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公开(公告)号：US20090306346A1
公开(公告)日：2009-12-10
申请号：US12095784
申请日：2006-12-15
IPC分类号： C07K1/18
CPC分类号： C07K1/16 , B01D15/361 , B01J20/12 , B01J20/28057 , B01J20/28069 , B01J20/282
摘要： The invention relates to a method for separating proteins from liquid media, comprising providing a liquid medium containing proteins, providing a clay material which has: a specific surface greater than 150 m2/g, a pore volume greater than 0.35 ml/g, an ion exchange capacity greater than 40 meq/100 g, and a sediment volume in water of less than 15 ml/2 g, equilibrating said clay material to a pH of from 3.5 to 9.0, treating said liquid medium with the equilibrated clay material, and separating the purified, protein-depleted liquid medium from the clay material.
摘要翻译： 本发明涉及一种从液体培养基中分离蛋白质的方法，包括提供含有蛋白质的液体培养基，提供粘土材料，其具有大于150m 2 / g的比表面积，大于0.35ml / g的孔体积，离子 交换容量大于40meq / 100g，水中的沉淀物体积小于15ml / 2g，将所述粘土材料平衡至3.5至9.0的pH，用平衡的粘土材料处理所述液体介质，并分离 从粘土材料中纯化的，蛋白质贫乏的液体培养基。
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公开(公告)号：US07897051B2
公开(公告)日：2011-03-01
申请号：US12095784
申请日：2006-12-15
IPC分类号： B01D15/04
CPC分类号： C07K1/16 , B01D15/361 , B01J20/12 , B01J20/28057 , B01J20/28069 , B01J20/282
摘要： The invention relates to a method for separating proteins from liquid media, comprising providing a liquid medium containing proteins, providing a clay material which has: a specific surface greater than 150 m2/g, a pore volume greater than 0.35 ml/g, an ion exchange capacity greater than 40 meq/100 g, and a sediment volume in water of less than 15 ml/2 g, equilibrating said clay material to a pH of from 3.5 to 9.0, treating said liquid medium with the equilibrated clay material, and separating the purified, protein-depleted liquid medium from the clay material.
摘要翻译： 本发明涉及一种从液体培养基中分离蛋白质的方法，包括提供含有蛋白质的液体培养基，提供粘土材料，其具有大于150m 2 / g的比表面积，大于0.35ml / g的孔体积，离子 交换容量大于40meq / 100g，水中的沉淀物体积小于15ml / 2g，将所述粘土材料平衡至3.5至9.0的pH，用平衡的粘土材料处理所述液体介质，并分离 从粘土材料中纯化的，蛋白质贫乏的液体培养基。
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