公开(公告)号：US08837803B2

公开(公告)日：2014-09-16

申请号：US12982422

申请日：2010-12-30

申请人： Zhizhou Wang ,  Min Xie ,  Anil Patil ,  Chong Chen ,  Shaohong Wang ,  Cord Mueller

发明人： Zhizhou Wang ,  Min Xie ,  Anil Patil ,  Chong Chen ,  Shaohong Wang ,  Cord Mueller

IPC分类号： G06K9/00 ,  G01N33/49

CPC分类号： G01N33/49

摘要： A method and apparatus for determining a cell volume of a red blood cell is provided. The method includes the steps of: a) depositing a sample into an analysis chamber, the chamber defined by an first panel interior surface, a second panel interior surface, and a known or determinable height, which height is such that at least one red blood cell subject to a sphering agent assumes a partially compressed spherical shape in contact with the interior surfaces; b) imaging the at least one partially compressed spherical red blood cell contacting the interior surfaces, and producing image signals; c) determining a radius of the partially compressed spherical red blood cell from the image signals; and d) determining a volume of the imaged red blood cell using the determined radius.

摘要翻译： 提供了一种用于确定红细胞的细胞体积的方法和装置。 该方法包括以下步骤：a）将样品沉积到分析室中，所述室由第一面板内表面，第二面板内表面和已知或可确定的高度限定，所述高度使得至少一个红血 经受球形剂的细胞呈现与内表面接触的部分压缩球形; b）对与内表面接触的至少一个部分压缩的球形红细胞进行成像，并产生图像信号; c）根据图像信号确定部分压缩的球形红细胞的半径; 以及d）使用确定的半径来确定成像的红细胞的体积。

公开(公告)号：US20110164803A1

公开(公告)日：2011-07-07

申请号：US12982422

申请日：2010-12-30

申请人： Zhizhou Wang ,  Min Xie ,  Anil Patil ,  Chong Chen ,  Shaohong Wang ,  Cord Mueller

发明人： Zhizhou Wang ,  Min Xie ,  Anil Patil ,  Chong Chen ,  Shaohong Wang ,  Cord Mueller

IPC分类号： G06K9/00

CPC分类号： G01N33/49

摘要： A method and apparatus for determining a cell volume of a red blood cell is provided. The method includes the steps of: a) depositing a sample into an analysis chamber, the chamber defined by an first panel interior surface, a second panel interior surface, and a known or determinable height, which height is such that at least one red blood cell subject to a sphering agent assumes a partially compressed spherical shape in contact with the interior surfaces; b) imaging the at least one partially compressed spherical red blood cell contacting the interior surfaces, and producing image signals; c) determining a radius of the partially compressed spherical red blood cell from the image signals; and d) determining a volume of the imaged red blood cell using the determined radius.

摘要翻译： 提供了一种用于确定红细胞的细胞体积的方法和装置。 该方法包括以下步骤：a）将样品沉积到分析室中，所述室由第一面板内表面，第二面板内表面和已知或可确定的高度限定，所述高度使得至少一个红血 经受球形剂的细胞呈现与内表面接触的部分压缩球形; b）对与内表面接触的至少一个部分压缩的球形红细胞进行成像，并产生图像信号; c）根据图像信号确定部分压缩的球形红细胞的半径; 以及d）使用确定的半径来确定成像的红细胞的体积。