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![USE OF 7-CHLORO-N,N,5-TRIMETHYL-4-OXO-3-PHENYL-3,5-DIHYDRO-4H-PYRIDAZINO[4,5-B] INDOLE-1-ACETAMIDE AS A BIOMARKER OF PERIPHERAL BENZODIAZEPINE RECEPTOR LEVELS](/abs-image/US/2012/02/16/US20120039816A1/abs.jpg.150x150.jpg)
1.发明申请USE OF 7-CHLORO-N,N,5-TRIMETHYL-4-OXO-3-PHENYL-3,5-DIHYDRO-4H-PYRIDAZINO[4,5-B] INDOLE-1-ACETAMIDE AS A BIOMARKER OF PERIPHERAL BENZODIAZEPINE RECEPTOR LEVELS 审中-公开使用7-氯代-N，N，5-三甲基-4-氧代-3-苯基-3,5-二氢-4H-吡啶并[4,5-B]吲哚-1-乙酰胺作为外周苯并二氮杂受体的生物标志物 水平公开(公告)号：US20120039816A1
公开(公告)日：2012-02-16
申请号：US13126648
申请日：2009-10-27
申请人： Jesus Benavides , Hérve Boutin , Marie-Noëlle Castel , Annelaure Damont , Frédéric Dolle , Philippe Hantraye , Frank Marguet , Thomas Rooney , Luc Rivron , Bertrand Tavitian , Cyrille Thominiaux
发明人： Jesus Benavides , Hérve Boutin , Marie-Noëlle Castel , Annelaure Damont , Frédéric Dolle , Philippe Hantraye , Frank Marguet , Thomas Rooney , Luc Rivron , Bertrand Tavitian , Cyrille Thominiaux
IPC分类号： A61K49/04 , C07D487/04
CPC分类号： G01N33/6872 , A61K51/0459 , G01N33/58 , G01N2333/705
摘要： Use of a radiolabelled form of 7-chloro-Λ/,Λ/,5-trimethyl-4-oxo-3-phenyl-3,5-dihydro-4/-/-pyridazino[4,5-b]indole-1-acetamide as a biomarker for the detection, in an individual, of PBR levels associated with normal and pathological conditions. Method for the detection of PBR levels associated with normal and pathological conditions. Diagnostic kit.
摘要翻译： 使用放射性标记形式的7-氯代Λ/，Λ/，5-三甲基-4-氧代-3-苯基-3,5-二氢-4H-哒嗪并[4,5-b]吲哚-1 - 乙酰胺作为用于在个体中检测与正常和病理状况相关的PBR水平的生物标志物。 检测与正常和病理状况相关的PBR水平的方法。 诊断套件
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