公开(公告)号：US11622982B2

公开(公告)日：2023-04-11

申请号：US16638546

申请日：2018-08-17

申请人： Akrivista, LLC

发明人： Scott Whitcup ,  Orest Olejnik ,  Michael Garst ,  Peter Simmons

IPC分类号： A61P27/04 ,  A61K9/00 ,  A61K36/47 ,  A61K36/54 ,  A61K47/44 ,  A61K36/235 ,  A61K9/107 ,  A61K36/534 ,  A61K36/61 ,  A61K36/752 ,  A61K47/32 ,  G01N33/50

摘要： In preferred embodiments the invention is directed to ocular compositions for the treatment of dry eye, methods for making such compositions, and suites comprising a plurality of different ocular compositions each having a defined composition. In preferred examples, the invention is directed to compositions comprising at least one natural oil, wherein a first member of the suite of compositions is effective in treating dry in in a first patient having a particular set of symptoms and a different second member of the suite of compositions is effective in treating dry in in a second patient having a different set of symptoms. The invention is also directed to methods of making and using the compositions, and to skin care compositions for use around the eye, such as the upper and lower eyelids having a lubricating, non-irritating base composition comprising at least one natural oil.

公开(公告)号：US20200164013A1

公开(公告)日：2020-05-28

申请号：US16638546

申请日：2018-08-17

申请人： Akrivista, LLC

发明人： Scott Whitcup ,  Orest Olejnik ,  Michael Garst ,  Peter Simmons

IPC分类号： A61K36/235 ,  A61K36/47 ,  A61K36/534 ,  A61K36/54 ,  A61K36/61 ,  A61K36/752 ,  A61K47/32 ,  A61K47/44 ,  A61K9/00 ,  A61K9/107 ,  A61P27/04 ,  G01N33/50

摘要： In preferred embodiments the invention is directed to ocular compositions for the treatment of dry eye, methods for making such compositions, and suites comprising a plurality of different ocular compositions each having a defined composition. In preferred examples, the invention is directed to compositions comprising at least one natural oil, wherein a first member of the suite of compositions is effective in treating dry in in a first patient having a particular set of symptoms and a different second member of the suite of compositions is effective in treating dry in in a second patient having a different set of symptoms. The invention is also directed to methods of making and using the compositions, and to skin care compositions for use around the eye, such as the upper and lower eyelids having a lubricating, non-irritating base composition comprising at least one natural oil.

公开(公告)号：US11903986B2

公开(公告)日：2024-02-20

申请号：US15680998

申请日：2017-08-18

申请人： Akrivista LLC

发明人： Scott Whitcup ,  Orest Olejnik ,  Michael Garst

IPC分类号： A61K9/00 ,  A61K36/185 ,  A61K36/61 ,  A61K31/7048 ,  A61K9/08 ,  A61K9/107 ,  A61K36/534 ,  A61K36/752 ,  A61K36/235 ,  A61K31/045 ,  A61K33/14 ,  A61K47/26 ,  A61K47/10 ,  A61K47/32 ,  A61K47/38 ,  A61K33/00 ,  A61K33/20 ,  A61K33/22 ,  A61K47/18 ,  G01N33/487 ,  G01N33/84 ,  G01N33/68 ,  A61K36/54 ,  A61K45/06

CPC分类号： A61K36/185 ,  A61K9/0048 ,  A61K9/08 ,  A61K9/107 ,  A61K9/1075 ,  A61K31/045 ,  A61K31/7048 ,  A61K33/00 ,  A61K33/14 ,  A61K33/20 ,  A61K33/22 ,  A61K36/235 ,  A61K36/534 ,  A61K36/54 ,  A61K36/61 ,  A61K36/752 ,  A61K45/06 ,  A61K47/10 ,  A61K47/183 ,  A61K47/26 ,  A61K47/32 ,  A61K47/38 ,  G01N33/487 ,  G01N33/6827 ,  G01N33/6893 ,  G01N33/84 ,  G01N2800/16

摘要： In preferred the invention is directed to ocular compositions for the treatment of dry eye, methods for making such compositions, and suites comprising a plurality of different ocular compositions each having a defined composition. In preferred examples, the invention is directed to compositions comprising at least one natural oil, wherein a first member of the suite of compositions is effective in treating dry in in a first patient having a particular set of symptoms and a different second member of the suite of compositions is effective in treating dry in in a second patient having a different set of symptoms. The invention is also directed to methods of making and using the compositions, and to skin care compositions for use around the eye, such as the upper and lower eyelids having a lubricating, non-irritating base composition comprising at least one natural oil.

公开(公告)号：US20230233637A1

公开(公告)日：2023-07-27

申请号：US18129182

申请日：2023-03-31

申请人： Akrivista LLC

发明人： Scott Whitcup ,  Orest Olejnik ,  Michael Garst ,  Peter Simmons

IPC分类号： A61K36/235 ,  A61P27/04 ,  A61K9/00 ,  A61K36/534 ,  A61K36/61 ,  G01N33/50 ,  A61K36/54 ,  A61K36/752 ,  A61K47/32 ,  A61K9/107 ,  A61K36/47 ,  A61K47/44

CPC分类号： A61K36/235 ,  A61P27/04 ,  A61K9/0048 ,  A61K36/534 ,  A61K36/61 ,  G01N33/50 ,  A61K36/54 ,  A61K36/752 ,  A61K47/32 ,  A61K9/1075 ,  A61K36/47 ,  A61K47/44

摘要： In preferred embodiments the invention is directed to ocular compositions for the treatment of dry eye, methods for making such compositions, and suites comprising a plurality of different ocular compositions each having a defined composition. In preferred examples, the invention is directed to compositions comprising at least one natural oil, wherein a first member of the suite of compositions is effective in treating dry in in a first patient having a particular set of symptoms and a different second member of the suite of compositions is effective in treating dry in in a second patient having a different set of symptoms. The invention is also directed to methods of making and using the compositions, and to skin care compositions for use around the eye, such as the upper and lower eyelids having a lubricating, non-irritating base composition comprising at least one natural oil.

公开(公告)号：US20180050074A1

公开(公告)日：2018-02-22

申请号：US15680998

申请日：2017-08-18

申请人： Akrivista, LLC

发明人： Scott Whitcup ,  Orest Olejnik ,  Michael Garst

IPC分类号： A61K36/185 ,  A61K36/54 ,  A61K36/61 ,  A61K31/7048 ,  A61K9/08 ,  A61K9/107 ,  A61K36/534 ,  A61K36/752 ,  A61K36/235 ,  A61K31/045 ,  A61K9/00 ,  A61K33/14 ,  A61K47/26 ,  A61K47/10 ,  A61K47/32 ,  A61K47/38 ,  A61K33/00 ,  A61K33/20 ,  A61K33/22 ,  A61K47/18 ,  G01N33/487 ,  G01N33/84 ,  G01N33/68

摘要： In preferred the invention is directed to ocular compositions for the treatment of dry eye, methods for making such compositions, and suites comprising a plurality of different ocular compositions each having a defined composition. In preferred examples, the invention is directed to compositions comprising at least one natural oil, wherein a first member of the suite of compositions is effective in treating dry in in a first patient having a particular set of symptoms and a different second member of the suite of compositions is effective in treating dry in in a second patient having a different set of symptoms. The invention is also directed to methods of making and using the compositions, and to skin care compositions for use around the eye, such as the upper and lower eyelids having a lubricating, non-irritating base composition comprising at least one natural oil.