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公开(公告)号:US20090232899A1
公开(公告)日:2009-09-17
申请号:US11596934
申请日:2005-05-20
IPC分类号: A61K9/50 , A61K38/43 , A61K38/00 , A61K31/165 , A61K31/43
CPC分类号: A61K9/143 , A61K9/146 , A61K9/5115 , A61K9/5161 , A61K9/5192
摘要: A nanocomposite delivery system uses chitosan as a mucoadhesive material encapsulated in a surface modified network of colloidal nanoporous nanoparticles, such as silica, or other colloid-forming materials, especially metal oxides. Drug delivery systems may be provided by binding a drug to the chitosan/silica nanocomposite, typically by adding a drug or other active agent during in-situ gellation of colloidal silica. When the active agent is, for example, amoxicillin or other antibiotic agent, the drug delivery system may be used in the treatment of stomach ulcers, for example.
摘要翻译: 纳米复合物递送系统使用壳聚糖作为胶体纳米多孔纳米颗粒(如二氧化硅)或其他形成胶体的材料,特别是金属氧化物的表面改性网络中的粘膜粘附材料。 药物递送系统可以通过将药物与壳聚糖/二氧化硅纳米复合物结合来提供,通常通过在胶体二氧化硅的原位凝胶化过程中加入药物或其它活性剂。 当活性剂是例如阿莫西林或其它抗生素时,药物递送系统可用于例如胃溃疡的治疗。
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公开(公告)号:US20110054236A1
公开(公告)日:2011-03-03
申请号:US12857986
申请日:2010-08-17
申请人: Victor C. Yang , Beata Chertok , Allan E. David
发明人: Victor C. Yang , Beata Chertok , Allan E. David
CPC分类号: A61K41/00 , A61K9/0009 , A61K9/0085 , A61K9/5094 , A61K9/5115 , A61K47/34 , A61K47/36 , A61K47/6923 , A61N2/002
摘要: The present invention relates to functionalized magnetic nanoparticles. In particular, the present invention provides functionalized magnetic nanoparticles for research and clinical (e.g., targeted treatment) applications.
摘要翻译: 本发明涉及功能化磁性纳米粒子。 特别地,本发明提供用于研究和临床(例如,靶向治疗)应用的官能化磁性纳米颗粒。
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