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    Device for the injection of bone cement, comprising an overpressure locking system
    3.
    发明授权
    Device for the injection of bone cement, comprising an overpressure locking system 有权
    用于注射骨水泥的装置，包括超压锁定系统

    公开(公告)号：US08876834B2

    公开(公告)日：2014-11-04

    申请号：US13697820

    申请日：2011-11-16

    申请人： Freddy Bonnin ,  Alain Leonard

    发明人： Freddy Bonnin ,  Alain Leonard

    IPC分类号： A61B17/58 ,  A61B17/60 ,  A61F2/00 ,  A61B17/88

    CPC分类号： A61B17/8822 ,  A61B17/8819 ,  A61B17/8827

    摘要： The invention relates to a device for the injection of a bone cement. The invention comprises a container provided with one end including an outlet and a second end that receives a piston. The piston is moved by means of an injection screw that projects from the container body and engages with gripping means comprising injection screw rotation means that can self-lock depending on the pressure exerted inside the container body, said rotation means comprising a handle which is provided with a passage that receives the injection screw and which is hinged thereto by means of a pair of male/female disks. One disk is known as the drive disk and moves integrally with the rotation movements of the handle, while the other disk is known as the driven disk, said drive disk coming into contact with the driven disk in response to a compressive force exerted on the distal part of the injection screw.

    摘要翻译： 本发明涉及一种用于注射骨水泥的装置。 本发明包括一个容器，该容器设置有一个端部，其一端包括一个出口和一个接收活塞的第二端。 活塞通过从容器主体突出的注射螺杆移动，并与包括注射螺杆旋转装置的夹持装置接合，该装置可以根据施加在容器主体内的压力自行锁定，所述旋转装置包括提供的手柄 具有接收注射螺杆并且通过一对阳/阴盘铰接到其上的通道。 一个盘被称为驱动盘并与手柄的旋转运动一体移动，而另一个盘被称为从动盘，所述驱动盘响应于施加在远端的压缩力而与从动盘接触 部分注射螺丝。

    RESORBABLE AND RADIOPAQUE DEVICE FOR BONE FIXATION
    4.
    发明申请
    RESORBABLE AND RADIOPAQUE DEVICE FOR BONE FIXATION 有权
    用于骨固定的可变和放射性装置

    公开(公告)号：US20140039562A1

    公开(公告)日：2014-02-06

    申请号：US13603544

    申请日：2012-09-05

    申请人： Alain LEONARD ,  Carole LEONARD ,  Cyril SENDER ,  Olivier LIGNON ,  Gautier HALBIN ,  Nouredine SAHRAOUI

    发明人： Alain LEONARD ,  Carole LEONARD ,  Cyril SENDER ,  Olivier LIGNON ,  Gautier HALBIN ,  Nouredine SAHRAOUI

    IPC分类号： A61B17/80

    CPC分类号： A61L31/127 ,  A61L31/128 ,  A61L31/14 ,  A61L31/148 ,  A61L31/18 ,  A61L2430/02 ,  C08L67/04 ,  C08L69/00

    摘要： An osteosynthesis device that is both resorbable and radiopaque, produced using gradually degrading materials, includes at least one plate and a set of screws made of resorbable material, in which the plate consists of a composite mixture including i) a resorbable polymer or copolymer compound and ii) an inorganic filler that consists of at least one resorbable ceramic. The screws can be made of resorbable polymer, or of a composite mixture with at least one resorbable ceramic. The device is totally resorbable and radiopaque, and it offers a high level of safety, ensuring a strong and durable fixation of the screws to the plate and in the bone during the entire period needed for bone uniting.

    摘要翻译： 使用逐渐降解材料生产的可再吸收和不透射线的骨接合装置包括至少一个板和一组由可再吸收材料制成的螺钉，其中该板由复合混合物组成，复合混合物包括i）可再吸收的聚合物或共聚物化合物和 ii）由至少一种可吸收陶瓷组成的无机填料。 螺钉可以由可再吸收的聚合物制成，或者与至少一种可吸收陶瓷的复合混合物制成。 该装置是完全可吸收的和不透射线的，它提供了高水平的安全性，确保在骨骼联合所需的整个时间段内将螺钉牢固耐用地固定在板和骨骼上。

    Two-component system for bone cement
    5.
    发明授权
    Two-component system for bone cement 有权
    骨水泥双组分体系

    公开(公告)号：US08536243B2

    公开(公告)日：2013-09-17

    申请号：US12766530

    申请日：2010-04-23

    申请人： Alain Leonard ,  Cyril Sender ,  Claudine Lavergne ,  Benoît Donazzon

    发明人： Alain Leonard ,  Cyril Sender ,  Claudine Lavergne ,  Benoît Donazzon

    IPC分类号： A61F2/28

    CPC分类号： A61L24/06 ,  A61L2430/02 ,  C08L33/12

    摘要： The invention relates to a system for preparing a polymerized bone cement, including two components reacting with each other when they are mixed to form a solid polymer material. The first component may include a biocompatible acrylic polymer and an initiator capable of initiating a polymerization reaction. The second component may include a monomer capable of dissolving an acrylic polymer, a polymerization activator and a polymerization inhibitor, system in which the second component also includes a biocompatible acrylic polymer dissolved in said monomer, identical or different from the polymer of the first component with an average molar mass greater than 1,000,000 g/mol and a residual initiator content of less than 0.1% to form a gel with determined viscosity. Another object of the invention is a composition designed to constitute the second component of as system used to prepare such cement.

    摘要翻译： 本发明涉及一种制备聚合骨水泥的系统，包括两种组分在混合形成固体聚合物材料时彼此反应。 第一组分可以包括生物相容的丙烯酸聚合物和能够引发聚合反应的引发剂。 第二组分可以包括能够溶解丙烯酸聚合物，聚合活化剂和阻聚剂的体系，其中第二组分还包括溶解在所述单体中的生物相容性丙烯酸聚合物，与第一组分的聚合物相同或不同， 平均摩尔质量大于1,000,000g / mol，残留引发剂含量小于0.1％以形成具有确定粘度的凝胶。 本发明的另一个目的是设计成构成用于制备这种水泥的系统的第二组分的组合物。

    ARTICULAR IMPLANT COMPRISING AT LEAST TWO CAVITIES
    6.
    发明申请
    ARTICULAR IMPLANT COMPRISING AT LEAST TWO CAVITIES 审中-公开
    包括至少两个CAVITIES的特殊植被

    公开(公告)号：US20110015754A1

    公开(公告)日：2011-01-20

    申请号：US12504405

    申请日：2009-07-16

    申请人： Alain LEONARD ,  Freddy Bonnin

    发明人： Alain LEONARD ,  Freddy Bonnin

    IPC分类号： A61F2/32

    摘要： The present invention relates to a device for the replacement of a permanent articular prosthesis at an implant site, comprising a stem (1) suited to being fixed to a support bone, connected to a head (2) suited to being arranged in an articular area, comprising at least two different cavities (3) with leak tight walls formed at the head (2) made of a thermoplastic material, said cavities (3) emerging at the surface of the device in contact with the implant site, and means for separating (4) cavities (3) from the implant site, enabling the diffusion of a liquid on either side of said separating means.

    摘要翻译： 本发明涉及一种用于在植入部位替换永久性关节假体的装置，包括适于固定到支撑骨的杆（1），所述杆（1）连接到适于布置在关节区域中的头部（2） ，其包括形成在由热塑性材料制成的头部（2）处的泄漏壁的至少两个不同的空腔（3），所述空腔（3）出现在与植入部位接触的装置的表面处，以及用于分离的装置 （4）来自植入位置的腔（3），使得能够在所述分离装置的任一侧上扩散液体。

    Temporary implant incorporating two active ingredients
    7.
    发明授权
    Temporary implant incorporating two active ingredients 有权
    临时植入物包含两种活性成分

    公开(公告)号：US08449621B2

    公开(公告)日：2013-05-28

    申请号：US11712891

    申请日：2007-03-02

    申请人： Alain Leonard ,  Claudine Lavergne ,  Jean-françois Oglaza

    发明人： Alain Leonard ,  Claudine Lavergne ,  Jean-françois Oglaza

    IPC分类号： A61F2/40

    CPC分类号： A61F2/30 ,  A61F2/36 ,  A61F2/3662 ,  A61F2/4637 ,  A61F2002/3021 ,  A61F2002/30332 ,  A61F2002/30616 ,  A61F2002/30672 ,  A61F2002/30677 ,  A61F2002/3611 ,  A61F2002/3625 ,  A61F2002/3631 ,  A61F2002/365 ,  A61F2002/4681 ,  A61F2220/0033 ,  A61F2230/0067 ,  A61F2310/00011 ,  A61F2310/00353

    摘要： A ready-for-use polymer cement spacer device for the replacement of a permanent joint prosthesis during a two-stage replacement, includes a shank includes for attachment for placing to the supporting bone and a head in the joint region. The spacer device includes two complementary members incorporating rigid members for assembly between them, the first member being loaded with a first active substance and the second member being loaded with a second active substance. The first and second active substances are preferably antibiotics, selected from gentamycin, trobamycin, vancomycin, erythromycin, fucidin, tetracycline or other suitable antibiotics. The temporary joint implant maintains a suitable space for the time necessary for the operation of replacing a permanent prosthesis to prevent tissues from occupying the space released by removal of the permanent prosthesis and ensures effective treatment of resistant infections by local treatment of the joint area through at least two different active substances.

    摘要翻译： 一种用于在两级更换期间替换永久性关节假体的即用型聚合物水泥间隔器装置，包括用于附接到支撑骨中以及在接合区域中的头部的柄部。 间隔装置包括两个互补构件，其中包括用于在它们之间组装的刚性构件，第一构件装载有第一活性物质，第二构件装载有第二活性物质。 第一和第二活性物质优选为选自庆大霉素，特布菌霉素，万古霉素，红霉素，fucidin，四环素或其他合适的抗生素的抗生素。 临时关节植入物保持适当的空间，用于更换永久假体的操作所需的时间，以防止组织占据通过移除永久性假体而释放的空间，并通过局部治疗接合区域通过在 至少两种不同的活性物质。

    Polymer cement for percutaneous vertebroplasty and methods of using and making same
    8.
    发明授权
    Polymer cement for percutaneous vertebroplasty and methods of using and making same 有权
    用于经皮椎体成形术的聚合物水泥及其使用和制造方法

    公开(公告)号：US08153704B2

    公开(公告)日：2012-04-10

    申请号：US11757427

    申请日：2007-06-04

    申请人： Claudine Lavergne ,  Alain Leonard

    发明人： Claudine Lavergne ,  Alain Leonard

    IPC分类号： A61L27/18 ,  A61F2/00

    CPC分类号： A61L24/0094 ,  A61L27/446 ,  A61L2430/02 ,  C08L33/12

    摘要： The invention provides a fluid cement for medical use for bone reconstruction, in particular for filling the vertebral body, and a binary composition which is intended for the preparation of such a cement. The invention also provides a device for conditioning the binary composition, and a method of preparing a bone cement from a binary composition. The fluid cement according to the invention comprises: a) approximately 60% to 85% by weight of a polymer comprising a polymethylmethacrylate and a methylmethacrylate monomer and b) approximately from 15 to 40% by weight of a radio-opaque composition. Preferably, the radio-opaque composition comprises a radio-opacifier, such as barium sulfate and zirconium dioxide, in a mixture with a calcium phosphate, for example apatite hydroxide.

    摘要翻译： 本发明提供一种用于医学用途的用于骨重建，特别是用于填充椎体的流体粘合剂，以及用于制备这种水泥的二元组合物。 本发明还提供了一种用于调节二元组合物的装置，以及从二元组合物制备骨粘固剂的方法。 根据本发明的流体粘合剂包括：a）约60％至85％重量的包含聚甲基丙烯酸甲酯和甲基丙烯酸甲酯单体的聚合物，以及b）约15至40重量％的不透射线组合物。 优选地，不透射线组合物包含与磷酸钙（例如磷灰石氢氧化物）的混合物中的放射性遮光剂，例如硫酸钡和二氧化锆。