公开(公告)号：US4399820A

公开(公告)日：1983-08-23

申请号：US346315

申请日：1982-02-05

申请人： Alexander Wirtzfeld ,  Roland Heinze ,  Thomas Bock ,  Hans D. Liess

发明人： Alexander Wirtzfeld ,  Roland Heinze ,  Thomas Bock ,  Hans D. Liess

IPC分类号： A61B5/00 ,  A61B5/145 ,  A61B5/1459 ,  A61N1/365 ,  A61N1/36

CPC分类号： A61N1/36557 ,  A61B5/1459

摘要： A process and a device for regulating the stimulation frequency of heart pacemakers are disclosed. The process comprises generating with the aid of light emitted by a light-emitting element, reflected by the blood of a patient, and received by a light-receiving element, a current flow which causes, in a measuring probe, an increasing of the current flow at a constant probe voltage or a damping of the probe voltage at constant current flow. Thereafter, one of the possible changing values is measured and the change, with time, is evaluated as a measured quantity proportional to the change, with time, of the blood oxygen saturation, and, as a function of the measured quantity, the stimulation frequency of the heart pacemaker is regulated in such a manner that the greatest possible blood oxygen saturation is always achieved with the lowest stimulation frequency. The device for practicing the invention comprises a measuring probe containing at least one combination of only two active optoelectronic elements, one light-emitting element and one light-receiving element; a control circuit electrically connected to the measuring probe; a stimulation catheter in which the measuring probe is incorporated, and at least two electric lines leading through the stimulation catheter and electrically connecting the measuring probe to the control circuit of the measuring probe.

摘要翻译： 公开了一种用于调节心脏起搏器刺激频率的过程和装置。 该过程包括借助由发光元件发射的光产生，由患者的血液反射并由光接收元件接收的电流，其在测量探针中引起电流的增加 在恒定电流下以恒定的探针电压或探针电压的阻尼流动。 此后，测量可能的变化值之一，随时间的变化被评估为与血氧饱和度随时间的变化成比例的测量量，并且作为测量量的函数，刺激频率 心脏起搏器的调节方式是以最低的刺激频率始终实现最大可能的血氧饱和度。 用于实施本发明的装置包括测量探头，其包含仅两个有源光电元件，一个发光元件和一个光接收元件的至少一个组合; 电连接到所述测量探针的控制电路; 其中结合有测量探针的刺激导管和通过刺激导管的至少两条电线，并将测量探针电连接到测量探针的控制电路。

公开(公告)号：US4202339A

公开(公告)日：1980-05-13

申请号：US970894

申请日：1978-12-19

申请人： Alexander Wirtzfeld ,  Thomas Bock

发明人： Alexander Wirtzfeld ,  Thomas Bock

IPC分类号： A61B5/00 ,  A61B5/024 ,  A61N1/365 ,  A61N1/36

CPC分类号： A61B5/02433 ,  A61B5/1459 ,  A61N1/36557

摘要： A cardiac pacemaker includes means for conforming the stimulation frequency to the bodily stressing conditions of the wearer of the pacemaker in using a blood parameter as measuring value for the influencing of the frequency of stimulation. A measuring probe is implanted in the heart of the wearer of the pacemaker for measuring the oxygen saturation of the blood. The measuring value thereby resulting serves as measuring parameter for the influencing of the frequency of stimulation.

摘要翻译： 心脏起搏器包括在使用血液参数作为影响刺激频率的测量值时使刺激频率与起搏器的佩戴者的身体应激条件一致的装置。 将测量探针植入起搏器穿戴者的心脏中，以测量血液的氧饱和度。 由此产生的测量值用作影响刺激频率的测量参数。

公开(公告)号：US4763655A

公开(公告)日：1988-08-16

申请号：US62707

申请日：1987-06-16

申请人： Alexander Wirtzfeld ,  Karl Stangl ,  Roland Heinze

发明人： Alexander Wirtzfeld ,  Karl Stangl ,  Roland Heinze

IPC分类号： A61B5/145 ,  A61B5/00 ,  A61B5/1459 ,  A61B5/15 ,  A61B5/157 ,  A61N1/365 ,  A61N1/36

CPC分类号： A61B5/1459 ,  A61N1/3655 ,  A61N1/36557

摘要： The stimulation frequency of a heart pacemaker is controlled dependent on a signal representative of the blood oxygen content of the patient. The blood oxygen dependent signal is generated by a blood oxygen sensor. A temperature sensor generates a separate signal dependent on blood temperature. The blood oxygen and blood temperature signals are combined such that the blood oxygen signal is lowered, i.e., the value thereof is reduced, in ranges of higher physical load indicated by an increase in the temperature dependent signal. The combined signal is used to control the stimulation frequency of a heart pacemaker so that the stimulation frequency is increased, if blood oxygen saturation is decreasing and/or blood temperature is increasing.

摘要翻译： 心脏起搏器的刺激频率由代表患者血氧含量的信号控制。 血氧依赖信号由血氧传感器产生。 温度传感器根据血液温度生成独立的信号。 组合血氧信号和血液温度信号，使得在依赖于温度的信号的增加指示的较高物理负荷的范围内，血氧信号降低，即其值降低。 组合信号用于控制心脏起搏器的刺激频率，使得如果血氧饱和度降低和/或血液温度升高，则刺激频率增加。

公开(公告)号：US3970076A

公开(公告)日：1976-07-20

申请号：US546907

申请日：1975-02-04

申请人： Wolfgang Hepp ,  Alexander Wirtzfeld

发明人： Wolfgang Hepp ,  Alexander Wirtzfeld

IPC分类号： A61H23/00 ,  A61H31/00 ,  A61N7/00 ,  G10K15/06

CPC分类号： G10K15/06 ,  A61H23/008 ,  A61H31/006 ,  A61N7/00 ,  A61H2201/1238 ,  A61N2007/0026

摘要： A heart stimulator adapted to be used outside the body comprising pressure wave generating means and coupling means adapted to be placed on the surface of the body in the area of the heart without an air gap.

摘要翻译： 适于在身体外部使用的心脏刺激器包括压力波发生装置和适于在心脏区域放置在身体表面上而没有气隙的联接装置。