公开(公告)号：US20160158409A1

公开(公告)日：2016-06-09

申请号：US14991657

申请日：2016-01-08

申请人： TEKNIMED SAS ,  L' UNIVERSITE PAUL SABATIER (TOULOUSE III) ,  LE CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE

发明人： Alain LEONARD ,  Stéphane GONCALVES ,  Juliette FITREMANN ,  Ariane BERCIER

IPC分类号： A61L27/12 ,  A61L27/18

CPC分类号： A61L27/12 ,  A61L24/02 ,  A61L27/18 ,  A61L2430/02

摘要： Calcium phosphate-based formulation for bone filling, comprising at least one adjuvant giving adhesion properties, wherein the at least one adjuvant is selected from the saccharide head surfactant group. The bone cement is characterized by adhesive properties particularly advantageous facilitating the setting of the cement and offering a better containment of the bone-cement or bone-cement-prosthesis interface.

摘要翻译： 用于骨填充的基于磷酸钙的制剂，其包含至少一种赋予粘附性质的佐剂，其中所述至少一种佐剂选自糖头部表面活性剂组。 骨粘固剂的特征在于粘合性能特别有利于促进水泥的凝固并且提供更好地容纳骨水泥或骨水泥 - 假体界面。

公开(公告)号：US08536243B2

公开(公告)日：2013-09-17

申请号：US12766530

申请日：2010-04-23

申请人： Alain Leonard ,  Cyril Sender ,  Claudine Lavergne ,  Benoît Donazzon

发明人： Alain Leonard ,  Cyril Sender ,  Claudine Lavergne ,  Benoît Donazzon

IPC分类号： A61F2/28

CPC分类号： A61L24/06 ,  A61L2430/02 ,  C08L33/12

摘要： The invention relates to a system for preparing a polymerized bone cement, including two components reacting with each other when they are mixed to form a solid polymer material. The first component may include a biocompatible acrylic polymer and an initiator capable of initiating a polymerization reaction. The second component may include a monomer capable of dissolving an acrylic polymer, a polymerization activator and a polymerization inhibitor, system in which the second component also includes a biocompatible acrylic polymer dissolved in said monomer, identical or different from the polymer of the first component with an average molar mass greater than 1,000,000 g/mol and a residual initiator content of less than 0.1% to form a gel with determined viscosity. Another object of the invention is a composition designed to constitute the second component of as system used to prepare such cement.

摘要翻译： 本发明涉及一种制备聚合骨水泥的系统，包括两种组分在混合形成固体聚合物材料时彼此反应。 第一组分可以包括生物相容的丙烯酸聚合物和能够引发聚合反应的引发剂。 第二组分可以包括能够溶解丙烯酸聚合物，聚合活化剂和阻聚剂的体系，其中第二组分还包括溶解在所述单体中的生物相容性丙烯酸聚合物，与第一组分的聚合物相同或不同， 平均摩尔质量大于1,000,000g / mol，残留引发剂含量小于0.1％以形成具有确定粘度的凝胶。 本发明的另一个目的是设计成构成用于制备这种水泥的系统的第二组分的组合物。