公开(公告)号：US20240358836A1

公开(公告)日：2024-10-31

申请号：US18519442

申请日：2023-11-27

Applicant: Pulse Therapeutics, Inc.

Inventor： Francis M. Creighton

IPC: A61K41/00 ,  A61B17/00 ,  A61B17/22 ,  A61B34/00 ,  A61K9/00 ,  A61K38/48 ,  A61K47/69 ,  A61N2/00 ,  A61N2/02 ,  A61N2/06 ,  B82Y5/00 ,  H01F7/02

CPC classification number: A61K41/00 ,  A61B17/22 ,  A61B17/22012 ,  A61B34/73 ,  A61K9/0019 ,  A61K38/482 ,  A61K38/484 ,  A61K47/6941 ,  A61N2/004 ,  A61N2/02 ,  A61N2/06 ,  C12Y304/21007 ,  C12Y304/21068 ,  H01F7/0273 ,  A61B2017/00876 ,  A61B2017/22084 ,  A61B2017/22094 ,  A61B2034/733 ,  B82Y5/00 ,  Y10S977/811 ,  Y10S977/905 ,  Y10S977/909

Abstract: A system for the physical manipulation of free magnetic rotors in a circulatory system using a remotely placed magnetic field-generating stator is provided. In one embodiment, the invention relates to the control of magnetic particles in a fluid medium using permanent magnet-based or electromagnetic field-generating stator sources. Such a system can be useful for increasing the diffusion of therapeutic agents in a fluid medium, such as a human circulatory system, which can result in substantial clearance of fluid obstructions, such as vascular occlusions, in a circulatory system resulting in increased blood flow. Examples of vascular occlusions targeted by the system include, but are not limited to, atherosclerotic plaques, including fibrous caps, fatty buildup, coronary occlusions, arterial stenosis, restenosis, vein thrombi, arterial thrombi, cerebral thrombi, embolisms, hemorrhages, other blood clots, and very small vessels.

公开(公告)号：US12036419B2

公开(公告)日：2024-07-16

申请号：US18219366

申请日：2023-07-07

Applicant: Science Corporation

Inventor： Max Hodak ,  Alan Mardinly ,  Yifan Kong

IPC: G09G3/32 ,  A61F2/14 ,  A61K35/30 ,  A61K41/00 ,  A61N5/06

CPC classification number: A61N5/0622 ,  A61F2/14 ,  A61K35/30 ,  A61K41/00 ,  A61N5/062 ,  G09G3/32 ,  A61N2005/0626 ,  A61N2005/0652 ,  G09G2320/0626

Abstract: In variants, a neural interface system (e.g., retinal implant, neural implant, etc.) can include: a display, a controller, a power source, and/or any other suitable components. The system can be used with an external device including a communication element, a display-brain interface (e.g., cells), and/or any other suitable components.

公开(公告)号：US11951325B2

公开(公告)日：2024-04-09

申请号：US16550433

申请日：2019-08-26

Applicant: SHANDONG ZHUSHI PHARMACEUTICAL GROUP CO., LTD.

Inventor： Kunfu Zhu ,  Lei Zhu

IPC: A61N5/06 ,  A61K9/70 ,  A61K36/282 ,  A61K36/286 ,  A61K36/48 ,  A61K36/65 ,  A61K41/00 ,  A61M35/00 ,  A61M37/00 ,  B01J19/12 ,  A61N5/00 ,  B30B11/00 ,  B30B11/34 ,  B65G9/00

CPC classification number: A61N5/0616 ,  A61K9/703 ,  A61K36/282 ,  A61K36/286 ,  A61K36/48 ,  A61K36/65 ,  A61K41/00 ,  A61M35/00 ,  A61M37/00 ,  B01J19/123 ,  A61M2037/0007 ,  A61N5/00 ,  A61N2005/002 ,  A61N5/06 ,  B30B11/00 ,  B30B11/34 ,  B65G9/00

Abstract: A photon cold gel includes a cold gel body, wherein a non-woven fabric is arranged at the top of the cold gel body. A plurality of medicine storing cavities is formed under the cold gel body. Medicine bags are separately and fixedly arranged in each of the medicine storing cavities. Each of the medicine bags includes a ventilated cotton cloth, wherein medicines are loaded in the ventilated cotton cloth, a drainage tube which penetrates upwards through the cold gel body and is flush with the top of the non-woven fabric, is fixedly connected to the upper part of each of the medicine bags. Finally, a sealing plug is arranged at the top of each drainage tube. The present photon cold gel is able to form a micro magnetic field via the randomly distributed magnetic powder to treat human body by magnetic therapy while maintaining its primary function.

公开(公告)号：US11905510B2

公开(公告)日：2024-02-20

申请号：US17146849

申请日：2021-01-12

Applicant: Todd Frank Ovokaitys ,  John Scott Strachan

Inventor： Todd Frank Ovokaitys ,  John Scott Strachan

IPC: C12N13/00 ,  A61K35/28 ,  A61K35/51 ,  A61K41/00 ,  A61N5/06 ,  A61N5/067

CPC classification number: C12N13/00 ,  A61K35/28 ,  A61K35/51 ,  A61K41/00 ,  A61K41/0023 ,  A61N5/062 ,  A61N5/0622 ,  A61N5/067 ,  A61N2005/0626 ,  A61N2005/0659 ,  A61N2005/0662

Abstract: Harvested stem cells are activated by treating them with an amplitude modulated laser beam having a wavelength lying in the range of 405 to 980 nanometers. The frequency of the laser beam is modulated within a range of 8 to 12 MHz. Using the activated stem cells, tissue can be repaired and regenerated by preparing the unactivated stem cells, treating the unactivated stem cells with an amplitude modulated laser beam having a pre-determined frequency for obtaining activated stem cells, administering the activated stem cells into a body containing the tissue, and using a homing beam to guide the activated stem cells within the body to the location of the tissue.

公开(公告)号：US11856849B2

公开(公告)日：2023-12-26

申请号：US16543685

申请日：2019-08-19

Applicant: Merck Patent GmbH

Inventor： Amir Hossain Parham ,  Irina Martynova ,  Anja Jatsch ,  Thomas Eberle ,  Jonas Kroeber ,  Christof Pflumm

IPC: H01L51/54 ,  H10K85/60 ,  C07D405/14 ,  C07D403/10 ,  C07D403/14 ,  C07D409/14 ,  C07D491/048 ,  C07D403/08 ,  C07F7/08 ,  C07F5/02 ,  C07F15/00 ,  A61K41/00 ,  A61N5/06 ,  C07D495/14 ,  C09K11/02 ,  H10K50/11 ,  H10K85/30 ,  H10K101/10 ,  H10K101/00

CPC classification number: H10K85/6572 ,  A61K41/00 ,  A61N5/0616 ,  A61N5/0621 ,  C07D403/08 ,  C07D403/10 ,  C07D403/14 ,  C07D405/14 ,  C07D409/14 ,  C07D491/048 ,  C07D495/14 ,  C07F5/025 ,  C07F7/0814 ,  C07F15/0033 ,  C07F15/0086 ,  C09K11/025 ,  H10K85/654 ,  H10K85/657 ,  H10K85/6574 ,  H10K85/6576 ,  A61N2005/0653 ,  H10K50/11 ,  H10K85/342 ,  H10K85/631 ,  H10K2101/10 ,  H10K2101/90 ,  Y02E10/549

Abstract: Compounds of formula (1) that have functional substituents in a specific spatial arrangement, and electronic devices that include a compound of formula (1), and to the preparation of compounds of formula (1).

公开(公告)号：US20230380922A1

公开(公告)日：2023-11-30

申请号：US18248963

申请日：2021-10-15

Applicant: SIGMA-7 E.U.

Inventor： Norbert Frischauf ,  Alexander Kraus ,  Robert Mayer

IPC: A61B34/00 ,  H01F7/20 ,  A61N2/02 ,  A61N2/00 ,  A61K41/00

CPC classification number: A61B34/73 ,  H01F7/202 ,  A61N2/02 ,  A61N2/004 ,  A61K41/00 ,  A61B2034/733

Abstract: A device for environmentally friendly destruction of health-relevant and cosmetically/aesthetically relevant cell structures, in particular tumour cells, which have at least one metallic nanoparticle on their cell membrane, is disclosed. The device includes a primary coil for generating an inhomogeneous primary magnetic field, a secondary coil for generating an inhomogeneous secondary magnetic field and a control device which is designed for actuating the primary coil in such a way that the nanoparticle is deflected by the primary magnetic field and for actuating the secondary coil in such a way that the secondary magnetic field oscillates in relation to the primary magnetic field and deforms it periodically in order to generate Alfvén waves which deflect the nanoparticle, whereby the cell membrane of the cell structure is torn up by the nanoparticle and the cell structure is consequently destroyed.

公开(公告)号：US11820959B2

公开(公告)日：2023-11-21

申请号：US17333728

申请日：2021-05-28

Applicant: Natural Extraction Systems, LLC

Inventor： C. Russell Thomas

IPC: C11B1/10 ,  B01D3/10 ,  B01D3/40 ,  B01D5/00 ,  C11B1/04 ,  B01D11/02 ,  A61K41/00 ,  A61K36/185

CPC classification number: C11B1/10 ,  A61K36/185 ,  A61K41/00 ,  B01D3/106 ,  B01D3/40 ,  B01D5/006 ,  B01D11/028 ,  B01D11/0288 ,  C11B1/04

Abstract: Various aspects of the disclosure relate to methods and systems for extracting plant oil from plant material. A system may comprise a microwave emitter, an extraction chamber, and a cooling chamber. Microwave radiation emitted by the microwave emitter may dielectrically heat a microwave absorbing agent, which may heat the plant oil of the plant material. Plant oil of the plant material may be volatized in the extraction chamber and may be directed into the cooling chamber to be condensed.

公开(公告)号：US11771763B2

公开(公告)日：2023-10-03

申请号：US16455077

申请日：2019-06-27

Applicant: EOS Neuroscience, Inc. ,  Wake Forest University Health Sciences

Inventor： Alan Horsager ,  Kenneth Greenberg ,  Benjamin C. Matteo ,  Edward S. Boyden ,  Douglas G. Ririe ,  James C. Eisenach ,  Christian Wentz

IPC: A61N5/06 ,  A61K48/00 ,  A61K49/00 ,  A61K41/00 ,  C07K14/195 ,  C07K14/37 ,  A61K31/7088 ,  C07K14/215

CPC classification number: A61K41/00 ,  A61K31/7088 ,  A61N5/062 ,  C07K14/195 ,  C07K14/215 ,  C07K14/37 ,  C07K2319/60 ,  C12N2750/14143 ,  C12N2810/6027

Abstract: The present invention provides compositions and methods for the selective silencing of neurons in pain pathway by using a combination of inhibitory light-sensitive protein gene transfer and wavelength specific illumination.

公开(公告)号：US20230293739A1

公开(公告)日：2023-09-21

申请号：US18170967

申请日：2023-02-17

Applicant: Plasmology4, Inc.

Inventor： Emilia M. Kulaga

IPC: A61L2/00 ,  A61K41/00 ,  A61L2/18 ,  A61K33/00 ,  A61L2/14 ,  A61K33/243 ,  A61K33/242 ,  A01N59/16 ,  A01N59/20 ,  A61K33/24 ,  A61K33/34 ,  A61K33/38 ,  A61N1/44

CPC classification number: A61L2/0011 ,  A61K41/0052 ,  A61L2/0082 ,  A61L2/18 ,  A61K33/00 ,  A61L2/14 ,  A61K33/243 ,  A61K33/242 ,  A01N59/16 ,  A01N59/20 ,  A61K33/24 ,  A61K33/34 ,  A61K33/38 ,  A61K41/00 ,  A61N1/44 ,  H05H2242/20 ,  H05H2245/50 ,  B22F1/07

Abstract: A method of forming metal nanoparticles includes applying a substance to an area of interest, applying cold plasma to the area of interest, and synthesizing nanoparticles from the substance using the cold plasma in the area of interest, wherein the substance is a solution that contains metal ions, and the nanoparticles synthesized are metallic in nature.

公开(公告)号：US20230277604A1

公开(公告)日：2023-09-07

申请号：US18017934

申请日：2021-07-27

Applicant: JAPAN ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Eijiro MIYAKO

IPC: A61K35/74 ,  A61K49/00 ,  A61N5/06 ,  A61P35/00 ,  A61K41/00

CPC classification number: A61K35/74 ,  A61K49/0004 ,  A61N5/06 ,  A61P35/00 ,  A61K41/00 ,  A61N2005/0659

Abstract: It is an object of the present invention to provide a therapeutic agent or a diagnostic agent for cancer, which has high selectivity to cancer and also has low toxicity or little side effects. According to the present invention, provided is a therapeutic agent or a diagnostic agent for cancer, comprising photosynthetic bacteria.