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公开(公告)号：US20110264190A1
公开(公告)日：2011-10-27
申请号：US13090525
申请日：2011-04-20
CPC分类号： A61L31/16 , A61L31/10 , A61L31/148 , A61L2300/30 , A61L2300/62 , A61L2420/02 , A61L2420/08 , C09D167/04
摘要： Provided herein are devices comprising a stent; and a coating on said stent comprising a polymer and an active agent, wherein the active agent comprises at least one of: extracellular matrix and an extracellular matrix component. Provided herein are methods of preparing a device comprising a stent and a coating on said stent; said method comprising: providing a stent; and forming a plurality of layers on said stent; wherein the coating comprises a polymer and at least one of said layers comprises one or more active agents; wherein at least a portion of the active agent comprises at least one of extracellular matrix and an extracellular matrix component.
摘要翻译： 本文提供了包括支架的装置; 以及所述支架上的包含聚合物和活性剂的涂层，其中所述活性剂包括细胞外基质和细胞外基质组分中的至少一种。 本文提供了制备包括支架和在所述支架上的涂层的装置的方法; 所述方法包括：提供支架; 并在所述支架上形成多个层; 其中所述涂层包含聚合物，并且所述层中的至少一个包含一种或多种活性剂; 其中所述活性剂的至少一部分包含细胞外基质和细胞外基质组分中的至少一种。
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公开(公告)号：US10232092B2
公开(公告)日：2019-03-19
申请号：US13090525
申请日：2011-04-20
IPC分类号： A61F2/82 , A61L31/16 , A61L31/10 , A61L31/14 , C09D167/04
摘要： Provided herein are devices comprising a stent; and a coating on said stent comprising a polymer and an active agent, wherein the active agent comprises at least one of: extracellular matrix and an extracellular matrix component. Provided herein are methods of preparing a device comprising a stent and a coating on said stent; said method comprising: providing a stent; and forming a plurality of layers on said stent; wherein the coating comprises a polymer and at least one of said layers comprises one or more active agents; wherein at least a portion of the active agent comprises at least one of extracellular matrix and an extracellular matrix component.
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