公开(公告)号：US20090178495A1

公开(公告)日：2009-07-16

申请号：US12297831

申请日：2007-04-17

申请人： Stefan Steigmiller ,  Hans Tups ,  Karsten Sommer ,  Sonja Danstedt ,  Martin Schiffhauer ,  Sebastian Schmidt ,  Jörg Kauling ,  Arndt Braun

发明人： Stefan Steigmiller ,  Hans Tups ,  Karsten Sommer ,  Sonja Danstedt ,  Martin Schiffhauer ,  Sebastian Schmidt ,  Jörg Kauling ,  Arndt Braun

IPC分类号： G01N30/20

CPC分类号： G01N1/10 ,  C12M33/04 ,  C12M37/02 ,  G01N1/2035

摘要： Sampling valve with which samples containing mechanically sensitive material are removed in a sterile manner from a bioreactor, and process analysis system with analysis stations, in particular chromatography systems, biosensors and cell determination devices, permitting automated, sterile removal of a sample from a bioreactor and gentle transport of the sample, containing mechanically sensitive material, in particular cells, to the analysis station

摘要翻译： 使用来自生物反应器的以无菌方式除去机械敏感材料的样品的采样阀，以及具有分析站，特别是色谱系统，生物传感器和细胞测定装置的工艺分析系统，允许从生物反应器自动无菌除去样品， 样品的温和运输，将机械敏感材料（特别是细胞）包含在分析台中

公开(公告)号：US08431089B2

公开(公告)日：2013-04-30

申请号：US12297831

申请日：2007-04-17

申请人： Stefan Steigmiller ,  Hans Tups ,  Karsten Sommer ,  Sonja Danstedt ,  Martin Schiffhauer ,  Sebastian Schmidt ,  Jörg Kauling ,  Arndt Braun

发明人： Stefan Steigmiller ,  Hans Tups ,  Karsten Sommer ,  Sonja Danstedt ,  Martin Schiffhauer ,  Sebastian Schmidt ,  Jörg Kauling ,  Arndt Braun

IPC分类号： B01L3/00

CPC分类号： G01N1/10 ,  C12M33/04 ,  C12M37/02 ,  G01N1/2035

摘要： Sampling valve with which samples containing mechanically sensitive material are removed in a sterile manner from a bioreactor, and process analysis system with analysis stations, in particular chromatography systems, biosensors and cell determination devices, permitting automated, sterile removal of a sample from a bioreactor and gentle transport of the sample, containing mechanically sensitive material, in particular cells, to the analysis station.

摘要翻译： 使用来自生物反应器的以无菌方式除去机械敏感材料的样品的采样阀，以及具有分析站，特别是色谱系统，生物传感器和细胞测定装置的工艺分析系统，允许从生物反应器自动无菌除去样品， 样品的温和运输，将机械敏感材料（特别是细胞）包含在分析台中。

公开(公告)号：US20130086981A1

公开(公告)日：2013-04-11

申请号：US13611488

申请日：2012-09-12

申请人： Stefan Steigmiller ,  Karsten Sommer ,  Christoph Knappe

发明人： Stefan Steigmiller ,  Karsten Sommer ,  Christoph Knappe

IPC分类号： G01N1/40 ,  B01D29/56

CPC分类号： G01N1/40 ,  B01D29/09 ,  B01D29/56 ,  G01N15/0272 ,  G01N35/00009 ,  G01N2001/4088

摘要： The invention provides an apparatus for discontinuous filtration of a liquid, having a filter station for filtration, a feed line for supplying the liquid to the filter station, and a filter medium movable relative to the station, the filter medium comprising at least two different membranes, which together in the filter station effect multistage filtration. The invention additionally relates to a method for discontinuous filtration of a liquid or for filtering isolated quantities of liquid, comprising: providing a filter station for filtration, the filter station comprising a chamber in which filtration is carried out; moving or transporting a filter medium from a stock into the filter station, the filter medium comprising at least two membranes which are arranged next to one another in the chamber; and supplying the liquid to the chamber, such that the liquid is subjected to multistage filtration through the membranes.

摘要翻译： 本发明提供了一种用于不连续过滤液体的装置，具有用于过滤的过滤站，用于将液体供应到过滤站的进料管线和可相对于该工作站移动的过滤介质，所述过滤介质包括至少两个不同的膜 一起在过滤站中进行多级过滤。 本发明还涉及用于不连续过滤液体或用于过滤隔离液体的方法，其包括：提供用于过滤的过滤站，所述过滤站包括进行过滤的室; 将过滤介质从原料移动或输送到过滤站中，所述过滤介质包括在所述室中彼此相邻布置的至少两个膜; 并将液体供应到室中，使得液体经由膜进行多级过滤。