)日:2002-08-06
申请号:US09664295
申请日:2000-09-18
申请人: Wei-Qiang Gao
发明人: Wei-Qiang Gao
IPC分类号: A61K3800
CPC分类号: A61K38/185 , Y02A50/473 , A61K2300/00
摘要: Compositions and methods are provided for prophylactic or therapeutic treatment of balance impairments involving neuronal damage, loss, or degeneration, preferably of vestibular ganglion neurons, in an animal by administration of an effective amount of a trkB or trkC agonist, particularly a neurotrophin, more preferably NT-4/5.
摘要翻译: 提供组合物和方法用于通过施用有效量的trkB或trkC激动剂,特别是神经营养因子来预防或治疗涉及动物中神经元损伤,损失或变性(优选前庭神经节神经元)的平衡障碍,更优选地 NT-4/5。
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