-
公开(公告)号：US20090306346A1
公开(公告)日：2009-12-10
申请号：US12095784
申请日：2006-12-15
IPC分类号： C07K1/18
CPC分类号： C07K1/16 , B01D15/361 , B01J20/12 , B01J20/28057 , B01J20/28069 , B01J20/282
摘要： The invention relates to a method for separating proteins from liquid media, comprising providing a liquid medium containing proteins, providing a clay material which has: a specific surface greater than 150 m2/g, a pore volume greater than 0.35 ml/g, an ion exchange capacity greater than 40 meq/100 g, and a sediment volume in water of less than 15 ml/2 g, equilibrating said clay material to a pH of from 3.5 to 9.0, treating said liquid medium with the equilibrated clay material, and separating the purified, protein-depleted liquid medium from the clay material.
摘要翻译： 本发明涉及一种从液体培养基中分离蛋白质的方法，包括提供含有蛋白质的液体培养基，提供粘土材料，其具有大于150m 2 / g的比表面积，大于0.35ml / g的孔体积，离子 交换容量大于40meq / 100g，水中的沉淀物体积小于15ml / 2g，将所述粘土材料平衡至3.5至9.0的pH，用平衡的粘土材料处理所述液体介质，并分离 从粘土材料中纯化的，蛋白质贫乏的液体培养基。
-
公开(公告)号：US07897051B2
公开(公告)日：2011-03-01
申请号：US12095784
申请日：2006-12-15
IPC分类号： B01D15/04
CPC分类号： C07K1/16 , B01D15/361 , B01J20/12 , B01J20/28057 , B01J20/28069 , B01J20/282
摘要： The invention relates to a method for separating proteins from liquid media, comprising providing a liquid medium containing proteins, providing a clay material which has: a specific surface greater than 150 m2/g, a pore volume greater than 0.35 ml/g, an ion exchange capacity greater than 40 meq/100 g, and a sediment volume in water of less than 15 ml/2 g, equilibrating said clay material to a pH of from 3.5 to 9.0, treating said liquid medium with the equilibrated clay material, and separating the purified, protein-depleted liquid medium from the clay material.
摘要翻译： 本发明涉及一种从液体培养基中分离蛋白质的方法，包括提供含有蛋白质的液体培养基，提供粘土材料，其具有大于150m 2 / g的比表面积，大于0.35ml / g的孔体积，离子 交换容量大于40meq / 100g，水中的沉淀物体积小于15ml / 2g，将所述粘土材料平衡至3.5至9.0的pH，用平衡的粘土材料处理所述液体介质，并分离 从粘土材料中纯化的，蛋白质贫乏的液体培养基。
-
3.发明申请METHOD FOR THE SORPTION OF AT LEAST ONE NUCLEIC ACID-ACTIVATED PHYLLOSILICATES 审中-公开用于最少一个核酸活化的木质素的分离方法公开(公告)号：US20090221809A1
公开(公告)日：2009-09-03
申请号：US12096402
申请日：2005-12-09
CPC分类号： B01J20/12 , B01D15/08 , B01D15/362 , B01D15/424 , B01J20/10 , B01J20/28004 , B01J20/28016 , B01J20/2803 , B01J20/28033 , B01J20/28057 , B01J20/28069 , B01J20/28078
摘要： The invention relates to a method for the sorption of at least one nucleic acid molecule from a liquid medium, comprising the following steps: (a) providing a liquid medium comprising at least one nucleic acid molecule; (b) providing a layer comprising at least one acid-activated phyllosilicate, where the layer is permeable by the liquid medium, and the layer thickness is at least 1 mm; (c) passing the liquid medium with the at least one nucleic acid molecule from step (a) through the layer from step (b) for sorption of the at least one nucleic acid molecule in the layer.
摘要翻译： 本发明涉及一种从液体培养基中吸附至少一种核酸分子的方法，包括以下步骤：（a）提供包含至少一种核酸分子的液体培养基; （b）提供包含至少一种酸活化的页硅酸盐的层，其中所述层可被液体介质渗透，并且层厚度为至少1mm; （c）将来自步骤（a）的至少一种核酸分子的液体培养基通过来自步骤（b）的层，用于吸收该层中的至少一个核酸分子。
-
公开(公告)号：US20090075362A1
公开(公告)日：2009-03-19
申请号：US12226463
申请日：2007-04-24
申请人： Reinhard Baumfalk , Oscar-Werner Reif , Thomas Scheper , Daniel Riechers , Russell Hayden , Philip Nuzzo
发明人： Reinhard Baumfalk , Oscar-Werner Reif , Thomas Scheper , Daniel Riechers , Russell Hayden , Philip Nuzzo
IPC分类号： C12M3/00
CPC分类号： C12M23/28 , B01L3/505 , B01L2200/026 , B01L2200/04 , B01L2300/0627 , B01L2300/0645 , B01L2300/0654 , C12M23/00 , C12M23/14 , C12M41/00
摘要： The invention relates to a disposable bioreactor comprising a reversible, externally attachable sensor arrangement for measuring a physical variable of a contained medium. A sensor adapter (28) for receiving an electronic sensor arrangement (34, 38; 42; 44a, 44b, 46, 48) interacting with the medium cross-flowing the peripheral lines (14, 16, 18), by means of an inner delimiting surface (32a, 32b; 42; 44a, 44b, 46, 48) of the sensor adapter, is integrated into at least one of the peripheral lines (14, 16, 18) of the bioreactor which is used to supply or discharge the medium. Said sensor adapter (28) is mounted on the peripheral line (14, 16, 18) as an insert extending the peripheral line (14, 16, 18) and which can be cross-flown by the contained medium.
摘要翻译： 本发明涉及一种一次性生物反应器，其包括用于测量所容纳介质的物理变量的可逆的外部可附接的传感器装置。 一种传感器适配器（28），用于接收与所述介质相互作用的电子传感器装置（34,38; 42; 44a，44b，46,48），所述电子传感器装置通过内部 所述传感器适配器的限定表面（32a，32b; 42; 44a，44b，46,48）被整合到所述生物反应器的至少一个外围线路（14,16,18）中，所述外围线路用于提供或释放 中。 所述传感器适配器（28）作为插入件延伸外围线路（14,16,18）而安装在外围线路（14,16,18）上，并可由所容纳的介质交叉流动。
-
公开(公告)号：US08252582B2
公开(公告)日：2012-08-28
申请号：US12226463
申请日：2007-04-24
申请人： Reinhard Baumfalk , Oscar-Werner Reif , Thomas Scheper , Daniel Riechers , Russell Hayden , Philip Nuzzo
发明人： Reinhard Baumfalk , Oscar-Werner Reif , Thomas Scheper , Daniel Riechers , Russell Hayden , Philip Nuzzo
CPC分类号： C12M23/28 , B01L3/505 , B01L2200/026 , B01L2200/04 , B01L2300/0627 , B01L2300/0645 , B01L2300/0654 , C12M23/00 , C12M23/14 , C12M41/00
摘要： The invention relates to a disposable bioreactor comprising a reversible, externally attachable sensor arrangement for measuring a physical variable of a contained medium. A sensor adapter (28) for receiving an electronic sensor arrangement (34, 38; 42; 44a, 44b, 46, 48) interacting with the medium cross-flowing the peripheral lines (14, 16, 18), by means of an inner delimiting surface (32a, 32b; 42; 44a, 44b, 46, 48) of the sensor adapter, is integrated into at least one of the peripheral lines (14, 16, 18) of the bioreactor which is used to supply or discharge the medium. Said sensor adapter (28) is mounted on the peripheral line (14, 16, 18) as an insert extending the peripheral line (14, 16, 18) and which can be cross-flown by the contained medium.
摘要翻译： 本发明涉及一种一次性生物反应器，其包括用于测量所容纳介质的物理变量的可逆的外部可附接的传感器装置。 一种传感器适配器（28），用于接收与所述介质相互作用的电子传感器装置（34,38; 42; 44a，44b，46,48），所述电子传感器装置通过内部 所述传感器适配器的限定表面（32a，32b; 42; 44a，44b，46,48）被整合到所述生物反应器的至少一个外围线路（14,16,18）中，所述外围线路用于供应或排出 中。 所述传感器适配器（28）作为插入件延伸外围线路（14,16,18）而安装在外围线路（14,16,18）上，并可由所容纳的介质交叉流动。
-
公开(公告)号：US20100035337A1
公开(公告)日：2010-02-11
申请号：US12460314
申请日：2009-07-16
IPC分类号： C12M3/00
摘要： Bioreactor having at least one transparent window (5, 12, 13), the inner side (6) of which can be touched by a medium that can be arranged in a reactor interior (3), wherein the window (5, 12, 13) has a photocatalytic coating (7) on its inner side (6) facing the reactor interior (3), which coating can be activated by at least one light source from the outer side remote from the inner side (6).
摘要翻译： 生物反应器具有至少一个透明窗口（5,12,13），其内侧（6）可以被可布置在反应器内部（3）中的介质所接触，其中窗口（5,12,13） ）在其内侧（6）上具有面向反应器内部（3）的光催化涂层（7），该涂层可以由远离内侧（6）的外侧的至少一个光源激活。
-
公开(公告)号：US09809793B2
公开(公告)日：2017-11-07
申请号：US13521230
申请日：2011-01-18
申请人： Daniel Riechers
发明人： Daniel Riechers
摘要： A bioreactor vessel has an optical foam sensor (36) with a foam contact surface for contacting the foam to be detected. The foam contact surface is an inner side of a window (38) transparent to light from the visible and ultraviolet spectral range in an outer wall of the bioreactor vessel (10). An outer side of the window (38) is coupled to an illumination and detection unit (52) with at least one first light source (56) of visible light and at least one photodetector (58) to detect light from the first light source (56) that is reflected in the bioreactor vessel (10). The foam contact surface has a titanium dioxide coating (44) superhydrophilizable by photoactivation with ultraviolet light and the illumination and detection unit (52) has at least one second light source (66) of ultraviolet light.
-
8.发明申请OPTICAL SENSOR COMPRISING A LAYER SOLUBLE IN THE MEDIUM TO BE MEASURED AND DEVICE COMPRISING IT, AND PROCESS FOR THEIR PRODUCTION 有权包含要测量的介质中的层可溶性的光学传感器及其包含的设备及其生产过程公开(公告)号：US20120132813A1
公开(公告)日：2012-05-31
申请号：US13389151
申请日：2010-07-10
CPC分类号： G01N21/645
摘要： An optical is provided with reduced sensitivity to radiation, more particularly gamma radiation. The optical sensor is suitable for determining at least one parameter in a medium and includes a matrix containing a fluorescent dye. The matrix is supported by a transparent support. On the side facing the medium, the matrix has a layer soluble in the medium, which layer provides protection against radiation or damaging radiation products. The optical sensor is suitable for implementation in containers and laboratory products, such as disposable bioreactors for example, which are sterilized using gamma radiation.
摘要翻译： 提供对辐射的敏感性降低，特别是γ辐射的光学。 光学传感器适用于确定介质中的至少一个参数，并且包括含有荧光染料的基质。 矩阵由透明支持支持。 在面向介质的一侧，基质具有可溶于介质的层，该层可以防止辐射或损害辐射产物。 光学传感器适用于容器和实验室产品，例如使用γ辐射灭菌的一次性生物反应器。
-
9.发明申请SENSOR DEVICE, COMPRISING AN OPTICAL SENSOR, A CONTAINER AND A COMPARTMENTALIZATION MEANS 有权包含光学传感器，集装箱和货物装置的传感器装置公开(公告)号：US20120091326A1
公开(公告)日：2012-04-19
申请号：US13377845
申请日：2010-05-22
申请人： Reinhard Baumfalk , Stefan Weisshaar , Gerhard Greller , Daniel Riechers , Julia Lueders , Peter Pollossek
发明人： Reinhard Baumfalk , Stefan Weisshaar , Gerhard Greller , Daniel Riechers , Julia Lueders , Peter Pollossek
IPC分类号： H01J5/02
CPC分类号： A61L2/28 , A61L2/081 , G01N21/80 , G01N21/90 , G01N2021/7786
摘要： A sensor device has an optical sensor (1), a container (2) and a compartmentalizer (3) that temporarily divides the container into a main space (4) and an adjacent space (5), in which the optical sensor (1) is located. The gas volume in the direct vicinity of the optical sensor (1) is reduced, as are also, consequently, the reactive products generated by radiation sterilization. The adjacent space (5) can be united with the main space (4) after the sterilization as a result of the temporary compartmentalization. The optical sensor is suitable for implementation in containers and laboratory products, such as, for example, disposable bioreactors, that are sterilized by gamma radiation.
摘要翻译： 传感器装置具有光学传感器（1），容器（2）和分隔器（3），其将容器暂时分为主空间（4）和相邻的空间（5），其中光传感器（1） 位于。 直接靠近光学传感器（1）的气体体积减少，因此减少由辐射灭菌产生的反应性产物。 由于临时分隔，相邻的空间（5）可以在灭菌之后与主空间（4）结合。 光学传感器适用于容器和实验室产品，例如通过γ辐射灭菌的一次性生物反应器。
-
公开(公告)号：US20110198255A1
公开(公告)日：2011-08-18
申请号：US13123912
申请日：2009-10-06
CPC分类号： A61J1/10 , A61J1/14 , A61J2200/72 , A61J2205/20 , A61J2205/60 , A61J2205/70 , B01L3/52 , B01L3/545 , B01L2200/143 , B01L2200/148 , B01L2300/022 , B01L2300/023 , B01L2300/024 , B01L2300/027 , G01N33/48785 , G01N35/00732 , G01N35/1002 , G01N2035/00633 , G01N2035/00673 , G01N2035/00851 , Y10T29/49826
摘要： A storage and/or reaction container system for fluids, includes a container and an electronic documentation device connected to the container. The documentation device further includes a timing device for capturing a point in time, at least one sensor, at least one input device for capturing inputs, and a storage device to store for readout at least one measured value captured by the at least one sensor device and/or an input captured by the at least one input device. The at least one measured value and/or the at least one input is associated by the timing device with the point in time of the capture.
摘要翻译： 用于流体的储存和/或反应容器系统包括连接到容器的容器和电子文件装置。 文档装置还包括用于捕获时间点的定时装置，至少一个传感器，用于捕获输入的至少一个输入装置，以及用于存储用于读出由至少一个传感器装置捕获的至少一个测量值的存储装置 和/或由至少一个输入设备捕获的输入。 所述至少一个测量值和/或所述至少一个输入由所述定时装置与所述捕获的时间点相关联。
-
-
-
-
-
-
-
-
-
搜索结果
30 条记录 (耗时 0.022 秒)
