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公开(公告)号:US20110300205A1
公开(公告)日:2011-12-08
申请号:US12831252
申请日:2010-07-06
申请人: Andrew Geall , Armin Hekele , Christian Mandl
发明人: Andrew Geall , Armin Hekele , Christian Mandl
IPC分类号: A61K9/127 , C12N5/071 , A61K9/14 , A61P37/04 , A61K39/00 , A61K31/7088 , A61K48/00 , A61P31/00 , C07H21/02 , A61K9/50
CPC分类号: A61K39/00 , A61K2039/53 , A61K2039/55555 , C12N15/113 , C12N15/86 , C12N2310/123 , C12N2770/36143
摘要: This application discloses self-replicating RNA molecules that contain modified nucleotides, compositions that contain the self-replicating RNA molecules, and methods for using the self-replicating RNA molecules, for example, to raise an immune response.
摘要翻译: 本申请公开了含有修饰的核苷酸的自我复制的RNA分子,含有自我复制的RNA分子的组合物,以及使用自我复制的RNA分子的方法,例如提高免疫应答。