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公开(公告)号:US20230036392A1
公开(公告)日:2023-02-02
申请号:US17428416
申请日:2020-02-04
发明人: Sunyoung Kim
IPC分类号: G01N33/573
摘要: This invention is directed to compositions and methods to detect and treat gastrointestinal diseases.
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公开(公告)号:US11285191B2
公开(公告)日:2022-03-29
申请号:US16320586
申请日:2017-07-26
IPC分类号: A61K38/20 , A61K39/012 , A61K39/04 , A61K39/21 , A61K39/295 , C07K14/54 , A61P37/04 , A61P31/18 , A61K38/17 , A61K39/00
摘要: Disclosed are compositions and methods for stimulating immune responses. More particularly, these compositions and methods involve the use of an inhibitor of IL-25 function and an immune stimulator that stimulates an immune response to a target antigen for stimulating protective or therapeutic immune responses to a target antigen. The compositions and methods of the present invention are particularly useful in the prevention and treatment of infections and cancers.
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公开(公告)号:US20210393407A1
公开(公告)日:2021-12-23
申请号:US17281889
申请日:2019-10-01
发明人: Giovanni SOLITRO
摘要: This invention is directed to structural units and bioscaffolds that comprise the same for in vivo use.
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公开(公告)号:US20210379075A1
公开(公告)日:2021-12-09
申请号:US17322606
申请日:2021-05-17
申请人: The Board of Supervisors of Louisiana State University and Agricultural and Mechanical College , University of Alcala de Henares , South Rampart Pharma, LLC
发明人: Nicolas Bazan , Hernan Bazan , Julio Alvarez-Builla Gomez , Dennis Paul , Carolina Burgos Garcia
IPC分类号: A61K31/5375 , A61P23/00 , A61K31/18 , A61K31/40 , A61K31/4402 , A61K31/495 , A61K45/06 , A61P29/00 , C07C311/19
摘要: This invention is directed to compositions, methods and kits that can be used for the treatment or amelioration of pain and fever.
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公开(公告)号:US20210236621A1
公开(公告)日:2021-08-05
申请号:US17259352
申请日:2019-07-09
申请人: Arizona Board of Regents on Behalf of The University of Arizona , The University of North Carolina at Chapel Hill , The Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
发明人: Felicia Goodrum , Nathaniel Moorman , Jeremy Kamil
摘要: Viral promoters and compositions and methods of use thereof are provided. Compositions include viruses with impaired ability to reactivate from latency, and pharmaceutical compositions and method of use thereof. The genome of the viruses include one or more mutations that reduce expression from one or more promoters that regulate expression of viral genes during reactivation from latency. The mutation(s) are typically in a region of the viral genome that includes (i) promoter elements of the iP1 promoter of human cytomegalovirus, or the sequence of another virus corresponding thereto (e.g., an iP1 promoter homolog); (ii) promoter elements of the iP2 promoter of human cytomegalovirus, or sequence of another virus corresponding thereto (e.g., an iP2 promoter homolog); or (iii) a combination thereof. In some embodiments the virus encodes one or more heterologous antigens. The viruses can be used as vaccines to induce prophylactic and therapeutic immune responses in subjects in need thereof.
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公开(公告)号:US20200330522A1
公开(公告)日:2020-10-22
申请号:US16833099
申请日:2020-03-27
发明人: Frank Ho Pak Lau , Ian Hodgdon , Michael Cook
摘要: A method of preventing or reducing the occurrence and/or development of a hernia within a subject at risk of developing a hernia includes implanting a graft material in contact with an opening in an abdominal wall. The graft material promotes healing of the abdominal wall and includes placental or placental derived tissue.
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公开(公告)号:US20200330405A1
公开(公告)日:2020-10-22
申请号:US16610382
申请日:2018-05-01
IPC分类号: A61K31/137 , A61K31/404 , A61K31/48
摘要: This invention features compositions, methods, and kits for treating conditions associated with pathological ocular neovascularization, reducing scarring in the eye, treating dry eye, treating macular degeneration, and treating keratitis by administering a serotonin receptor agonist.
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公开(公告)号:USPP32021P2
公开(公告)日:2020-07-28
申请号:US16350993
申请日:2019-02-08
摘要: A new variety of sweetpotato, identified as ‘LA13-81’, is disclosed having disease resistance to both Fusarium wilt and Streptomyces soil rot; an orange flesh storage root and deep red-purple skin, and high yield characteristics.
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公开(公告)号:USPP32003P2
公开(公告)日:2020-07-21
申请号:US16350990
申请日:2019-02-08
发明人: Don R. LaBonte
摘要: A new variety of sweetpotato, identified as ‘LA17-54’, is disclosed having disease resistance to Fusarium wilt; an orange flesh, red-copper skin storage root and attractive purple, red-hued and green leaves with purple venation and purple vines.
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公开(公告)号:USPP31970P2
公开(公告)日:2020-07-14
申请号:US16350984
申请日:2019-02-08
摘要: A new variety of sweetpotato, identified as ‘LA08-21P’, is disclosed having resistance to both Fusarium wilt and southern root knot nematode; a light purple-banded flesh and deep-purple skin, and moderately high yield characteristics.
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