公开(公告)号：US06441226B1

公开(公告)日：2002-08-27

申请号：US09467201

申请日：1999-12-20

Applicant: Mohammad Salman ,  Vijay Kumar Kaul ,  J. Suresh Babu ,  Naresh Kumar

Inventor： Mohammad Salman ,  Vijay Kumar Kaul ,  J. Suresh Babu ,  Naresh Kumar

IPC: C07C6116

CPC classification number: C07C403/20 ,  C07C51/09 ,  C07C51/353 ,  C07C2601/16 ,  C07D309/32 ,  C07C57/26

Abstract: The present invention relates to a process for the preparation of 13-cis isomer of Vitamin A acid, commonly known as isotretinoin, in a single step.

Abstract translation: 本发明涉及在单一步骤中制备维生素A酸（通常称为异维A酸）的13-顺式异构体的方法。

公开(公告)号：US4986517A

公开(公告)日：1991-01-22

申请号：US453998

申请日：1989-12-20

Applicant: David A. Ford ,  Gordon J. S. Higginbotham ,  David R. Pugh ,  Naresh Kumar

Inventor： David A. Ford ,  Gordon J. S. Higginbotham ,  David R. Pugh ,  Naresh Kumar

IPC: B22D37/00 ,  B22D39/00 ,  B22D41/05

CPC classification number: B22D41/05 ,  B22D39/00

Abstract: Apparatus for pouring molten metal comprises a water cooled copper crucible 15 which has a recess adjacent its top and a pouring spout 16 positioned in the recess just below the level of the surface of the melt. The recess defines a lip above the spout which helps to ensure that there is a constant pressure head above the spout. Pivotally mounted on the lip, and biased to assume a horizontal position irrespective of the angle of tilt of the crucible is an induction coil 21. The coil induces currents in the surface of the melt and thereby moves the dross away from the pouring spout. The crucible 15 pours into a constant head hopper 22 and the opening and closing of the crucible pouring spout 16 and the angle of tilt of the crucible are controlled to ensure constant pressure head in the hopper.

Abstract translation: 用于浇注熔融金属的设备包括水冷铜坩埚15，其具有邻近其顶部的凹部和位于刚好在熔体表面的水平面下方的凹部中的倾倒口16。 凹口限定出口上方的唇缘，这有助于确保在喷嘴上方有恒定的压力头。 偏心地安装在唇缘上并被偏置以呈现水平位置，而与坩埚的倾斜角度无关的是感应线圈21.线圈在熔体的表面中引起电流，从而将浮渣从倾倒口移出。 将坩埚15倒入恒定的顶部料斗22中，并且控制坩埚倾倒咀16的打开和关闭以及坩埚的倾斜角度以确保料斗中的恒定压力头。