公开(公告)号：US20080200733A1

公开(公告)日：2008-08-21

申请号：US11994781

申请日：2006-06-21

Applicant: Abhay Upare ,  Ganesh Wagh ,  Amit Chavan ,  Wazid Sajjad Jafri ,  Sabapathi Selvakumar ,  Mita Roy

Inventor： Abhay Upare ,  Ganesh Wagh ,  Amit Chavan ,  Wazid Sajjad Jafri ,  Sabapathi Selvakumar ,  Mita Roy

IPC: C07C45/85 ,  C07C45/00 ,  C07C33/42

CPC classification number: C07J21/00 ,  C07C17/16 ,  C07C17/383 ,  C07C17/392 ,  C07C29/78 ,  C07C45/676 ,  C07C67/343 ,  C07C21/14 ,  C07C49/203 ,  C07C69/738 ,  C07C33/02

Abstract: The present invention relates to processes for the preparation of purified solanesol, solanesyl bromide & solanesyl acetone. Solanesyl acetone has the chemical name—all—trans 6,10,14,18,22,26,30,34,38-nonamethyl-5,9,13,17,21,25,29,33,37-triacontanonaen-2-one, of formula 1 and is used for synthesis of coenzyme Q10.

Abstract translation: 本发明涉及制备纯化的茄anes醇，茄yl基sol啶基丙酮的方法。 苯磺酰丙酮具有化学名称全反式6,10,14,18,22,26,30,34,38-非甲基-5,9,13,17,21,25,29,33,37-三十碳烯酸 - 2-酮，其用于合成辅酶Q 10。

公开(公告)号：US20050070586A1

公开(公告)日：2005-03-31

申请号：US10913121

申请日：2004-08-05

Applicant: Ashok Kumar ,  Rajesh Kumar Keshava Prasad Singh ,  Nalinakshya Panda ,  Abhay Upare ,  Manmohan Nimbalkar ,  Satish Soudagar ,  Ashvini Kumar Nand Kishore Saxena

Inventor： Ashok Kumar ,  Rajesh Kumar Keshava Prasad Singh ,  Nalinakshya Panda ,  Abhay Upare ,  Manmohan Nimbalkar ,  Satish Soudagar ,  Ashvini Kumar Nand Kishore Saxena

IPC: A61K31/4184 ,  C07D403/10 ,  C07D43/02

CPC classification number: A61K31/4184 ,  C07D403/10

Abstract: Improved processes using primary, secondary and tertiary alcohols and with safer mode of introduction of the reagent and reaction conditions are described. Further, the process of manufacture of Losartan potassium by use of alkali metal salt such as Potassium carbonate is disclosed. A process for preparation of the polymorphic Form I of Losartan potassium is also disclosed herein.

Abstract translation: 描述了使用伯醇，仲醇和叔醇以及更安全的引入试剂和反应条件的改进方法。 此外，公开了通过使用碱金属盐如碳酸钾制造氯沙坦钾的方法。 本文还公开了制备氯沙坦钾的多晶型I的方法。

公开(公告)号：US20080200732A1

公开(公告)日：2008-08-21

申请号：US11994797

申请日：2006-06-21

Applicant: Abhay Upare ,  Nitin Yeshwant Pawar ,  Ganesh Wagh ,  Amit Chavan ,  Mita Roy ,  Hariharan Sivaramakrishnan

Inventor： Abhay Upare ,  Nitin Yeshwant Pawar ,  Ganesh Wagh ,  Amit Chavan ,  Mita Roy ,  Hariharan Sivaramakrishnan

IPC: C07C45/61 ,  C07C43/215 ,  C07C41/30 ,  C07C43/225

CPC classification number: C07F3/02 ,  C07C41/22 ,  C07C41/26 ,  C07C41/30 ,  C07C41/48 ,  C07C41/52 ,  C07C43/215 ,  C07C46/08 ,  C07C50/28 ,  C07C43/23 ,  C07C43/315

Abstract: The present invention relates to novel intermediates for the preparation of coenzymes, processes for the preparation of the intermediates and an improved process for the preparation of Coenzymes. The present invention particularly relates to an improved process for the preparation of Coenzyme Q, more particularly for Conenzyme Q9 and Coenzyme Q10. Still more particularly this invention relates to regio and stereo controlled process for the preparation of Coenzyme Q9 and Coenzyme Q10 of the formula I where n=9 (Coenzyme CoQ9), and where n=10. (Coenzyme CoQ10)

Abstract translation: 本发明涉及用于制备辅酶的新型中间体，制备中间体的方法和用于制备辅酶的改进方法。 本发明特别涉及一种用于制备辅酶Q的改进方法，更特别地涉及用于连接酶Q 9和辅酶Q 10的辅酶Q的改进方法。 更具体地说，本发明涉及用于制备式I的辅酶Q 9和辅酶Q 10的区域和立体控制方法，其中n = 9（辅酶CoQ _{9 ），其中n = 10。 （辅酶QQ 10）}

公开(公告)号：US06916935B2

公开(公告)日：2005-07-12

申请号：US10431847

申请日：2003-05-07

Applicant: Ashok Kumar ,  Rajeshkumar Singh ,  Nalinakshya Panda ,  Abhay Upare ,  Manmohan Nimbalkar ,  Satish Soudagar

Inventor： Ashok Kumar ,  Rajeshkumar Singh ,  Nalinakshya Panda ,  Abhay Upare ,  Manmohan Nimbalkar ,  Satish Soudagar

IPC: A61K31/4184 ,  C07D403/10 ,  C07D257/00

CPC classification number: C07D403/10 ,  A61K31/4184

Abstract: A process for the synthesis of Losartan Potassium by reacting Trityl Losartan in a primary alcohol with potassium tertiary alkoxide.

Abstract translation: 通过使三苯甲基氯沙坦与伯醇与叔醇钾反应合成氯沙坦钾的方法。