专利检索 cpc:"C07C403/20" 第 1 页

1.

发明授权
2-(alkoxy or aryloxy carbonyl)-4-methyl-6-(2,6,6-trimethylcyclohex-1-enyl)hex-2-enoic acid compounds, its preparation and use 有权

公开(公告)号：US10081613B2

公开(公告)日：2018-09-25

申请号：US15642947

申请日：2017-07-06

申请人： Givaudan S.A.

发明人： Fridtjof Schröder , Urs Mueller , Jürg Daniel Oetiker

IPC分类号： C07D307/92 , C07D307/93 , C07D307/79 , C07C403/20 , C07C69/608 , C07C67/475 , C07C51/38 , C07C67/32 , C07C57/26

CPC分类号： C07D307/92 , C07C51/38 , C07C57/26 , C07C67/32 , C07C67/475 , C07C69/608 , C07C403/20 , C07C2601/14 , C07C2601/16 , C07C2602/48

摘要： Compounds of the formula 1 wherein, R is hydrogen, alkyl or substituted alkyl, aryl or substituted aryl, are useful intermediates in the synthesis of fragrance ingredients such as Ambrox 2

2.

发明申请
STEREOSELECTIVE SYNTHESIS OF 9-CIS.13,14-DIHYDRORETINOIC ACID AND ITS ETHYL ESTERS 审中-公开

公开(公告)号：US20180170867A1

公开(公告)日：2018-06-21

申请号：US15572549

申请日：2016-05-09

申请人： UNIVERSITY OF DEBRECEN , UNIVERSIDADE DE VIGO , UNIVERSITÉ DE STRASBOURG

发明人： Wojciech KREZEL , Ralph RÜHL , Angel R. DE LERA

IPC分类号： C07C403/20 , A61P25/28 , A61P25/24 , C07C67/30 , A23L33/10

CPC分类号： C07C403/20 , A23L33/10 , A23V2002/00 , A61P25/24 , A61P25/28 , C07B2200/07 , C07C67/30 , C07C2601/14 , C07C2601/16

摘要： The retinoid X receptors (RXRs) are ligand-activated transcription factors heterodimerize with a number of nuclear hormone receptors, thereby controlling a variety of physiological processes. The invention relates to novel enantiomer compounds which are derivatives of dihydroretinoic acid, their stereoselective synthesis, to pharmaceutical compositions containing the same and to the use of same in the treatment of diseases.

3.

发明授权
Efficient scalable syntheses of abscisic acid, 8′-acetylene abscisic acid and 8′-cyclopropyl abscisic acid 有权

公开(公告)号：US09725392B2

公开(公告)日：2017-08-08

申请号：US15241564

申请日：2016-08-19

申请人： NATIONAL RESEARCH COUNCIL OF CANADA

发明人： Vishal Jheengut , Ken M. Nelson , Suzanne R. Abrams

IPC分类号： C07C51/09 , C07C46/06 , C07C67/40 , C07C67/327 , C07C403/16

CPC分类号： C07C51/09 , C07C46/06 , C07C67/327 , C07C67/40 , C07C403/16 , C07C403/20 , C07C2601/16 , C07C50/02

摘要： Methods are provided for synthesis of abscisic acid and 8′ analogues thereof (including an enantiopure 8′-acetylene analogue) including methods wherein the previously reported first step of oxidation of 2,6-dimethylphenol (VI) to 2,6-dimethylbenzoquinone, mono ketal (VII) is replaced by a novel two step process comprising (i) oxidation of 2,6-dimethylphenol (VI) using potassium peroxymonosulfate with a catalytic amount of iodobenzene to produce 2,6-dimethylbenzoquinone (XVI) and (ii) ketalization of 2,6-dimethylbenzoquinone (XVI) using ethylene glycol, trimethylorthoformate with a catalytic amount of p-toluenesulfonic acid to produce 2,6-dimethylbenzoquinone, mono ketal (VII).

4.

发明申请
RETINOID DOUBLE CONJUGATE COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS FOR TREATING OF SKIN CONDITIONS 审中-公开
标题翻译：复方双重结合体，其组合物和治疗皮肤病症的方法

公开(公告)号：US20160287507A1

公开(公告)日：2016-10-06

申请号：US15036467

申请日：2014-11-14

申请人： US COSMECEUTECHS LLC

发明人： Joseph A. LEWIS, II

IPC分类号： A61K8/67 , A61Q19/08 , A61Q19/00 , C07C403/20

CPC分类号： A61K8/671 , A61Q19/00 , A61Q19/08 , C07C403/20 , C07C2601/16

摘要： A double conjugate molecule made of a retinoid, an organic acid, particularly an α-hydroxy acid, and an alcohol or acyl group, is provided which is useful in treating skin conditions, particularly aging. The retinoid, organic acid, and alcohol/acyl group are preferably linked via ester bonds.

摘要翻译： 提供由类视色素，有机酸，特别是α-羟基酸，醇或酰基制成的双重共轭分子，其可用于治疗皮肤病症，特别是老化。类视黄醇，有机酸和醇/酰基优选通过酯键连接。

5.

发明申请
2-(ALKOXY OR ARYLOXY CARBONYL)-4-METHYL-6-(2,6,6-TRIMETHYLCYCLOHEX-1- ENYL)HEX-2-ENOIC ACID COMPOUNDS, ITS PREPARATION AND USE 有权

公开(公告)号：US20160002192A1

公开(公告)日：2016-01-07

申请号：US14854705

申请日：2015-09-15

申请人： Givaudan, S.A.

发明人： Fridtjof SCHRÖDER , Urs MUELLER , Jurg Daniel OETIKER

IPC分类号： C07D307/92 , C07C57/26 , C07C51/38 , C07C67/32 , C07C69/608

CPC分类号： C07D307/92 , C07C51/38 , C07C57/26 , C07C67/32 , C07C67/475 , C07C69/608 , C07C403/20 , C07C2601/14 , C07C2601/16 , C07C2602/48

摘要： Compounds of the formula 1 wherein, R is hydrogen, alkyl or substituted alkyl, aryl or substituted aryl, are useful intermediates in the synthesis of fragrance ingredients such as Ambrox 2

6.

发明授权
Retinal derivatives and methods for the use thereof for the treatment of visual disorders 有权

公开(公告)号：US09174936B2

公开(公告)日：2015-11-03

申请号：US13042308

申请日：2011-03-07

申请人： Krzysztof Palczewski , Matthew Batten

发明人： Krzysztof Palczewski , Matthew Batten

IPC分类号： A61K31/225 , A61K31/20 , C07C403/14 , C07C403/10 , C07C403/12 , C07C403/20 , A61K31/22 , A61K31/215

CPC分类号： A61K31/225 , A61K9/0019 , A61K9/0048 , A61K9/0053 , A61K31/215 , A61K31/22 , C07B2200/09 , C07C403/10 , C07C403/12 , C07C403/14 , C07C403/20 , C07C2601/10 , C07C2601/16

摘要： Compositions of and methods for using synthetic retinal derivatives as retinoid replacements and opsin agonists are provided.

7.

发明授权
Methods for making retinoids and uses thereof 有权
标题翻译：维生素A的制备方法及用途

公开(公告)号：US09169190B2

公开(公告)日：2015-10-27

申请号：US13856631

申请日：2013-04-04

申请人： The UAB Research Foundation

发明人： Wayne J. Brouillette , Donald D. Muccio , Venkatram Reddy Atigadda , John M. Ruppert , Susan M. Lobo Ruppert

IPC分类号： C07C205/00 , C07C229/00 , C07C59/40 , C07C63/333 , C07C61/00 , A61K31/20 , A61K31/195 , C07C57/50 , C07C29/14 , C07C45/29 , C07C45/30 , C07C45/51 , C07C45/61 , C07C45/67 , C07C45/68 , C07C47/238 , C07C49/403 , C07C49/417 , C07C49/603 , C07C49/683 , C07C49/713 , C07C49/753 , C07C51/09 , C07C67/343 , C07C403/08 , C07C403/14 , C07C403/20 , C07D311/96 , C12C11/02 , C07C57/26

CPC分类号： A61K31/202 , A61K9/0014 , A61K45/06 , C07B2200/09 , C07C29/14 , C07C45/29 , C07C45/292 , C07C45/30 , C07C45/513 , C07C45/61 , C07C45/673 , C07C45/68 , C07C47/238 , C07C49/403 , C07C49/417 , C07C49/603 , C07C49/683 , C07C49/713 , C07C49/753 , C07C51/09 , C07C57/26 , C07C57/50 , C07C67/343 , C07C403/08 , C07C403/14 , C07C403/20 , C07C2601/02 , C07C2601/14 , C07C2601/16 , C07C2602/10 , C07C2602/28 , C07D311/96 , C12C11/02 , C07C33/16 , C07C69/618

摘要： Described herein are methods for making retinoids. Also described herein are retinoids and methods of use thereof.

摘要翻译： 本文描述了制备类视黄醇的方法。本文还描述了类视黄醇及其使用方法。

8.

发明申请
Cyclohexenone Compositions and Process for Making Thereof 有权
标题翻译：环己烯酮组合物及其制备方法

公开(公告)号：US20150018567A1

公开(公告)日：2015-01-15

申请号：US14184954

申请日：2014-02-20

申请人： Golden Biotechnology Corporation

发明人： Sheng-Yung Liu , Wu-Che Wen , Chih-Ming Chen , Hsiu-Yi Cheng

IPC分类号： C07C49/753 , C07C45/00 , C07D307/20

CPC分类号： C07C403/02 , C07C45/00 , C07C45/61 , C07C49/753 , C07C403/20 , C07D307/20 , C07D307/33

摘要： Provided herein are processes of preparing cyclohexenone compounds useful for cancer treatments and/or diseases.

摘要翻译： 本文提供了制备用于癌症治疗和/或疾病的环己烯酮化合物的方法。