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1.发明授权Process analysis system with sterile sampling of mechanically-sensitive material from a bioreactor 有权具有来自生物反应器的机械敏感材料的无菌取样的工艺分析系统公开(公告)号：US08431089B2
公开(公告)日：2013-04-30
申请号：US12297831
申请日：2007-04-17
申请人： Stefan Steigmiller , Hans Tups , Karsten Sommer , Sonja Danstedt , Martin Schiffhauer , Sebastian Schmidt , Jörg Kauling , Arndt Braun
发明人： Stefan Steigmiller , Hans Tups , Karsten Sommer , Sonja Danstedt , Martin Schiffhauer , Sebastian Schmidt , Jörg Kauling , Arndt Braun
IPC分类号： B01L3/00
CPC分类号： G01N1/10 , C12M33/04 , C12M37/02 , G01N1/2035
摘要： Sampling valve with which samples containing mechanically sensitive material are removed in a sterile manner from a bioreactor, and process analysis system with analysis stations, in particular chromatography systems, biosensors and cell determination devices, permitting automated, sterile removal of a sample from a bioreactor and gentle transport of the sample, containing mechanically sensitive material, in particular cells, to the analysis station.
摘要翻译： 使用来自生物反应器的以无菌方式除去机械敏感材料的样品的采样阀，以及具有分析站，特别是色谱系统，生物传感器和细胞测定装置的工艺分析系统，允许从生物反应器自动无菌除去样品， 样品的温和运输，将机械敏感材料（特别是细胞）包含在分析台中。
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公开(公告)号：US20120100605A1
公开(公告)日：2012-04-26
申请号：US13318660
申请日：2009-12-03
CPC分类号： B01J19/285 , B01F11/0002 , B01F15/00876 , C12M23/26 , C12M27/10 , G06K19/0716
摘要： A reactor is designed as a disposable element, a container receives the reactor, and a device comprises a reactor. A drive unit of the device generates a rotating-oscillating motion of the reactor, and the device is utilized for cultivating cells and/or microorganisms.
摘要翻译： 反应器设计为一次性元件，容器接收反应器，并且装置包括反应器。 该装置的驱动单元产生反应器的旋转振荡运动，并且该装置用于培养细胞和/或微生物。
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公开(公告)号：US20110097800A1
公开(公告)日：2011-04-28
申请号：US12997281
申请日：2009-06-10
申请人： Joerg Kauling , Björn Frahm , Marc Jenne , Helmut Brod , Stephan Kirchner , Arndt Braun
发明人： Joerg Kauling , Björn Frahm , Marc Jenne , Helmut Brod , Stephan Kirchner , Arndt Braun
摘要： The invention relates to a device and a method for retaining and recirculating cells in a vessel through which flow passes continuously or batchwise.In addition, the invention relates to a method of producing a device by which cells can be retained and recirculated in a vessel through which flow passes continuously or batchwise.
摘要翻译： 本发明涉及一种用于保持和再循环在容器中的细胞的装置和方法，血液通过该细胞连续或间歇地流过。 此外，本发明涉及一种生产装置的方法，通过该装置可以将细胞保持和再循环在流过连续或间歇流过的容器中。
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4.发明申请PROCESS ANALYSIS SYSTEM WITH STERILE SAMPLING OF MECHANICALLY-SENSITIVE MATERIAL FROM A BIOREACTOR 有权过程分析系统，从生物反应器中无机取样机械敏感材料公开(公告)号：US20090178495A1
公开(公告)日：2009-07-16
申请号：US12297831
申请日：2007-04-17
申请人： Stefan Steigmiller , Hans Tups , Karsten Sommer , Sonja Danstedt , Martin Schiffhauer , Sebastian Schmidt , Jörg Kauling , Arndt Braun
发明人： Stefan Steigmiller , Hans Tups , Karsten Sommer , Sonja Danstedt , Martin Schiffhauer , Sebastian Schmidt , Jörg Kauling , Arndt Braun
IPC分类号： G01N30/20
CPC分类号： G01N1/10 , C12M33/04 , C12M37/02 , G01N1/2035
摘要： Sampling valve with which samples containing mechanically sensitive material are removed in a sterile manner from a bioreactor, and process analysis system with analysis stations, in particular chromatography systems, biosensors and cell determination devices, permitting automated, sterile removal of a sample from a bioreactor and gentle transport of the sample, containing mechanically sensitive material, in particular cells, to the analysis station
摘要翻译： 使用来自生物反应器的以无菌方式除去机械敏感材料的样品的采样阀，以及具有分析站，特别是色谱系统，生物传感器和细胞测定装置的工艺分析系统，允许从生物反应器自动无菌除去样品， 样品的温和运输，将机械敏感材料（特别是细胞）包含在分析台中
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