摘要:
An attachment mechanism and method for attaching or coupling a guide wire to a catheter for re-canalization or opening a passage through an occlusion in a blood vessel is provided. The attachment mechanism generates friction forces against the guide wire to couple the guide wire to a catheter, which design permits a greater force to be used on the guide wire during a re-canalization procedure. The invention also encompasses use of the attachment mechanism in conjunction with active catheters, which have vibration-generating means to oscillate the distal end of the catheter or a component in the distal end of the catheter, to add vibration motion, preferably axial vibration motion, to the increased force that may be applied to the guide wire for purposes of penetrating an occlusion. The methods of the invention relate to methods of attaching the guide wire to the catheter and methods of treating a vessel having a partial or total occlusion.
摘要:
A method of detecting ionizing radiation is provided. The method includes pixelating a semiconductor substrate such that each pixel comprises a central region and a region of variable response, substantially blocking the ionizing radiation from reaching the region of variable response, and receiving the ionizing radiation with the central region.
摘要:
A pixelated detector for detecting photons is provided comprising: a semiconductor crystal; a cathode electrode on a first surface of the crystal; an anode comprising a plurality of anode pixel electrodes on a second surface of the crystal; and a signal generator that receives signals from at least one electrode of the electrodes. When a photon is incident on the detector the signal generator generates a timing signal responsive to signals induced on the at least one electrode by electrons and holes produced by the incident photon and the at least one electrode has a size larger than the size of a single anode pixel electrode.
摘要:
An apparatus, system and method for re-canalization or opening a passage through an occlusion in a blood vessel is provided. The apparatus and method, which are appropriate for both cardiovascular as well as peripheral vessels, use a pulling member and a spring element, for example a compression spring, to oscillate a vibratable member, and the system of the invention includes the apparatus and a control unit to permit the frequency or amplitude of oscillation of the vibratable member to be adjusted. Also provided is a method for oscillating a vibratable member using a pulling member and a spring element. The apparatus and system are useful not only for penetrating a total or partial occlusion, but also to improve deliverability of a catheter through a partially occluded vessel or a tortuous vessel.
摘要:
An attachment mechanism and method for attaching or coupling a guide wire to a catheter for re-canalization or opening a passage through an occlusion in a blood vessel is provided. The attachment mechanism generates friction forces against the guide wire to couple the guide wire to a catheter, which design permits a greater force to be used on the guide wire during a re-canalization procedure. The invention also encompasses use of the attachment mechanism in conjunction with active catheters, which have vibration-generating means to oscillate the distal end of the catheter or a component in the distal end of the catheter, to add vibration motion, preferably axial vibration motion, to the increased force that may be applied to the guide wire for purposes of penetrating an occlusion. The methods of the invention relate to methods of attaching the guide wire to the catheter and methods of treating a vessel having a partial or total occlusion.
摘要:
An attachment mechanism and method for attaching or coupling a guide wire to a catheter for re-canalization or opening a passage through an occlusion in a blood vessel is provided. The attachment mechanism generates friction forces against the guide wire to couple the guide wire to a catheter, which design permits a greater force to be used on the guide wire during a re-canalization procedure. The invention also encompasses use of the attachment mechanism in conjunction with active catheters, which have vibration-generating means to oscillate the distal end of the catheter or a component in the distal end of the catheter, to add vibration motion, preferably axial vibration motion, to the increased force that may be applied to the guide wire for purposes of penetrating an occlusion. The methods of the invention relate to methods of attaching the guide wire to the catheter and methods of treating a vessel having a partial or total occlusion.
摘要:
The present invention relates to apparatus and methods for protecting walls of a body cavity during thermal ablation of tissues near that body cavity, while enabling ultrasound monitoring of the ablation process. Heating protective devices and cooling protective devices are provided. Heatable/coolable ultrasound probes and heatable/coolable independent protective devices compatible with ultrasound imaging by moving ultrasound probes are provided.
摘要:
An apparatus, system and method for re-canalization or opening a passage through an occlusion in a blood vessel is provided. The apparatus and method, which are appropriate for both cardiovascular as well as peripheral vessels, use a pulling member and a spring element, for example a compression spring, to oscillate a vibratable member, and the system of the invention includes the apparatus and a control unit to permit the frequency or amplitude of oscillation of the vibratable member to be adjusted. Also provided is a method for oscillating a vibratable member using a pulling member and a spring element. The apparatus and system are useful not only for penetrating a total or partial occlusion, but also to improve deliverability of a catheter through a partially occluded vessel or a tortuous vessel.
摘要:
A multilayer pixelated detector comprising a plurality of strip array detectors each said strip array detector including a rectangular semiconductor crystal having first and second relatively large parallel planar face surfaces having edges and a thickness; a cathode electrode covering substantially all of said first face surface; and an anode electrode comprising a plurality of anode strip pixels, wherein an anode strip pixel comprises a rectangular electrode having a length and a width. A long dimension of each of said anode strip pixels is parallel to a same edge of said second face surface, the pixelated detectors have contiguous face surfaces and wherein edges of contiguous face surfaces are aligned and wherein anode strip pixels of all pixelated detectors are parallel and electrodes on contiguous surfaces of pixelated detectors are identical and overlap substantially completely.
摘要:
A scintillator, having two faces, for use in medical diagnostic imaging devices, said devices including a plurality of light sensors for converting light generated in said scintillators to electrical signals, processors for converting the electrical signals to images and a monitor for displaying the images, said scintillator including a two dimensional distribution of intrinsic light controllers, said controllers changing the light distribution among the sensors to achieve a desired distribution wherein the light controllers focus the light such that the spread of light to detectors is reduced.