TRANSDERMAL DRUG DELIVERY COMPOSITIONS AND TOPICAL COMPOSITIONS FOR APPLICATION ON THE SKIN
    2.
    发明申请
    TRANSDERMAL DRUG DELIVERY COMPOSITIONS AND TOPICAL COMPOSITIONS FOR APPLICATION ON THE SKIN 审中-公开
    透皮药物输送组合物和适用于皮肤的局部组合物

    公开(公告)号:US20090053290A1

    公开(公告)日:2009-02-26

    申请号:US12281768

    申请日:2007-03-08

    摘要: Transdermal delivery compositions and topical compositions for application to the skin are provided. The transdermal delivery composition includes at least two penetrants working synergistically but by disparate biochemical pathways. In one embodiment, the transdermal delivery system includes benzyl alcohol and lecithin organogel. The transdermal delivery compositions are used in a variety of topical compositions as a means of transdermally delivering and topically administering different drugs and agents, including compositions promoting collagen biosynthesis, retinoids and skin lighteners, chemical denervation agents such as BOTOX®, anti-fungal agents, anesthetics and non-steroidal anti-inflammatory drugs (NSAIDs). In addition, these topical compositions may be used in combination with non-ablative treatment modalities, such as microdermabrasion, laser-based skin remodeling and radio-frequency-based skin remodeling.

    摘要翻译: 提供用于皮肤的透皮递送组合物和局部组合物。 透皮递送组合物包括至少两种渗透剂,其协同作用,但通过不同的生化途径。 在一个实施方案中,透皮递送系统包括苄醇和卵磷脂有机凝胶。 透皮递送组合物用于多种局部组合物中,作为经皮递送和局部施用不同药物和试剂的手段,包括促进胶原生物合成的组合物,类视色素和皮肤增亮剂,化学去神经调节剂如BOTOX,抗真菌剂 药物,麻醉剂和非甾体抗炎药(NSAIDs)。 此外,这些局部组合物可以与非消融治疗方式组合使用,例如微磨皮,基于激光的皮肤重塑和基于射频的皮肤重塑。