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    Process for obtaining extracts from animal tissues
    1.
    发明授权
    Process for obtaining extracts from animal tissues 失效
    从动物组织获取提取物的方法

    公开(公告)号：US3676551A

    公开(公告)日：1972-07-11

    申请号：US3676551D

    申请日：1969-10-03

    申请人： LAB ALBERT ROLLAND

    发明人： THUILLIER YVONNE

    IPC分类号： A61K35/12 ,  A61K38/43 ,  A61K17/00

    CPC分类号： A61K35/34 ,  A61K35/22 ,  A61K35/26 ,  A61K35/32 ,  A61K35/39 ,  A61K35/42 ,  A61K36/064

    摘要： Extracts of animal organs, useful in opotherapy, are prepared by removing from the organ aseptically collected immediately after slaughtering the animal, foreign matter, debris and fat. The remainder is then very rapidly frozen to about a temperature of 78* C. and maintained at a temperature of about -20* C. Thereupon, the organ is crushed at a temperature of about 2* C. and subjected to moderate digestion at room temperature by activated trypsin. By removing insoluble matter a clear solution is obtained. Euglobulins present in the solution are removed by affixing on an insoluble sulfate which is thereupon removed and the resulting solution is clarified. Finally, the clarified solution is rapidly freeze-dried at a temperature of about -80* C.

    摘要翻译： 通过从屠宰动物，异物，碎片和脂肪后立即无菌收集的器官中除去，可以制备用于药物治疗的动物器官的提取物。 然后将其余部分迅速冷冻至约-78℃的温度，并保持在约-20℃的温度。随后，将器官在约2℃的温度下压碎，并在 活性胰蛋白酶的室温。 通过除去不溶物，得到澄清溶液。 通过粘附在不溶性硫酸盐上去除存在于溶液中的特异球蛋白，然后将其去除并将所得溶液澄清。 最后，将澄清溶液在约-80℃的温度下快速冷冻干燥