公开(公告)号：US12121341B2

公开(公告)日：2024-10-22

申请号：US17124687

申请日：2020-12-17

申请人： Covidien LP

发明人： Morgan L. Hill ,  Jeetendra S. Bharadwaj ,  Flor De Maria R. Nonalaya ,  Eric W. Larson ,  Kathy E. Rooks ,  Richard A. Willyard ,  Robert J. Behnke, II ,  Nikhil P. Mankar ,  Darren G. Girotto

IPC分类号： A61B5/06 ,  A61B8/00 ,  A61B8/08 ,  A61B8/12 ,  A61B18/18 ,  A61B18/00 ,  A61B34/20 ,  A61B90/00 ,  A61B90/98

CPC分类号： A61B5/066 ,  A61B8/0841 ,  A61B8/12 ,  A61B8/4254 ,  A61B8/4272 ,  A61B8/4444 ,  A61B8/52 ,  A61B18/1815 ,  A61B2018/00023 ,  A61B2018/00577 ,  A61B2018/00642 ,  A61B2018/00678 ,  A61B2018/00708 ,  A61B2018/00791 ,  A61B2018/00875 ,  A61B2018/00982 ,  A61B2018/00988 ,  A61B2018/1892 ,  A61B2034/2051 ,  A61B2090/3782 ,  A61B90/98

摘要： A system includes an energy source configured to generate therapeutic energy, a treatment probe, an ultrasound imaging device configured to generate ultrasound images, a second tracking sensor configured to track a location of the ultrasound imaging device, and a tracking system configured to receive location information from the first and second tracking sensors and to overlay the ultrasound images with a graphical representation of the treatment probe on a display based on the location information. The treatment probe includes an antenna configured to treat tissue with the therapeutic energy and a first tracking sensor integrated in the antenna and configured to track a location of a distal tip of the antenna.

公开(公告)号：US12121298B2

公开(公告)日：2024-10-22

申请号：US16943206

申请日：2020-07-30

申请人： J. MORITA MFG. CORP.

发明人： Yoshiteru Tamura ,  Yoshihide Okagami ,  Akihito Hongo ,  Katsumi Hiyoshi ,  Haruhiko Murakami

IPC分类号： A61B18/20 ,  A61B1/12 ,  G02B23/24 ,  A61B18/00 ,  A61B18/22 ,  A61B90/00

CPC分类号： A61B18/201 ,  A61B1/12 ,  G02B23/2476 ,  A61B2018/00011 ,  A61B2018/00023 ,  A61B2018/00642 ,  A61B2018/00863 ,  A61B2018/00982 ,  A61B18/22 ,  A61B2018/2247 ,  A61B2090/064

摘要： An abnormality detection system for highly precise detection of an abnormality in a laser treatment device includes a laser transmission tube coupled with a laser treatment unit, oscillating laser light, a discharge-side water pressure sensor, and a water pressure detection liquid surface level meter detecting a change in a pressure of cooling water flowing through forward-direction and a backward-direction spaces in the laser transmission tube. The laser transmission tube includes a hollow wavelength path having a lightguide space formed in a longitudinal direction, and an outer case enclosing an outer circumferential surface of the hollow waveguide path and extending in the longitudinal direction. The discharge-side water pressure sensor and the water pressure detection liquid surface level meter detect the change in the pressure of the cooling water flowing through in a forward-direction space and a backward-direction space to detect any abnormality.

公开(公告)号：US20240341849A1

公开(公告)日：2024-10-17

申请号：US18750990

申请日：2024-06-21

申请人： NANOSPECTRA BIOSCIENCES, INC.

发明人： Glenn Patrick Goodrich ,  Jon Schwartz ,  Andrew Mark Murphy

IPC分类号： A61B18/28 ,  A61B17/34 ,  A61B18/00 ,  A61B18/04 ,  A61B18/20 ,  A61B18/22 ,  A61B18/24 ,  A61K9/00 ,  A61K9/51 ,  A61K41/00 ,  A61M25/06 ,  A61N5/06 ,  A61N5/067

CPC分类号： A61B18/28 ,  A61B17/3415 ,  A61B18/22 ,  A61B18/24 ,  A61K9/0009 ,  A61K9/0019 ,  A61K9/5115 ,  A61K41/0028 ,  A61K41/0052 ,  A61M25/0662 ,  A61N5/0603 ,  A61N5/062 ,  A61B2018/00011 ,  A61B2018/00023 ,  A61B2018/00547 ,  A61B2018/00577 ,  A61B2018/00589 ,  A61B18/04 ,  A61B2018/2005 ,  A61B2018/2205 ,  A61B2018/2261 ,  A61N5/0625 ,  A61N2005/063 ,  A61N2005/0659 ,  A61N5/067

摘要： Various methods, systems, and devices for treating tissue ablation are disclosed. Some embodiments disclosed herein pertain to methods of treating tumors, systems used for irradiating tissue and tumors with electromagnetic radiation, components and devices of that system, and kits for providing systems used for irradiating tissue and tumors with electromagnetic radiation. In some embodiments, the system provides sub-ablative infrared radiation that is absorbed by nanoparticles. In some embodiments, the nanoparticles absorb the radiation converting it into heat energy. In some embodiments, though the infrared radiation itself may be sub-ablative, the heat energy generated by the nanoparticles is sufficient to cause thermal coagulation, hyperthermia, and/or tissue ablation.

公开(公告)号：US20240293683A1

公开(公告)日：2024-09-05

申请号：US18656122

申请日：2024-05-06

申请人： Alpheus Medical, Inc.

发明人： Vijay AGARWAL ,  Braden ELIASON ,  Jeremy LING

IPC分类号： A61N7/00 ,  A61B17/00 ,  A61B17/32 ,  A61B18/00 ,  A61F7/00 ,  A61F7/02 ,  A61K9/00 ,  A61K31/197 ,  A61K41/00 ,  A61M21/00 ,  A61M21/02 ,  A61P35/00 ,  B06B1/02 ,  B06B1/06

CPC分类号： A61N7/00 ,  A61F7/0085 ,  A61K9/0053 ,  A61K31/197 ,  A61K41/0033 ,  A61K41/0061 ,  A61M21/02 ,  A61P35/00 ,  B06B1/0207 ,  B06B1/0622 ,  A61B2017/00084 ,  A61B2017/320069 ,  A61B2018/00023 ,  A61B2018/00446 ,  A61F2007/0056 ,  A61F2007/0096 ,  A61F2007/0288 ,  A61M2021/0027 ,  A61M2021/005 ,  A61N2007/003 ,  A61N2007/006 ,  A61N2007/0073 ,  A61N2007/0078 ,  A61N2007/0082 ,  A61N2007/0095 ,  B06B2201/76

摘要： Disclosed are systems and methods of producing ultrasound waves for providing sonodynamic therapy. The method includes coupling a sonodynamic therapy device with an array of piezoelectric transducer elements to a skin surface. A controller is configured to generate an electrical drive signal to produce ultrasound waves to activate a sonosensitizer in a treatment region without damaging healthy cells in the treatment region.

公开(公告)号：US20240252230A1

公开(公告)日：2024-08-01

申请号：US18462898

申请日：2023-09-07

申请人： Cosman Instruments, LLC

发明人： Eric R. Cosman, JR. ,  Eric R. Cosman, SR.

IPC分类号： A61B18/14 ,  A61B17/34 ,  A61B18/00

CPC分类号： A61B18/14 ,  A61B17/3421 ,  A61B2018/00023 ,  A61B2018/00071 ,  A61B2018/00577 ,  A61B2018/00791 ,  A61B2018/1465 ,  A61B2018/1475

摘要： An RF electrode can have a straight shaft to generate an RF heat lesion that is asymmetric about the central axis of the cannula through which the RF electrode is introduced into bodily tissue.

公开(公告)号：US20240238042A1

公开(公告)日：2024-07-18

申请号：US18289510

申请日：2022-05-06

申请人： CURATIVE CANCER TREATMENT BY HEAT (CCTBH) AB

发明人： Hans WIKSELL

IPC分类号： A61B18/16 ,  A61B18/00 ,  A61B18/12

CPC分类号： A61B18/16 ,  A61B18/1206 ,  A61B2018/00023 ,  A61B2018/00077 ,  A61B2018/00083 ,  A61B2018/00184 ,  A61B2018/00577 ,  A61B2018/00648 ,  A61B2018/00672 ,  A61B2018/00708 ,  A61B2018/00714 ,  A61B2018/1253 ,  A61B2018/126 ,  A61B2018/167

摘要： A system for curative RFA treatment of a treatment volume including at least a part of a cancer tumor by applying RF energy between an electrode arranged on an uninsulated ablating portion of an RF probe and another electrode is provided. The system includes: a control arrangement; an RF probe, including an uninsulated ablating portion; a temperature measuring arrangement, arranged to measure an RF probe temperature and provide estimations of the treatment volume temperature to the control arrangement; a cooling arrangement, controlled by the control arrangement to cool the RF probe; and an RF generating arrangement, controlled by the control arrangement to, based on the estimated treatment volume temperature, supply the amount of RF energy to the RF probe that is needed for a desired treatment volume temperature to be maintained. The control arrangement monitors the RF energy supplied by the RF generating arrangement to the RF probe, and turns off the RF generating arrangement when there is no longer any substantial lowering of the output power.

公开(公告)号：US20240225722A1

公开(公告)日：2024-07-11

申请号：US18431250

申请日：2024-02-02

申请人： INMODE LTD

发明人： Jonathan B. Parmer

IPC分类号： A61B18/14 ,  A61B18/00 ,  A61B18/12 ,  A61B18/18 ,  A61N7/02

CPC分类号： A61B18/1485 ,  A61B18/18 ,  A61N7/022 ,  A61B2018/00023 ,  A61B2018/00559 ,  A61B2018/00702 ,  A61B2018/00791 ,  A61B2018/00875 ,  A61B18/1206

摘要： This invention relates generally to apparatus and methods for tightening tissue of the female genitalia by heating targeted connective tissue with radiant energy, while cooling the mucosal epithelial surface over the target tissue to protect it from the heat. Embodiments include a treatment tip that comprises both an energy delivery element and a cooling mechanism. As the treatment tip contacts the epithelial mucosa, the tip cools the mucosa by contact, and delivers energy through the epithelium to the underlying tissue, thereby creating a reverse thermal gradient. The effect of the applied heat is to remodel genital tissue by tightening it. Such remodeling may include a tighter vagina and a tighter introitus. The tightening may be a consequence of thermal denaturation of collagen as well as a longer term healing response in the tissue that includes an increased deposition of collagen.

公开(公告)号：US20240206968A1

公开(公告)日：2024-06-27

申请号：US18598108

申请日：2024-03-07

申请人： Medtronic Ireland Manufacturing Unlimited Company

发明人： Scott Raymond Smith

IPC分类号： A61B18/14 ,  A61B8/08 ,  A61B8/12 ,  A61B17/00 ,  A61B17/122 ,  A61B17/32 ,  A61B18/00 ,  A61B18/02 ,  A61B18/04 ,  A61B18/06 ,  A61B18/16 ,  A61B18/18 ,  A61B18/22 ,  A61B18/24 ,  A61M25/01 ,  A61M25/09 ,  A61N7/00

CPC分类号： A61B18/1492 ,  A61B17/122 ,  A61B17/320068 ,  A61B18/02 ,  A61B18/06 ,  A61B18/16 ,  A61M25/0147 ,  A61B8/12 ,  A61B8/485 ,  A61B2017/00402 ,  A61B2017/00867 ,  A61B2017/320069 ,  A61B2018/00023 ,  A61B2018/00047 ,  A61B2018/00214 ,  A61B2018/0022 ,  A61B2018/00267 ,  A61B2018/00279 ,  A61B2018/00285 ,  A61B2018/00404 ,  A61B2018/00434 ,  A61B2018/00529 ,  A61B2018/00577 ,  A61B2018/00821 ,  A61B2018/00875 ,  A61B2018/0212 ,  A61B2018/048 ,  A61B2018/068 ,  A61B2018/1425 ,  A61B2018/1435 ,  A61B2018/1467 ,  A61B2018/1475 ,  A61B18/1815 ,  A61B2018/1861 ,  A61B18/22 ,  A61B18/24 ,  A61B2218/007 ,  A61M25/09 ,  A61N2007/0021 ,  A61N2007/0043

摘要： According to various embodiments, systems, devices and methods for modulating targeted nerve fibers (e.g., hepatic neuromodulation) or other tissue are provided. The systems may be configured to access tortuous anatomy of or adjacent hepatic vasculature. The systems may be configured to target nerves surrounding (e.g., within adventitia of or within perivascular space of) an artery or other blood vessel, such as the common hepatic artery.

公开(公告)号：US11986235B2

公开(公告)日：2024-05-21

申请号：US14917243

申请日：2014-09-12

申请人： Fractyl Health, Inc.

发明人： Jay Caplan ,  Philip S. Levin ,  R. Maxwell Flaherty ,  J. Christopher Flaherty

IPC分类号： A61B18/14 ,  A61B8/12 ,  A61B18/00

CPC分类号： A61B18/1492 ,  A61B8/12 ,  A61B2018/00023 ,  A61B2018/00041 ,  A61B2018/00166 ,  A61B2018/0022 ,  A61B2018/00482 ,  A61B2018/00494 ,  A61B2018/00577 ,  A61B2018/00714

摘要： A system for treating a patient comprises an elongate shaft, an expandable reservoir and a fluid delivery assembly. The elongate shaft comprises a distal portion and is constructed and arranged to be introduced into a gastrointestinal lumen. The expandable reservoir is positioned on the elongate shaft distal portion and is constructed and arranged to receive a first fixed amount of ablative fluid and to deliver a first thermal dose of energy to a first portion of target tissue. The fluid delivery assembly is in fluid communication with the expandable reservoir and is constructed and arranged to deliver the first fixed amount of ablative fluid to the expandable reservoir. Devices and methods for treating tissue of a patient are also provided.

公开(公告)号：US11980777B2

公开(公告)日：2024-05-14

申请号：US18214386

申请日：2023-06-26

申请人： Alpheus Medical, Inc.

发明人： Vijay Agarwal ,  Braden Eliason ,  Jeremy Ling

IPC分类号： A61N7/00 ,  A61B17/00 ,  A61B17/32 ,  A61B18/00 ,  A61F7/00 ,  A61F7/02 ,  A61K9/00 ,  A61K31/197 ,  A61K41/00 ,  A61P35/00 ,  B06B1/02 ,  B06B1/06

CPC分类号： A61N7/00 ,  A61F7/0085 ,  A61K9/0053 ,  A61K31/197 ,  A61K41/0033 ,  A61K41/0061 ,  A61P35/00 ,  B06B1/0207 ,  B06B1/0622 ,  A61B2017/00084 ,  A61B2017/320069 ,  A61B2018/00023 ,  A61B2018/00446 ,  A61F2007/0056 ,  A61F2007/0096 ,  A61F2007/0288 ,  A61N2007/003 ,  A61N2007/006 ,  A61N2007/0073 ,  A61N2007/0078 ,  A61N2007/0082 ,  A61N2007/0095 ,  B06B2201/76

摘要： Disclosed are methods of producing randomized ultrasound waves for providing sonodynamic therapy. The method includes coupling a sonodynamic therapy device with an array of piezoelectric transducer elements to a skin surface. A controller is configured to generate an electrical drive signal to produce ultrasound waves to activate a sonosensitizer in a treatment region without damaging healthy cells in the treatment region.