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公开(公告)号：US20160023904A1
公开(公告)日：2016-01-28
申请号：US14444845
申请日：2014-07-28
申请人： Massachusetts Institute of Technology , University of Michigan, The Board of Regents Acting For and On behalf of the C/O Technology Man
CPC分类号： C01B31/0233 , B81C1/00626 , C01B32/162 , C01B2202/02 , C01B2202/06 , C01B2202/08 , C01B2202/20 , C01B2202/36 , C23C16/52
摘要： The present invention generally relates to articles comprising microstructures and methods for forming microstructures. The microstructures may be mechanically coupled to impart complex three dimensional shapes. For example, one or more microstructures may be grown on a substrate at different average growth rates, resulting in curved microstructures.
摘要翻译： 本发明一般涉及包含微结构的制品和用于形成微结构的方法。 微结构可以机械耦合以赋予复杂的三维形状。 例如，一个或多个微结构可以以不同的平均生长速率在衬底上生长，导致弯曲的微结构。
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公开(公告)号：US08545791B2
公开(公告)日：2013-10-01
申请号：US12817818
申请日：2010-06-17
申请人： Desiree L. Plata , Philip S. Gschwend , Anastasios John Hart , Eric R. Meshot , Christopher M. Reddy
发明人： Desiree L. Plata , Philip S. Gschwend , Anastasios John Hart , Eric R. Meshot , Christopher M. Reddy
IPC分类号： D01C5/00
CPC分类号： C01B31/0226 , B82Y30/00 , B82Y40/00 , C01B32/16 , C01B32/18
摘要： The present invention relates to the formation and processing of nanostructures including nanotubes. Some embodiments provide processes for nanostructure growth using relatively mild conditions (e.g., low temperatures). In some cases, methods of the invention may improve the efficiency (e.g., catalyst efficiency) of nanostructure formation and may reduce the production of undesired byproducts during nanostructure formation, including volatile organic compounds and/or polycylic aromatic hydrocarbons. Such methods can both reduce the costs associated with nanostructure formation, as well as reduce the harmful effects of nanostructure fabrication on environmental and public health and safety.
摘要翻译： 本发明涉及包括纳米管的纳米结构的形成和加工。 一些实施方案使用相对温和的条件（例如低温）提供纳米结构生长的方法。 在一些情况下，本发明的方法可以提高纳米结构形成的效率（例如，催化剂效率），并且可以减少纳米结构形成期间不期望的副产物的产生，包括挥发性有机化合物和/或多环芳烃。 这些方法既可降低与纳米结构形成相关的成本，又能减少纳米结构制造对环境和公共卫生与安全的有害影响。
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公开(公告)号：US20140134093A1
公开(公告)日：2014-05-15
申请号：US13975745
申请日：2013-08-26
发明人： Desiree L. Plata , Philip S. Gschwend , Anastasios John Hart , Eric R. Meshot , Christopher M. Reddy
IPC分类号： C01B31/02
CPC分类号： C01B31/0226 , B82Y30/00 , B82Y40/00 , C01B32/16 , C01B32/18
摘要： The present invention relates to the formation and processing of nanostructures including nanotubes. Some embodiments provide processes for nanostructure growth using relatively mild conditions (e.g., low temperatures). In some cases, methods of the invention may improve the efficiency (e.g., catalyst efficiency) of nanostructure formation and may reduce the production of undesired byproducts during nanostructure formation, including volatile organic compounds and/or polycylic aromatic hydrocarbons. Such methods can both reduce the costs associated with nanostructure formation, as well as reduce the harmful effects of nanostructure fabrication on environmental and public health and safety.
摘要翻译： 本发明涉及包括纳米管的纳米结构的形成和加工。 一些实施方案使用相对温和的条件（例如低温）提供纳米结构生长的方法。 在一些情况下，本发明的方法可以提高纳米结构形成的效率（例如，催化剂效率），并且可以减少纳米结构形成期间不期望的副产物的产生，包括挥发性有机化合物和/或多环芳烃。 这些方法既可降低与纳米结构形成相关的成本，又能减少纳米结构制造对环境和公共卫生与安全的有害影响。
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公开(公告)号：US20110038784A1
公开(公告)日：2011-02-17
申请号：US12817818
申请日：2010-06-17
申请人： Desiree L. Plata , Philip M. Gschwend , Anastasios John Hart , Eric R. Meshot , Christopher M. Reddy
发明人： Desiree L. Plata , Philip M. Gschwend , Anastasios John Hart , Eric R. Meshot , Christopher M. Reddy
CPC分类号： C01B31/0226 , B82Y30/00 , B82Y40/00 , C01B32/16 , C01B32/18
摘要： The present invention relates to the formation and processing of nanostructures including nanotubes. Some embodiments provide processes for nanostructure growth using relatively mild conditions (e.g., low temperatures). In some cases, methods of the invention may improve the efficiency (e.g., catalyst efficiency) of nanostructure formation and may reduce the production of undesired byproducts during nanostructure formation, including volatile organic compounds and/or polycylic aromatic hydrocarbons. Such methods can both reduce the costs associated with nanostructure formation, as well as reduce the harmful effects of nanostructure fabrication on environmental and public health and safety.
摘要翻译： 本发明涉及包括纳米管的纳米结构的形成和加工。 一些实施方案使用相对温和的条件（例如低温）提供纳米结构生长的方法。 在一些情况下，本发明的方法可以提高纳米结构形成的效率（例如，催化剂效率），并且可以减少纳米结构形成期间不期望的副产物的产生，包括挥发性有机化合物和/或多环芳烃。 这些方法既可降低与纳米结构形成相关的成本，又能减少纳米结构制造对环境和公共卫生与安全的有害影响。
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5.发明授权
公开(公告)号：US5614494A
公开(公告)日：1997-03-25
申请号：US303025
申请日：1994-09-08
IPC分类号： A61K38/00 , C07K7/08 , C07K14/00 , C07K14/46 , C07K14/745
CPC分类号： C07K7/08 , C07K14/001 , C07K14/46 , A61K38/00
摘要： Less toxic agents for reversal of heparin or low molecular weight heparin anticoagulation which are synthetic protamine-like polycationic peptides having a total cationic charge which is less than that of n-protamine. In preferred embodiments, arginine residues of n-protamine are replaced with lysine residues for ease of manufacture. Selective positively charged arginine residues have been replaced with an uncharged amino acid residue or its analog, such as glycine or glutamine, in order to reduce the total cationic charge on the polycationic peptide to the range of about [+14] to [+18], preferably [+16] to [+18]. In specific embodiments, there are sequences of 29 and 32 amino acid residues wherein 4 to 5 clusters of 2 to 4 positively charged amino acids are separated by 2 to 6 neutral amino acids. The C-terminus and the N-terminus can be modified to mitigate against in vivo degradation by carboxypeptidases and aminopeptidases. Another modification, specifically use of .alpha.-helix forming amino acids, such as glutamic acid, further promotes anticoagulation reversal.
摘要翻译： 用于逆转肝素或低分子量肝素抗凝剂的毒性较小的药物是具有小于正精蛋白的总阳离子电荷的合成鱼精蛋白样聚阳离子肽。 在优选的实施方案中，为了易于制造，将n-鱼精蛋白的精氨酸残基替换为赖氨酸残基。 选择性带正电的精氨酸残基已被不带电荷的氨基酸残基或其类似物（如甘氨酸或谷氨酰胺）替代，以便将聚阳离子肽上的总阳离子电荷降低至约[+ 14]至[+ 18] ，优选[+ 16]至[+ 18]。 在具体实施方案中，存在29和32个氨基酸残基的序列，其中2至4个带正电荷的氨基酸的4至5个簇被2至6个中性氨基酸分开。 可以修饰C-末端和N-末端以减轻羧肽酶和氨基肽酶的体内降解。 另一个修改，特别是使用α-螺旋形成氨基酸，如谷氨酸，进一步促进抗凝反转。
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公开(公告)号：US5374884A
公开(公告)日：1994-12-20
申请号：US977495
申请日：1992-11-18
申请人： Yoram Koren , Chih-Ching Lo
发明人： Yoram Koren , Chih-Ching Lo
IPC分类号： G05B19/19 , G05D23/275
CPC分类号： G05B19/19 , G05B2219/41154 , G05B2219/42155
摘要： A system for compensating for the effects of friction and other forces reting from repeatable disturbances in a servo system or a numerically controlled machine employs a software-based mathematical model which has certain parameters associated therewith. The parameters are calibrated for the specific characteristics of the system using either off-line or on-line methods, and include dynamic correction for continuous correction, as would be required to compensate for forces which disturb a desired motion. The compensation model is implemented in two stages: (i) building a calibrated mathematical model that describes a repeatable disturbance force, such as friction, and (ii) using the model in real time to compensate for the disturbance force. The model provides a compensation signal which is combined with the original controller signal to yield a compensated control signal. The compensation may be in the form of a position offset. This compensation system is general in its application and can compensate for any deterministic repeatable action that disturbs or acts against the motion of a numerically controlled, or servo, system.
摘要翻译： 用于补偿由伺服系统或数控机器中的可重复干扰产生的摩擦和其他力的影响的系统采用具有与其相关联的某些参数的基于软件的数学模型。 使用离线或在线方法对系统的特定特性进行参数校准，并包括用于连续校正的动态校正，这将需要补偿干扰所需运动的力。 补偿模型分两个阶段实施：（i）建立一个描述可重复干扰力（如摩擦）的校准数学模型，以及（ii）实时使用该模型来补偿扰动力。 该模型提供了与原始控制器信号组合的补偿信号，以产生补偿控制信号。 补偿可以是位置偏移的形式。 该补偿系统在其应用中是通用的，并且可以补偿干扰或作用于数字控制或伺服系统的运动的任何确定性重复动作。
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