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公开(公告)号:US20060205824A1
公开(公告)日:2006-09-14
申请号:US11434037
申请日:2006-05-15
IPC分类号: A61K31/105 , C07C321/02
CPC分类号: A61K31/105 , A61K31/10 , C07C323/65
摘要: The invention provides enantiomers of ajoene and derivatives of Z(−)-ajoene. The derivative of Z(−)-ajoene are useful for modulating integrin-mediated functions, for treating disorders, diseases or conditions in which integrins play a role, and for treating tissues to improve their condition for a subsequent use, such as transplantation.
摘要翻译: 本发明提供了ajoene和Z( - ) - ajoene衍生物的对映异构体。 Z( - ) - ajoene的衍生物可用于调节整联蛋白介导的功能,用于治疗整合素起作用的疾病,疾病或病症,以及治疗组织以改善其后续使用如移植的状况。