Method for prediction of sensitivity to 5-fluorouracil-type anticancer agent
    1.
    发明授权
    Method for prediction of sensitivity to 5-fluorouracil-type anticancer agent 失效
    5-氟尿嘧啶型抗癌剂敏感性预测方法

    公开(公告)号:US08440398B2

    公开(公告)日:2013-05-14

    申请号:US12161957

    申请日:2007-01-23

    IPC分类号: C12Q1/68

    摘要: A factor affecting sensitivities to anticancer agents is analyzed and the validity of the factor is demonstrated.The present invention provides a method for predicting sensitivities to 5-fluorouracil-based anticancer agents using the copy number of dihydropyrimidine dehydrogenase gene as an indicator. Also disclosed are a kit and primers for use in predicting sensitivities to 5-fluorouracil-based anticancer agents.

    摘要翻译: 分析影响对抗癌剂敏感性的因素,并证明该因子的有效性。 本发明提供了使用二氢嘧啶脱氢酶基因拷贝数作为指标来预测对5-氟尿嘧啶类抗癌剂敏感性的方法。 还公开了用于预测对5-氟尿嘧啶基抗癌剂敏感性的试剂盒和引物。

    METHOD FOR PREDICTION OF SENSITIVITY TO 5-FLUOROURACIL-TYPE ANTICANCER AGENT
    2.
    发明申请
    METHOD FOR PREDICTION OF SENSITIVITY TO 5-FLUOROURACIL-TYPE ANTICANCER AGENT 失效
    用于预测5-氟尿嘧啶型抗原剂敏感性的方法

    公开(公告)号:US20090197264A1

    公开(公告)日:2009-08-06

    申请号:US12161957

    申请日:2007-01-23

    IPC分类号: C12Q1/68 C07H21/00

    摘要: A factor affecting sensitivities to anticancer agents is analyzed and the validity of the factor is demonstrated.The present invention provides a method for predicting sensitivities to 5-fluorouracil-based anticancer agents using the copy number of dihydropyrimidine dehydrogenase gene as an indicator. Also disclosed are a kit and primers for use in predicting sensitivities to 5-fluorouracil-based anticancer agents.

    摘要翻译: 分析影响对抗癌剂敏感性的因素,并证明该因子的有效性。 本发明提供了使用二氢嘧啶脱氢酶基因拷贝数作为指标来预测对5-氟尿嘧啶类抗癌剂敏感性的方法。 还公开了用于预测对5-氟尿嘧啶基抗癌剂敏感性的试剂盒和引物。