公开(公告)号：US06954662B2

公开(公告)日：2005-10-11

申请号：US10643804

申请日：2003-08-19

Applicant: David Freger ,  Avner Gal ,  Alexander M. Raykhman

Inventor： David Freger ,  Avner Gal ,  Alexander M. Raykhman

IPC: A61B5/00 ,  G06F20060101

CPC classification number: A61B5/417 ,  A61B5/01 ,  A61B5/053 ,  A61B5/14532 ,  A61B7/00

Abstract: The method of monitoring or measuring the concentration of glucose level in human and animal blood uses a non-invasive technique and includes measurements of the speed of sound through the blood, the conductivity of the blood, and the heat capacity of the blood, or by non-invasive measurement of any other parameters that can be used to calculate the glucose level. Thereafter, the glucose level for each of the three measurements is calculated and the final glucose value is determined by a weighted average of the three calculated glucose values.

Abstract translation: 监测或测量人体和动物血液中葡萄糖浓度的方法采用非侵入性技术，包括通过血液的声速，血液的电导率和血液热容量的测量，或由 可以用于计算葡萄糖水平的任何其他参数的非侵入式测量。 此后，计算三个测量中的每一个的葡萄糖水平，并且通过三个计算的葡萄糖值的加权平均值来确定最终葡萄糖值。

公开(公告)号：US20120271133A1

公开(公告)日：2012-10-25

申请号：US13540656

申请日：2012-07-03

Applicant: Avner Gal ,  Alexander M. Raykhman ,  Eugene Naidis ,  Yulia Mayzel ,  Alexander Klionsky ,  Anatoly Diber

Inventor： Avner Gal ,  Alexander M. Raykhman ,  Eugene Naidis ,  Yulia Mayzel ,  Alexander Klionsky ,  Anatoly Diber

IPC: A61B5/1491 ,  A61B5/053 ,  A61B5/01 ,  A61B5/145

CPC classification number: A61B5/14532 ,  A61B5/6816

Abstract: In order to increase the accuracy of non-invasive glucose measurement, the device uses a combination of three non-invasive methods: ultrasonic, electromagnetic and thermal. The non-invasive glucose monitor comprises a Main Unit, which drives three different sensor channels (one per technology), located on an external unit configured as an ear clip attached to the subject's ear lobe. To effect the ultrasonic channel, ultrasonic piezo elements are positioned on opposing portions of the ear clip and thus opposite sides of the ear lobe. For implementation of the electromagnetic channel, capacitor plates are positioned on opposing portions of the ear clip and the ear lobe serves as the dielectric. The thermal channel includes a heater and a sensor positioned on the ear clip in close juxtaposition to the ear lobe.

Abstract translation: 为了提高非侵入性葡萄糖测量的准确性，该装置采用三种非侵入性方法的组合：超声波，电磁和热能。 非侵入式葡萄糖监测器包括主单元，其驱动三个不同的传感器通道（每个技术一个），位于配置为附接到被检者耳垂的耳夹的外部单元上。 为了实现超声波通道，超声波压电元件位于耳夹的相对部分上，并且因此位于耳垂的相对侧。 为了实现电磁通道，电容器板位于耳夹的相对部分上，耳垂片用作电介质。 热通道包括加热器和位于耳夹上的传感器，与耳垂并排放置。

公开(公告)号：US20050043602A1

公开(公告)日：2005-02-24

申请号：US10643804

申请日：2003-08-19

Applicant: David Freger ,  Avner Gal ,  Alexander Raykhman

Inventor： David Freger ,  Avner Gal ,  Alexander Raykhman

IPC: A61B5/00 ,  G06F20060101

CPC classification number: A61B5/417 ,  A61B5/01 ,  A61B5/053 ,  A61B5/14532 ,  A61B7/00

Abstract: The method of monitoring or measuring the concentration of glucose level in human and animal blood uses a non-invasive technique and includes measurements of the speed of sound through the blood, the conductivity of the blood, and the heat capacity of the blood, or by non-invasive measurement of any other parameters that can be used to calculate the glucose level. Thereafter, the glucose level for each of the three measurements is calculated and the final glucose value is determined by a weighted average of the three calculated glucose values.

公开(公告)号：US20110263956A1

公开(公告)日：2011-10-27

申请号：US13090535

申请日：2011-04-20

Applicant: AVNER GAL ,  Alexander M. Raykhman ,  Eugene Naidis ,  Yulia Mayzel ,  Alexander Klionsky ,  Anatoly Diber

Inventor： AVNER GAL ,  Alexander M. Raykhman ,  Eugene Naidis ,  Yulia Mayzel ,  Alexander Klionsky ,  Anatoly Diber

IPC: A61B5/145

CPC classification number: A61B5/14532 ,  A61B5/6816

Abstract: In order to increase the accuracy of non-invasive glucose measurement, the device uses a combination of three non-invasive methods: ultrasonic, electromagnetic and thermal. The non-invasive glucose monitor comprises a Main Unit, which drives three different sensor channels (one per technology), located on an external unit configured as an ear clip attached to the subject's ear lobe. To effect the ultrasonic channel, ultrasonic piezo elements are positioned on opposing portions of the ear clip and thus opposite sides of the ear lobe. For implementation of the electromagnetic channel, capacitor plates are positioned on opposing portions of the ear clip and the ear lobe serves as the dielectric. The thermal channel includes a heater and a sensor positioned on the ear clip in close juxtaposition to the ear lobe.

Abstract translation: 为了提高非侵入性葡萄糖测量的准确性，该装置采用三种非侵入性方法的组合：超声波，电磁和热能。 非侵入式葡萄糖监测器包括主单元，其驱动三个不同的传感器通道（每个技术一个），位于配置为附接到被检者耳垂的耳夹的外部单元上。 为了实现超声波通道，超声波压电元件位于耳夹的相对部分上，并且因此位于耳垂的相对侧。 为了实现电磁通道，电容器板位于耳夹的相对部分上，耳垂片用作电介质。 热通道包括加热器和位于耳夹上的传感器，与耳垂并排放置。

公开(公告)号：US08235897B2

公开(公告)日：2012-08-07

申请号：US13090535

申请日：2011-04-20

Applicant: Avner Gal ,  Alexander M. Raykhman ,  Eugene Naidis ,  Yulia Mayzel ,  Alexander Klionsky ,  Anatoly Diber

Inventor： Avner Gal ,  Alexander M. Raykhman ,  Eugene Naidis ,  Yulia Mayzel ,  Alexander Klionsky ,  Anatoly Diber

IPC: A61B5/00

CPC classification number: A61B5/14532 ,  A61B5/6816

Abstract: In order to increase the accuracy of non-invasive glucose measurement, the device uses a combination of three non-invasive methods: ultrasonic, electromagnetic and thermal. The non-invasive glucose monitor comprises a Main Unit, which drives three different sensor channels (one per technology), located on an external unit configured as an ear clip attached to the subject's ear lobe. To effect the ultrasonic channel, ultrasonic piezo elements are positioned on opposing portions of the ear clip and thus opposite sides of the ear lobe. For implementation of the electromagnetic channel, capacitor plates are positioned on opposing portions of the ear clip and the ear lobe serves as the dielectric. The thermal channel includes a heater and a sensor positioned on the ear clip in close juxtaposition to the ear lobe.

Abstract translation: 为了提高非侵入性葡萄糖测量的准确性，该装置采用三种非侵入性方法的组合：超声波，电磁和热能。 非侵入式葡萄糖监测器包括主单元，其驱动三个不同的传感器通道（每个技术一个），位于配置为附接到被检者耳垂的耳夹的外部单元上。 为了实现超声波通道，超声波压电元件位于耳夹的相对部分上，并且因此位于耳垂的相对侧。 为了实现电磁通道，电容器板位于耳夹的相对部分上，耳垂片用作电介质。 热通道包括加热器和位于耳夹上的传感器，与耳垂并排放置。