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    PREDICTING THE MOLECULAR COMPLEXITY OF SEQUENCING LIBRARIES
    1.
    发明申请
    PREDICTING THE MOLECULAR COMPLEXITY OF SEQUENCING LIBRARIES 审中-公开
    预测序列分析的复杂性

    公开(公告)号：US20140324359A1

    公开(公告)日：2014-10-30

    申请号：US14262356

    申请日：2014-04-25

    Applicant: Andrew D. Smith ,  Timothy P. Daley

    Inventor： Andrew D. Smith ,  Timothy P. Daley

    IPC: G06F19/24

    CPC classification number: G16B40/00 ,  G16B30/00

    Abstract: Predicting the molecular complexity of a genomic sequencing library is a critical but difficult problem in modern sequencing applications. Methods to determine how deeply to sequence to achieve complete coverage or to predict the benefits of additional sequencing are lacking. We introduce an empirical Bayesian method to accurately characterize the molecular complexity of a DNA sample for almost any sequencing application based on limited preliminary sequencing.

    Abstract translation: 预测基因组测序文库的分子复杂性是现代测序应用中关键但难点的问题。 确定实现完全覆盖或预测附加测序的好处的顺序有多深入的方法是缺乏的。 我们引入一种经验贝叶斯方法，以准确地表征基于有限的初步测序的几乎任何测序应用的DNA样品的分子复杂性。

    MATERIALS HANDLING VEHICLE
    4.
    发明申请
    MATERIALS HANDLING VEHICLE 有权
    材料处理车辆

    公开(公告)号：US20080202857A1

    公开(公告)日：2008-08-28

    申请号：US11928227

    申请日：2007-10-30

    Applicant: Lucas B. Waltz ,  William C. Jones ,  Andrew D. Smith

    Inventor： Lucas B. Waltz ,  William C. Jones ,  Andrew D. Smith

    IPC: B66F9/06 ,  B66F9/20

    CPC classification number: B66F17/003 ,  B60K1/04 ,  B60Y2200/15 ,  B66F9/07545 ,  B66F9/07572 ,  B66F9/07595

    Abstract: A materials handling vehicle is provided comprising a frame including a longitudinal centerline and an operator compartment; first and second front wheels coupled to the frame; a rear steer wheel assembly coupled to the frame; mast apparatus coupled to the frame and including a pair of forks; and a battery associated with the frame and having a center of gravity. The battery is preferably positioned such that the battery center of gravity is laterally offset from the longitudinal center line. A stability triangle for the vehicle is defined by a first point at the first front wheel, a second point at the second front wheel and a third point at the rear steer wheel assembly. Preferably, the stability triangle defines a scalene triangle.

    Abstract translation: 提供了一种材料处理车辆，其包括：框架，其包括纵向中心线和操作室; 第一和第二前轮联接到框架; 耦合到框架的后转向轮组件; 桅杆装置联接到框架并且包括一对叉子; 以及与该框架相关并具有重心的电池。 优选地，电池被定位成使得电池重心横向偏离纵向中心线。 用于车辆的稳定性三角形由第一前轮处的第一点，第二前轮处的第二点和后转向轮组件的第三点限定。 优选地，稳定性三角形定义了斜角三角形。

    Multiplexed amplifier
    7.
    发明授权
    Multiplexed amplifier 有权
    多路复用放大器

    公开(公告)号：US07253701B2

    公开(公告)日：2007-08-07

    申请号：US10999849

    申请日：2004-11-30

    Applicant: Andrew D. Smith ,  Barry R. Allen

    Inventor： Andrew D. Smith ,  Barry R. Allen

    IPC: H01P5/12

    CPC classification number: H01P1/2135

    Abstract: Multiple sensor signals are used to modulate an equal number of frequency-spaced carrier signals in a directional parametric upconverting amplifier. Basically, the carrier signals are separated in a cascaded or parallel configuration of narrow frequency passbands, which also modulate the carrier signals with low-frequency sensor signals. The modulated carrier signals are multiplexed and output over a single signal path, thereby reducing power dissipation. Preferably implemented in superconducting circuitry, the multiplexed amplifier facilitates multiplexing of as many as hundreds of sensor signals and achieves both amplification and upconverting with minimal dissipation of power.

    Abstract translation: 多个传感器信号用于在方向参数上变频放大器中调制相等数量的频间隔载波信号。 基本上，载波信号以窄频率通带的级联或并联配置分离，窄频率通带也用低频传感器信号调制载波信号。 经调制的载波信号被复用并通过单个信号路径输出，从而减少功耗。 优选地，在超导电路中实现，多路复用放大器有助于多达数百个传感器信号的复用，并且以最小的功率消耗实现放大和上变频。

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