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1.发明授权Pyrimidinyl and 1,3,5-triazinyl benzimidazoles and their use in cancer therapy 有权嘧啶基和1,3,5-三嗪基苯并咪唑及其在癌症治疗中的应用公开(公告)号：US08486939B2
公开(公告)日：2013-07-16
申请号：US12831128
申请日：2010-07-06
IPC分类号： A61K31/535 , C07D413/14
CPC分类号： C07D487/04 , C07D401/14 , C07D403/04 , C07D403/14
摘要： Provided herein are pyrimidinyl and 1,3,5-triazinyl benzimidazoles of Formula I, and their pharmaceutical compositions, preparation, and use as agents or drugs for cancer therapy, either alone or in combination with radiation and/or other anticancer drugs.
摘要翻译： 本文提供式I的嘧啶基和1,3,5-三嗪基苯并咪唑及其药物组合物，制剂和用作癌症治疗的药物或药物，单独或与辐射和/或其它抗癌药物组合。
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2.发明授权公开(公告)号：US08461158B2
公开(公告)日：2013-06-11
申请号：US12748251
申请日：2010-03-26
申请人： Gordon William Rewcastle , Swarnalatha Akuratiya Gamage , Jack Urquhart Flanagan , Anna Claire Giddens , Kit Yee Tsang
发明人： Gordon William Rewcastle , Swarnalatha Akuratiya Gamage , Jack Urquhart Flanagan , Anna Claire Giddens , Kit Yee Tsang
IPC分类号： A61K31/535 , C07D251/54
CPC分类号： C07D491/08 , A61K31/5355 , A61K31/541 , A61K45/06 , C07D403/04 , C07D403/14 , C07D413/14 , C07D473/34 , C07D487/04 , C07D498/08
摘要： Provided herein are pyrimidinyl and 1,3,5-triazinyl benzimidazole sulfonamides, e.g., compounds of Formulae IA, IB, and IC, and their pharmaceutical compositions, preparation, and use as agents or drugs for cancer therapy, either alone or in combination with radiation and/or other anticancer drugs.
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公开(公告)号：US20120225862A1
公开(公告)日：2012-09-06
申请号：US13384978
申请日：2010-07-21
申请人： Patrick D. Sutphin , Denise A. Chan , Sandra Turcotte , William Alexander Denny , Michael Patrick Hay , Anna Claire Giddens , Muriel Marie Bonnet , Amato J. Giaccia
发明人： Patrick D. Sutphin , Denise A. Chan , Sandra Turcotte , William Alexander Denny , Michael Patrick Hay , Anna Claire Giddens , Muriel Marie Bonnet , Amato J. Giaccia
IPC分类号： A61K31/4402 , C07D215/38 , A61K31/47 , C07D241/20 , A61K31/4965 , A61P35/04 , A61K31/505 , C07D401/12 , A61K31/496 , A61K31/55 , A61P35/00 , C07D213/74 , C07D239/42
CPC分类号： A61K31/33 , C07C2603/74 , C07D213/75 , C07D213/89 , C07D215/38 , C07D231/40 , C07D239/42 , C07D241/20 , C07D277/46 , C07D401/10 , C07D413/10 , C07D417/10
摘要： Provided are certain heteroaryl benzamides, compositions, and methods of their manufacture and use.
摘要翻译： 提供某些杂芳基苯甲酰胺，组合物及其制备和使用的方法。
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4.发明申请PYRIMIDINYL AND 1,3,5-TRIAZINYL BENZIMIDAZOLE SULFONAMIDES AND THEIR USE IN CANCER THERAPY 有权吡嗪二酮和1,3,5-三嗪基苯并咪唑磺酰胺及其在癌症治疗中的应用公开(公告)号：US20100249099A1
公开(公告)日：2010-09-30
申请号：US12748251
申请日：2010-03-26
申请人： Gordon William Rewcastle , Swarnalatha Akuratiya Gamage , Jack Urquhart Flanagan , Anna Claire Giddens , Kit Yee Tsang
发明人： Gordon William Rewcastle , Swarnalatha Akuratiya Gamage , Jack Urquhart Flanagan , Anna Claire Giddens , Kit Yee Tsang
IPC分类号： A61K31/5377 , C07D413/14 , C12N9/12 , C07D487/04 , C07D491/08 , A61K31/55 , C07D417/14 , A61K31/541 , A61P35/00
CPC分类号： C07D491/08 , A61K31/5355 , A61K31/541 , A61K45/06 , C07D403/04 , C07D403/14 , C07D413/14 , C07D473/34 , C07D487/04 , C07D498/08
摘要： Provided herein are pyrimidinyl and 1,3,5-triazinyl benzimidazole sulfonamides, e.g., compounds of Formulae IA, IB, and IC, and their pharmaceutical compositions, preparation, and use as agents or drugs for cancer therapy, either alone or in combination with radiation and/or other anticancer drugs.
摘要翻译： 本文提供了嘧啶基和1,3,5-三嗪基苯并咪唑磺酰胺，例如式IA，IB和IC的化合物，以及它们的药物组合物，制备和用作癌症治疗的药物或药物，单独或与 辐射和/或其他抗癌药物。
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5.发明申请PYRIMIDINYL AND 1,3,5-TRIAZINYL BENZIMIDAZOLES AND THEIR USE IN CANCER THERAPY 有权吡嗪二酮和1,3,5-三嗪基苯并咪唑及其在癌症治疗中的应用公开(公告)号：US20110009405A1
公开(公告)日：2011-01-13
申请号：US12831128
申请日：2010-07-06
IPC分类号： A61K31/5377 , C07D413/14 , A61P35/00 , C12N9/12
CPC分类号： C07D487/04 , C07D401/14 , C07D403/04 , C07D403/14
摘要： Provided herein are pyrimidinyl and 1,3,5-triazinyl benzimidazoles of Formula I, and their pharmaceutical compositions, preparation, and use as agents or drugs for cancer therapy, either alone or in combination with radiation and/or other anticancer drugs.
摘要翻译： 本文提供式I的嘧啶基和1,3,5-三嗪基苯并咪唑及其药物组合物，制剂和用作癌症治疗的药物或药物，单独或与辐射和/或其它抗癌药物组合。
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