公开(公告)号：US06290973B1

公开(公告)日：2001-09-18

申请号：US09496152

申请日：2000-02-01

申请人： Lynn D. Hawkins ,  Sally T. Ishizaka ,  Michael Lewis ,  Pamela McGuiness ,  Anneliese Nault ,  Jeffrey Rose ,  Daniel P. Rossignol

发明人： Lynn D. Hawkins ,  Sally T. Ishizaka ,  Michael Lewis ,  Pamela McGuiness ,  Anneliese Nault ,  Jeffrey Rose ,  Daniel P. Rossignol

IPC分类号： A61K4500

CPC分类号： C07F9/65515 ,  A61K39/39 ,  A61K2039/55511 ,  A61K2039/55555 ,  C07F9/091 ,  C07F9/10

摘要： The present invention is directed to novel compounds that function as immunological adjuvants when co-administered with antigens such as vaccines for bacterial and viral diseases, to novel adjuvant formulations which include at least one of the adjuvant compounds of the invention, to novel immunostimulatory compositions which comprise an antigen and at least one of the adjuvant compounds of the invention, and to methods for the immunization of an animal by co-administration of a compound of the invention with an antigen against which the animal is to be immunized.

摘要翻译： 本发明涉及当与诸如用于细菌和病毒疾病的疫苗的抗原共同给予包括至少一种本发明的佐剂化合物的新型佐剂制剂与新的免疫刺激组合物共同施用时用作免疫佐剂的新化合物， 包括抗原和至少一种本发明的佐剂化合物，以及通过将本发明化合物与待免疫动物的抗原共同给药的动物免疫方法。