公开(公告)号：US20110098200A1

公开(公告)日：2011-04-28

申请号：US10526475

申请日：2003-09-04

申请人： Gregory Martin Arndt ,  Murray Cairns ,  Nham Tran ,  Angela Lai

发明人： Gregory Martin Arndt ,  Murray Cairns ,  Nham Tran ,  Angela Lai

IPC分类号： C40B50/06 ,  C12P19/34 ,  C12N15/64 ,  C12Q1/68 ,  C12N15/63 ,  C12N5/071

CPC分类号： C12N15/10 ,  C12N15/111 ,  C12N15/1132 ,  C12N15/1135 ,  C12N2310/111 ,  C12N2310/14 ,  C12N2310/53 ,  C12N2330/30

摘要： The present invention provides methods of producing dsDNA molecules that can be used to mediate RNA interference (RNAi). These methods include the production of hairpin DNAs including random sequences, and the use of convergent promoters to co-express sense and antisense RNAs. As such, the invention allows the production of random short hairpin RNA (shRNA) and a small interfering RNA (siRNA) expression libraries for forward genetic screening.

摘要翻译： 本发明提供了可用于介导RNA干扰（RNAi）的dsDNA分子的生产方法。 这些方法包括产生包含随机序列的发夹DNA，以及使用会聚启动子共表达正义和反义RNA。 因此，本发明允许产生用于前向遗传筛选的随机短发夹RNA（shRNA）和小干扰RNA（siRNA）表达文库。

公开(公告)号：US20070268164A1

公开(公告)日：2007-11-22

申请号：US11825705

申请日：2007-07-09

申请人： Angela Lai ,  Howard Chartock ,  Christopher Pirazzi ,  Steve Chen ,  Jody Shapiro ,  James Hoddie

发明人： Angela Lai ,  Howard Chartock ,  Christopher Pirazzi ,  Steve Chen ,  Jody Shapiro ,  James Hoddie

IPC分类号： H03M7/00

CPC分类号： H04N21/2404 ,  H04N7/17318 ,  H04N19/40 ,  H04N21/23106 ,  H04N21/234309 ,  H04N21/23439 ,  H04N21/2405 ,  H04N21/2408 ,  H04N21/2743 ,  H04N21/4622 ,  H04N21/6125 ,  H04N21/6336 ,  H04N21/6379 ,  H04N21/643 ,  H04N21/64769 ,  H04N21/8193

摘要： A method for delivering media content over a network includes transcoding the media content to generate multiple copies of the media content, each of the multiple copies having a different destination type or a different source type or both, storing the multiple copies in a cache, receiving requests for the media content, and selecting and delivering a copy of one of the multiple copies in response to each of the requests. A further method for providing media content transcoding services includes fetching media content, selecting one of multiple transcoders for transcoding from multiple source types to multiple destination types, wherein the one transcoder is selected based at least on the destination type, sending the media content to the selected transcoder, transcoding the media content to the destination type, thereby generating transcoded media content, and transmitting the transcoded media content.

公开(公告)号：US20070043808A1

公开(公告)日：2007-02-22

申请号：US11586133

申请日：2006-10-25

申请人： Giovanni Agnoli ,  Christopher Pirazzi ,  Howard Chartock ,  Steve Chen ,  Harry Chomsky ,  Angela Lai ,  Kerrick Lindsey ,  David Pawson ,  Jody Shapiro ,  Daniel Weaver

发明人： Giovanni Agnoli ,  Christopher Pirazzi ,  Howard Chartock ,  Steve Chen ,  Harry Chomsky ,  Angela Lai ,  Kerrick Lindsey ,  David Pawson ,  Jody Shapiro ,  Daniel Weaver

IPC分类号： G06F15/16

CPC分类号： H04L65/602 ,  H04L29/06 ,  H04L29/06027 ,  H04L65/4084 ,  H04L65/607 ,  H04L67/1002 ,  H04L67/1008 ,  H04L67/1012 ,  H04L67/1029 ,  H04L67/2814 ,  H04L67/2823 ,  H04L67/2847 ,  H04L69/329 ,  H04N21/23103 ,  H04N21/23106 ,  H04N21/2343 ,  H04N21/2405 ,  H04N21/6581 ,  H04N21/6582

摘要： A system, method, and computer program product for publishing transcoded media content in response to publishing service requests from end users. A user request for media content, is processed intelligently, either by directing the processing of the request to one of a set of transcoding servers so as to effectively balance the load among the servers, or by directing the processing of the request to an appropriate alternative means for satisfying the request. Transcoding tasks can be prioritized. Moreover, the current load on any particular transcoding server can be monitored in conjunction with determination of the load to be created by a transcoding task, in order to facilitate server selection. Transcoding can be performed on-demand or in a batch mode. Alternatively, a request can be satisfied by distributing media content that has already been transcoded and is resident in cache memory in anticipation of such requests.

摘要翻译： 一种系统，方法和计算机程序产品，用于响应于最终用户的发布服务请求，发布转码媒体内容。 通过将请求的处理指向一组代码转换服务器之一来有效地平衡服务器之间的负载，或通过将请求的处理引导到适当的替代方案来对用户对媒体内容的请求进行智能处理 满足要求的手段。 转码任务可以优先。 此外，可以结合确定由代码转换任务创建的负载来监视任何特定转码服务器上的当前负载，以便于服务器选择。 转码可以按需或批量模式进行。 或者，可以通过分发已经被转码的媒体内容并且预期到这样的请求而驻留在高速缓冲存储器中来满足请求。

公开(公告)号：US06317134B1

公开(公告)日：2001-11-13

申请号：US08914897

申请日：1997-08-20

申请人： Bent Hagemark ,  Angela Lai ,  Kevin Meier ,  Jonathan Wesener ,  Brian Beach ,  John Wiltse Carpenter ,  Terrence Crane

发明人： Bent Hagemark ,  Angela Lai ,  Kevin Meier ,  Jonathan Wesener ,  Brian Beach ,  John Wiltse Carpenter ,  Terrence Crane

IPC分类号： G06F15167

CPC分类号： G01B3/56 ,  G01B5/24

摘要： A computer system having a shared system memory, and system software in the computer system, are described herein. The computer system has a general purpose, shared system memory that is used for all processing, including video input/output operations, image conversion operations, and rendering operations. In operation, a digital media (DM) Pbuffer is created. The DM Pbuffer is aliased as a DM buffer in the system memory. This is done by storing in a color buffer identifier of the DM Pbuffer an identifier of the DM buffer. Thereafter, all graphical rendering operations directed to the DM Pbuffer are actually performed using the DM buffer.

摘要翻译： 本文描述了具有共享系统存储器的计算机系统和计算机系统中的系统软件。 计算机系统具有用于所有处理的通用共享系统存储器，包括视频输入/输出操作，图像转换操作和渲染操作。 在操作中，创建了数字媒体（DM）Pbuffer。 DM Pbuffer在系统存储器中作为DM缓冲区进行混叠。 这通过将DM缓冲器的颜色缓冲器标识符存储在DM缓冲器的标识符中来完成。 此后，实际上使用DM缓冲器执行针对DM Pbuffer的所有图形呈现操作。

公开(公告)号：US6070002A

公开(公告)日：2000-05-30

申请号：US713419

申请日：1996-09-13

申请人： Bent Hagemark ,  Angela Lai ,  Kevin Meier ,  Jonathan Wesener ,  Brian Beach ,  John Wiltse Carpenter

发明人： Bent Hagemark ,  Angela Lai ,  Kevin Meier ,  Jonathan Wesener ,  Brian Beach ,  John Wiltse Carpenter

IPC分类号： G06T1/60 ,  G06F17/00

CPC分类号： G06T1/60

摘要： A computer system having a shared system memory, and system software in the computer system, are described herein. One or more user applications execute in the computer system. The computer system has a general purpose, shared system memory that is used for all processing, including video input/output operations and image conversion operations. The computer system also has a multimedia access and control module (MACM), which is the input/output interface between the computer system and the external world. In operation, the MACM receives, at one of its video input ports, video data comprising a video image (such as a frame or a field). The MACM stores the video image in a first buffer contained in a first buffer pool of the system memory. The first buffer pool was previously created by a user application. The user application previously associated the first buffer pool with the MACM's video input port. A video imaging and compression module (VICM) performs image conversion operations. Each user application creates one or more converter contexts of the VICM. Each converter context is capable of performing an image conversion operation. In operation, a converter context of the VICM performs an image conversion operation on the video image stored in the first buffer. Then, the converter context stores the results of the image conversion operation in a second buffer contained in a second buffer pool of the system memory. The second buffer pool is also associated with the user application.

摘要翻译： 本文描述了具有共享系统存储器的计算机系统和计算机系统中的系统软件。 一个或多个用户应用程序在计算机系统中执行。 计算机系统具有用于所有处理的通用共享系统存储器，包括视频输入/输出操作和图像转换操作。 计算机系统还具有多媒体访问和控制模块（MACM），它是计算机系统与外部世界之间的输入/输出接口。 在操作中，MACM在其一个视频输入端口处接收包括视频图像（诸如帧或场）的视频数据。 MACM将视频图像存储在包含在系统存储器的第一缓冲池中的第一缓冲器中。 第一个缓冲池以前是由用户应用程序创建的。 用户应用程序以前将第一个缓冲池与MACM的视频输入端口相关联。 视频成像和压缩模块（VICM）执行图像转换操作。 每个用户应用程序创建一个或多个VICM的转换器上下文。 每个转换器上下文能够执行图像转换操作。 在操作中，VICM的转换器上下文对存储在第一缓冲器中的视频图像执行图像转换操作。 然后，转换器上下文将图像转换操作的结果存储在包含在系统存储器的第二缓冲池中的第二缓冲器中。 第二个缓冲池也与用户应用程序相关联。

公开(公告)号：US20070067390A1

公开(公告)日：2007-03-22

申请号：US11586205

申请日：2006-10-25

申请人： Giovanni Agnoli ,  Christopher Pirazzi ,  Howard Chartock ,  Steve Chen ,  Harry Chomsky ,  Angela Lai ,  Kerrick Lindsey ,  David Pawson ,  Jody Shapiro ,  Daniel Weaver

发明人： Giovanni Agnoli ,  Christopher Pirazzi ,  Howard Chartock ,  Steve Chen ,  Harry Chomsky ,  Angela Lai ,  Kerrick Lindsey ,  David Pawson ,  Jody Shapiro ,  Daniel Weaver

IPC分类号： G06F15/16

CPC分类号： H04L65/602 ,  H04L29/06 ,  H04L29/06027 ,  H04L65/4084 ,  H04L65/607 ,  H04L67/1002 ,  H04L67/1008 ,  H04L67/1012 ,  H04L67/1029 ,  H04L67/2814 ,  H04L67/2823 ,  H04L67/2847 ,  H04L69/329 ,  H04N21/23103 ,  H04N21/23106 ,  H04N21/2343 ,  H04N21/2405 ,  H04N21/6581 ,  H04N21/6582

摘要： A system, method, and computer program product for publishing transcoded media content in response to publishing service requests from end users. A user request for media content, is processed intelligently, either by directing the processing of the request to one of a set of transcoding servers so as to effectively balance the load among the servers, or by directing the processing of the request to an appropriate alternative means for satisfying the request. Transcoding tasks can be prioritized. Moreover, the current load on any particular transcoding server can be monitored in conjunction with determination of the load to be created by a transcoding task, in order to facilitate server selection. Transcoding can be performed on-demand or in a batch mode. Alternatively, a request can be satisfied by distributing media content that has already been transcoded and is resident in cache memory in anticipation of such requests.

摘要翻译： 一种系统，方法和计算机程序产品，用于响应于最终用户的发布服务请求，发布转码媒体内容。 通过将请求的处理指向一组代码转换服务器之一来有效地平衡服务器之间的负载，或通过将请求的处理引导到适当的替代方案来对用户对媒体内容的请求进行智能处理 满足要求的手段。 转码任务可以优先。 此外，可以结合确定由代码转换任务创建的负载来监视任何特定转码服务器上的当前负载，以便于服务器选择。 转码可以按需或批量模式进行。 或者，可以通过分发已经被转码的媒体内容并且预期到这样的请求而驻留在高速缓冲存储器中来满足请求。