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公开(公告)号:US11434195B2
公开(公告)日:2022-09-06
申请号:US16632721
申请日:2018-07-20
Inventor: Stanislav Igorevich Svetlov
IPC: C07C217/28 , A61K31/133
Abstract: Compounds, pharmaceutical compositions, and methods for treating cancer, in particular brain cancer, are provided, including amphiphilic fatty acid/alcohol ethers (AIPs) comprising endocannabinoid and FABP motifs covalently linked to a beta-adrenoreceptor antagonist motif in one molecule. The invention includes methods for inhibiting growth of brain cancer cells by contacting the compound(s) with brain cancer cells. The invention provides a method for treating both brain cancer and brain cancer metastases, and for suppression of regrowth of brain cancer cells after radiation, surgical treatment, or chemotherapy of brain cancer. The invention also comprises an optimized chemical synthesis of the AIP compounds and methods of using the compounds, alone or in combination with another agent, for suppressing the growth of brain cancer cells, and enhancing survival of normal CNS cells, or improving recuperation from radiation, surgical or chemotherapy.
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公开(公告)号:US20220274170A1
公开(公告)日:2022-09-01
申请号:US17664165
申请日:2022-05-19
Inventor: MICHELE VIOLA MANUEL , HUNTER B. HENDERSON , ORLANDO RIOS , GERARD M. LUDTKA
IPC: B22F9/06 , C22C1/10 , C25D1/00 , C25D15/00 , B22F1/00 , H01F1/047 , H01F1/44 , H05B6/36 , B22F1/07 , B22F1/054
Abstract: Disclosed herein is a method comprising disposing a container containing a metal and/or ferromagnetic solid and abrasive particles in a static magnetic field; where the container is surrounded by an induction coil; activating the induction coil with an electrical current, to heat up the metallic or ferromagnetic solid to form a fluid; generating sonic energy to produce acoustic cavitation and abrasion between the abrasive particles and the container; and producing nanoparticles that comprise elements from the container, the metal and/or the ferromagnetic solid and the abrasive particles. Disclosed herein too is a composition comprising first metal or a first ceramic; and particles comprising carbides and/or nitrides dispersed therein. Disclosed herein too is a composition comprising nanoparticles comprising chromium carbide, iron carbide, nickel carbide, γ-Fe and magnesium nitride.
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公开(公告)号:US20220234103A1
公开(公告)日:2022-07-28
申请号:US17694162
申请日:2022-03-14
Inventor: Wei David Wei , Yueming Zhai
Abstract: In one aspect, the present disclosure pertains to methods of making various noble metal nanoprisms, e.g., gold nanoprisms. In various aspects, the methods can comprise incubating, under dark conditions, a growth solution comprising: (a) a plurality of gold seed structures; (b) a gold precursor, and (c) a photocatalytic intermediary, such that during the incubating step multiply-twinned gold seed structures in the growth solution are preferentially enlarged. The disclosed methods can comprise separating the multiply-twinned gold seed structures from the growth solution based upon the size of the gold seed structures to produce an enriched growth solution. In some aspects, the methods comprise irradiating the enriched growth solution to produce the gold nanoprisms. In some aspects, the disclosed nanoprisms comprise silver.
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公开(公告)号:US20220200351A1
公开(公告)日:2022-06-23
申请号:US17556352
申请日:2021-12-20
Inventor: Patrick RIEHL , Chin-Wei CHANG
Abstract: A contactless charging drawer for smart garments using magnetic coupling links. A frame with a primary coil creates a magnetic field which couples with a secondary coil disposed a drawer. Smart garments, or any device, can then be safely charged in the drawer. The combination provides for a wireless power charging environment while adding an extra degree of freedom in impedance transformation without the need for electrical contacts to the drawer.
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公开(公告)号:US20220185950A1
公开(公告)日:2022-06-16
申请号:US17607522
申请日:2020-04-30
Inventor: Adam S. Veige , Vineet K. Jakhar
Abstract: Provided herein are catalysts for polymerization of alkenes to cyclic poly(alkenes), and methods of making and using the same.
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公开(公告)号:US11344846B2
公开(公告)日:2022-05-31
申请号:US16423812
申请日:2019-05-28
Inventor: Timothy Townsend , Ronald Bishop , David Wood , James Lloyd
Abstract: Embodiments of the present disclosure provide for systems for removing contaminants from a leachate, methods of removing contaminants from a leachate, and the like.
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公开(公告)号:US20220156366A1
公开(公告)日:2022-05-19
申请号:US17525176
申请日:2021-11-12
IPC: G06F21/55 , H04L12/933 , G06F7/58 , G06F15/78 , H04L9/06
Abstract: The present disclosure describes digital watermark detection systems and methods. In one such system, a plurality of intellectual property cores are integrated on a system-on-chip, such that the intellectual property cores comprise a first intellectual property core and a second intellectual property core. The system further includes a first network interface connected to the first intellectual property core that can encode a first digital watermark into a packet stream designated for the second intellectual property core. The system further includes a second network interface connected to the second intellectual property core that can receive the packet stream and decode the packet stream to generate a second digital watermark. The second network interface is further configured to perform a validation test on the packet stream and deliver the packet stream to the second intellectual property core when the first digital watermark is determined to match the second digital watermark.
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88.
公开(公告)号:US20220155486A1
公开(公告)日:2022-05-19
申请号:US17327129
申请日:2021-05-21
Applicant: University of Florida Research Foundation, Inc. , Clarkson University , Woods Hole Oceanographic Institution
Inventor: Forrest J. Masters , Pedro L. Fernandez-Caban , Brian M. Phillips , Christopher C. Ferraro , Britt Raubenheimer , Wei-Ting Lu
Abstract: The present disclosure describes various embodiments of systems, apparatuses, and methods for large-scale processing of weather-related data. For one such system, the system comprises a database of weather-related data providing from a plurality of weather monitoring stations and a plurality of interconnected processors for coordinating a data processing job for processing a set of input weather-related data from the database. Accordingly, the input data comprises sensor data from an array of weather monitoring stations positioned on an open shoreline during a hydrodynamic event, weather model data for the hydrodynamic event, and at least one of air-craft reconnaissance data or satellite reconnaissance data regarding the hydrodynamic event, wherein the plurality of interconnected processors are configured to assimilate the input data and generate, using machine learning, an improved weather prediction model for the hydrodynamic event. Other systems, apparatuses, and methods are also provided.
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89.
公开(公告)号:US20220127421A1
公开(公告)日:2022-04-28
申请号:US17434512
申请日:2020-03-05
Inventor: Anthony B. Brennan , Vishal Vignesh
IPC: C08G71/04 , C08F220/56 , C08F222/10 , C08F220/22
Abstract: Disclosed herein is a composition comprising a water soluble monomer or polymer; a fluorine functionalized acrylate; and a non-isocyanate urethane acrylate. Disclosed herein is a method comprising mixing a water soluble monomer or polymer, a fluorine functionalized acrylate and a non-isocyanate urethane acrylate to form a composition; and curing the composition.
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公开(公告)号:US11309736B2
公开(公告)日:2022-04-19
申请号:US16735437
申请日:2020-01-06
Inventor: David Patrick Arnold , Shuo Cheng , Vinod Reddy Challa
Abstract: Wireless power transmission (WPT) systems are provided. For example, the WPT system can use one or more power transmitting coils and a receiver for electromagnetically coupled wireless power transfer. The electrodynamic receiver can be in the form of an electrodynamic transducer where a magnet is allowed to oscillate near a receiving coil to induce a voltage in the receiving coil, a piezoelectric transducer where the magnet causes a vibrating structure with a piezoelectric layer to move, an electrostatic transducer where movement of the magnet causes a capacitor plate to move, or a combination thereof. An alternating magnetic field from the transmitting coil(s) excites the magnet in the receiver into mechanical resonance. The vibrating magnet then functions similar to an energy harvester to induce voltage/current on an internal coil, piezoelectric material, or variable capacitor. Embodiments utilize magnetic coupling and electromechanical resonance for safe, spatially distributed, low-frequency power delivery to portable devices.
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