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公开(公告)号:US20170022199A1
公开(公告)日:2017-01-26
申请号:US15285614
申请日:2016-10-05
申请人: Nigel Graham COOKE , Antonio Paulo Fernandes Gomes Dos Santos , Nadege GRAVELEAU , Christina HEBACH , Klemens HOEGENAUER , Gregory John HOLLINGWORTH , Alexander Baxter SMITH , Nicolaus SOLDERMANN , Frank STOWASSER , Ross Sinclair STRANG , Nicola TUFILLI , Anette von MATT , Romain WOLF , Frederic ZECRI
发明人: Nigel Graham COOKE , Antonio Paulo Fernandes Gomes Dos Santos , Nadege GRAVELEAU , Christina HEBACH , Klemens HOEGENAUER , Gregory John HOLLINGWORTH , Alexander Baxter SMITH , Nicolaus SOLDERMANN , Frank STOWASSER , Ross Sinclair STRANG , Nicola TUFILLI , Anette von MATT , Romain WOLF , Frederic ZECRI
IPC分类号: C07D471/04 , A61K31/5377 , A61K31/519
CPC分类号: C07D471/04 , A61K31/519 , A61K31/5377 , C07B2200/05
摘要: The invention relates to substituted tetrahydro-pyrido-pyrimidine derivatives of the formula (I), wherein Y, R1, R2 and m are as defined in the description. Such compounds are suitable for the treatment of a disorder or disease which is mediated by the activity of the PI3K enzymes.
摘要翻译: 其中Y,R 1,R 2和m如说明书中所定义。 这些化合物适用于治疗由PI3K酶的活性介导的病症或疾病。