公开(公告)号：US06949601B1

公开(公告)日：2005-09-27

申请号：US10070915

申请日：2000-09-11

申请人： Kari-Anne Leth-Olsen ,  Øystein Paulsen ,  Steinar Pedersen ,  Bård Sæthre ,  Rolf Olaf Larsen

发明人： Kari-Anne Leth-Olsen ,  Øystein Paulsen ,  Steinar Pedersen ,  Bård Sæthre ,  Rolf Olaf Larsen

IPC分类号： A61K8/72 ,  B01J20/281 ,  B01J20/30 ,  C08F2/08 ,  C08F2/44 ,  C08F257/02 ,  C08F265/04 ,  C08F271/02 ,  C08F291/00 ,  C08F2/16

CPC分类号： C08F257/02 ,  C08F265/04 ,  C08F271/02 ,  C08F291/00 ,  Y10S526/909

摘要： The present invention concerns large spherical polymer particles with a narrow size distribution and a procedure for producing such particles. The procedure is characterized in that a seed polymerization is performed in which the start particles have a very high ability to absorb new monomer so that finished particles are obtained after only one stage of polymerization even if the finished particles are to be as large as in the range 10 to 100 μm. The procedure is also characterized in that, when porous particles are produced, a porous structure can be formed in which the fraction of micropores is insignificant. Another characteristic feature of the procedure is that the size distribution of the finished particles is narrow and in some cases narrower than in the start particles.

摘要翻译： 本发明涉及具有窄尺寸分布的大球形聚合物颗粒和用于生产这种颗粒的方法。 该方法的特征在于，进行种子聚合，其中起始颗粒具有非常高的吸收新单体的能力，使得仅在一个聚合阶段获得成品颗粒，即使成品颗粒与在 范围10至100 mum。 该方法的特征还在于，当制造多孔颗粒时，可以形成多孔结构，其中微孔的分数不显着。 该方法的另一个特征是成品颗粒的尺寸分布窄，在某些情况下比起始颗粒更窄。