TRANSDERMAL THERAPEUTIC SYSTEM WITH TWO-PHASE RELEASE PROFILE
    1.
    发明申请
    TRANSDERMAL THERAPEUTIC SYSTEM WITH TWO-PHASE RELEASE PROFILE 审中-公开
    具有两相释放特性的超导治疗系统

    公开(公告)号:US20100143475A1

    公开(公告)日:2010-06-10

    申请号:US12311305

    申请日:2007-08-27

    CPC分类号: A61K9/7061 A61K31/48

    摘要: The present invention relates to a transdermal therapeutic system (TTS) consisting of an impermeable coating, a matrix containing an ergoline compound having the formula (I) or a physiologically compatible salt or derivative thereof, wherein R1 denotes an H atom or a halogen atom and R2 is an alkyl group having 1 to 4 carbon atoms and denotes a single or double bond, and a removable protective layer, wherein the ergoline compound or a physiologically compatible salt or derivative thereof is stabilised by an antioxidant and a basic polymer. The TTS is characterised in that the matrix contains at least one hydrocarbon having 8 to 18 carbon atoms in a straight or branched chain, which has a functional group at the end of the alkyl chain and/or Aloe Vera, so that in a first phase (0-5 hours after application) only 0-20% of the therapeutically desired steady-state plasma concentration of the ergoline compound is achieved and the therapeutically desired steady-state plasma concentration of the ergoline compound is only achieved in a second phase (5-20 hours after application).

    摘要翻译: 本发明涉及一种由不透水涂层组成的透皮治疗系统(TTS),含有式(I)的麦角灵化合物或其生理上相容的盐或衍生物的基质,其中R1表示H原子或卤素原子, R2是具有1至4个碳原子并且表示单键或双键的烷基和可除去的保护层,其中麦角灵化合物或其生理上相容的盐或其衍生物由抗氧化剂和碱性聚合物稳定。 TTS的特征在于,基质含有至少一个在直链或支链上具有8至18个碳原子的烃,其在烷基链和/或芦荟末端具有官能团,因此在第一相中 (施用后0-5小时)仅实现治疗期望的稳态血浆浓度的0〜20%的麦角灵化合物,并且仅在第二阶段(5)中实现麦角灵化合物的治疗期望的稳态血浆浓度 应用后-20小时)。

    SENSOR ARRANGEMENT FOR DETECTING AMBIENT CONDITIONS
    2.
    发明申请
    SENSOR ARRANGEMENT FOR DETECTING AMBIENT CONDITIONS 有权
    用于检测环境条件的传感器布置

    公开(公告)号:US20120006110A1

    公开(公告)日:2012-01-12

    申请号:US13178343

    申请日:2011-07-07

    IPC分类号: G01W1/14 G01K1/00 H01J40/00

    摘要: The invention relates to a sensor arrangement for detecting ambient conditions, in particular for a motor vehicle, with at least one carrier plate and optical elements arranged on this carrier plate, wherein several of the optical elements are arranged around a shared central region on the carrier plate, and at least two of the optical elements arranged around the central region exhibit primary action axes. These primary action axes are adjusted at a predetermined angle relative to the carrier plate, wherein the primary action axes are directed toward the shared central region. Additional sensors arranged on the carrier plate include a rain sensor, a solar sensor as well as various light sensors, which preferably are arranged on receiving surfaces of the carrier plate.

    摘要翻译: 本发明涉及一种用于检测特别是机动车辆的环境条件的传感器装置,其中至少一个载板和布置在该承载板上的光学元件,其中几个光学元件围绕载体上的共享中心区域布置 并且围绕中心区域布置的至少两个光学元件表现出主要作用轴。 这些主作用轴相对于承载板以预定角度被调节,其中主动作轴线指向共享中心区域。 布置在承载板上的附加传感器包括雨传感器,太阳能传感器以及各种光传感器,其优选地布置在承载板的接收表面上。

    Sensor arrangement for detecting ambient conditions
    3.
    发明授权
    Sensor arrangement for detecting ambient conditions 有权
    用于检测环境条件的传感器布置

    公开(公告)号:US08434359B2

    公开(公告)日:2013-05-07

    申请号:US13178343

    申请日:2011-07-07

    IPC分类号: G01W1/14 G01K1/00

    摘要: The invention relates to a sensor arrangement for detecting ambient conditions, in particular for a motor vehicle, with at least one carrier plate and optical elements arranged on this carrier plate, wherein several of the optical elements are arranged around a shared central region on the carrier plate, and at least two of the optical elements arranged around the central region exhibit primary action axes. These primary action axes are adjusted at a predetermined angle relative to the carrier plate, wherein the primary action axes are directed toward the shared central region. Additional sensors arranged on the carrier plate include a rain sensor, a solar sensor as well as various light sensors, which preferably are arranged on receiving surfaces of the carrier plate.

    摘要翻译: 本发明涉及一种用于检测特别是机动车辆的环境条件的传感器装置,其中至少一个载板和布置在该承载板上的光学元件,其中几个光学元件围绕载体上的共享中心区域布置 并且围绕中心区域布置的至少两个光学元件表现出主要作用轴。 这些主作用轴相对于承载板以预定角度被调节,其中主动作轴线指向共享中心区域。 布置在承载板上的附加传感器包括雨传感器,太阳能传感器以及各种光传感器,其优选地布置在承载板的接收表面上。

    METHOD AND SENSOR ARRANGEMENT FOR DETECTING THE VISIBILITY OUTSIDE OF A MOTOR VEHICLE
    4.
    发明申请
    METHOD AND SENSOR ARRANGEMENT FOR DETECTING THE VISIBILITY OUTSIDE OF A MOTOR VEHICLE 审中-公开
    用于检测电动车外部可视性的方法和传感器装置

    公开(公告)号:US20120007507A1

    公开(公告)日:2012-01-12

    申请号:US13172523

    申请日:2011-06-29

    IPC分类号: B60Q1/02

    CPC分类号: G01D21/02

    摘要: The invention relates to a method for detecting the visibility outside of a motor vehicle by means of at least two light sensors, in the case of which the intensity of the light reflection of the driving light emitted in the direction of travel is detected by means of a first light sensor, which is oriented in the direction of travel. The first light sensor thereby transmits at least a first evaluation signal to a control unit for further processing at least as a function of the recorded intensity of the light reflection. The ambient light is detected by means of a second light sensor and a second evaluation signal is transmitted to the control unit as a function of the intensity of the ambient light. The control unit correlates the evaluation signals of both light sensors and the light intensity threshold value is determined on the basis thereof. The control unit outputs different control signals in each case, in response the first evaluation signal is exceeding of falling below of the determined light intensity threshold value.

    摘要翻译: 本发明涉及一种用于通过至少两个光传感器来检测机动车外部的可见度的方法,在这种情况下,通过以下方式检测在行驶方向上发射的驱动光的光反射强度: 第一光传感器,其沿行进方向定向。 因此,第一光传感器至少将至少第一评估信号发送到控制单元,用于至少根据记录的光反射强度的函数进一步处理。 通过第二光传感器检测环境光,并且第二评估信号作为环境光强度的函数传输到控制单元。 控制单元将两个光传感器的评估信号相关联,并且基于此确定光强度阈值。 响应于第一评估信号超过确定的光强度阈值以下,控制单元在每种情况下输出不同的控制信号。

    SENSOR ARRANGEMENT FOR ACQUIRING STATE VARIABLES
    5.
    发明申请
    SENSOR ARRANGEMENT FOR ACQUIRING STATE VARIABLES 审中-公开
    用于获取状态变量的传感器布置

    公开(公告)号:US20120006907A1

    公开(公告)日:2012-01-12

    申请号:US13177211

    申请日:2011-07-06

    IPC分类号: G05D22/02 G01N19/10

    摘要: The invention relates to a device for acquiring predetermined state variables inside a room, in particular in the interior of a motor vehicle, with at least one temperature sensor and with a humidity sensor, at least regions of which are enclosed by a housing, wherein a first temperature sensor exhibits at least one contact surface for abutting against a perimeter surface bordering the room, and that at least one second temperature sensor is provided inside the housing for acquiring the room temperature. The contact surface is thereby a surface piece of a printed circuit board section of a printed circuit board, which encompasses elastic characteristics, wherein the printed circuit board section encompasses a plurality of surface pieces, which are angled relative to one another, and the temperature sensors are arranged at different surface pieces.

    摘要翻译: 本发明涉及一种用于通过至少一个温度传感器和一个湿度传感器在房间内特别是在机动车辆的内部获取预定状态变量的装置,至少一个区域被壳体包围, 第一温度传感器具有至少一个接触表面,用于邻接与房间邻接的周边表面,并且至少一个第二温度传感器设置在壳体内用于获取室温。 因此,接触表面是印刷电路板的印刷电路板部分的表面片,其包含弹性特性,其中印刷电路板部分包围相对于彼此成角度的多个表面片,并且温度传感器 布置在不同的表面片上。