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公开(公告)号:US20090203757A1
公开(公告)日:2009-08-13
申请号:US12429107
申请日:2009-04-23
申请人: Ethan D. STERNBERG , David DOLPHIN , Julia G. LEVY , Anna M. RICHTER , David W.C. HUNT , Ashok JAIN , Elizabeth M. WATERFIELD , Ronald E. BOCH , Andrew Norman TOVEY
发明人: Ethan D. STERNBERG , David DOLPHIN , Julia G. LEVY , Anna M. RICHTER , David W.C. HUNT , Ashok JAIN , Elizabeth M. WATERFIELD , Ronald E. BOCH , Andrew Norman TOVEY
IPC分类号: A61K31/407 , A61P37/02
CPC分类号: C07D487/22 , A61K41/0071 , G06Q50/22 , Y10S514/825 , Y10S514/885
摘要: New compounds useful in photodynamic therapy are of the formula and their 1,4-diene isomers and the metallated and/or labeled and/or conjugated forms thereof wherein each R1 is independently alkyl (1-6C); each n is independently an integer of 0-6; and R2 is vinyl or a derivative form thereof.
摘要翻译: 可用于光动力学治疗的新化合物具有下式及其1,4-二烯异构体及其金属化和/或标记和/或共轭形式,其中每个R 1独立地为烷基(1-6C); 每个n独立地为0-6的整数; R2是乙烯基或其衍生形式。
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公开(公告)号:US20070191329A1
公开(公告)日:2007-08-16
申请号:US11524718
申请日:2006-09-20
申请人: Ethan Sternberg , David Dolphin , Julia Levy , Anna Richter , David Hunt , Ashok Jain , Elizabeth Waterfield , Ronald Boch , Andrew Tovey
发明人: Ethan Sternberg , David Dolphin , Julia Levy , Anna Richter , David Hunt , Ashok Jain , Elizabeth Waterfield , Ronald Boch , Andrew Tovey
IPC分类号: A61K31/555 , C07D487/22 , A61K31/409
CPC分类号: C07D487/22 , A61K41/0071 , G06Q50/22 , Y10S514/825 , Y10S514/885
摘要: New compounds useful in photodynamic therapy are of the formula and their 1,4-diene isomers and the metallated and/or labeled and/or conjugated forms thereof wherein each R1 is independently alkyl(1-6C); each n is independently an integer of 0-6; and R2 is vinyl or a derivative form thereof.
摘要翻译: 可用于光动力学治疗的新化合物具有下式及其1,4-二烯异构体及其金属化和/或标记和/或共轭形式,其中每个R 1独立地为烷基(1-6C) ; 每个n独立地为0-6的整数; R 2是乙烯基或其衍生形式。
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公开(公告)号:US07122569B2
公开(公告)日:2006-10-17
申请号:US10825270
申请日:2004-04-14
申请人: Ethan D. Sternberg , David Dolphin , Julia G. Levy , Anna M. Richter , David W. C. Hunt , Ashok Jain , Elizabeth M. Waterfield , Ronald E. Boch , Andrew Norman Tovey
发明人: Ethan D. Sternberg , David Dolphin , Julia G. Levy , Anna M. Richter , David W. C. Hunt , Ashok Jain , Elizabeth M. Waterfield , Ronald E. Boch , Andrew Norman Tovey
CPC分类号: C07D487/22 , A61K41/0071 , G06F19/00 , G06Q50/22 , Y10S514/825 , Y10S514/885
摘要: New compounds useful in photodynamic therapy are of the formula and their 1,4-diene isomers and the metallated and/or labeled and/or conjugated forms thereof wherein each R1 is independently alkyl (1–6C); each n is independently an integer of 0–6; and R2 is vinyl or a derivative form thereof.
摘要翻译: 可用于光动力学治疗的新化合物具有下式及其1,4-二烯异构体及其金属化和/或标记和/或共轭形式,其中每个R 1独立地为烷基(1-6C) ; 每个n独立地为0-6的整数; R 2是乙烯基或其衍生形式。
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公开(公告)号:US06756396B1
公开(公告)日:2004-06-29
申请号:US09588206
申请日:2000-06-06
申请人: Ethan Sternberg , David Dolphin , Julia G. Levy , Anna M. Richter , David W. C. Hunt , Ashok Jain , Elizabeth M. Waterfield , Ronald E. Boch
发明人: Ethan Sternberg , David Dolphin , Julia G. Levy , Anna M. Richter , David W. C. Hunt , Ashok Jain , Elizabeth M. Waterfield , Ronald E. Boch
IPC分类号: A61K3140
CPC分类号: C07D487/22 , A61K41/0071 , G06F19/00 , G06Q50/22 , Y10S514/825 , Y10S514/885
摘要: New compounds useful in photodynamic therapy are of the formula and their 1,4-diene isomers and the metallated and/or labeled and/or conjugated forms thereof wherein each R1 is independently alkyl (1-6C); each n is independently an integer of 0-6; and R2 is vinyl or a derivative form thereof.
摘要翻译: 可用于光动力学治疗的新化合物具有式及其1,4-二烯异构体及其金属化和/或标记和/或共轭形式,其中R 1独立地为烷基(1-6C);各n独立地为整数 0-6; 和R 2是乙烯基或其衍生形式。
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公开(公告)号:US5929105A
公开(公告)日:1999-07-27
申请号:US088524
申请日:1998-06-01
申请人: Ethan Sternberg , David Dolphin , Julia G. Levy , Anna M. Richter , David W. C. Hunt , Ashok Jain
发明人: Ethan Sternberg , David Dolphin , Julia G. Levy , Anna M. Richter , David W. C. Hunt , Ashok Jain
IPC分类号: A61K31/409 , A61K41/00 , A61K49/00 , A61P35/00 , C07D487/22 , A61K31/40
CPC分类号: C07D487/22 , A61K41/0071
摘要: New compounds useful in photodynamic therapy are of the formula ##STR1## and their 1,4-diene isomers and the metallated and/or labeled and/or conjugated forms thereofwherein each R.sup.1 is independently alkyl (1-6C);each n is independently an integer of 0-6; andR.sup.2 is vinyl or a derivative form thereof.
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公开(公告)号:US20070197792A1
公开(公告)日:2007-08-23
申请号:US11349461
申请日:2006-02-07
IPC分类号: C07D403/02
CPC分类号: C07D401/06
摘要: A process for the preparation of the insecticide imidacloprid includes the reaction of 2-chloro-5-chloromethyl pyridine with 2-nitroiminoimidazolidine, carried out in the molar ratio of 1:1 to 1:1.2, in the presence of an alkali metal hydroxide in an aprotic solvent at 45 to 60° C. under stirring.
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公开(公告)号:US20050032769A1
公开(公告)日:2005-02-10
申请号:US10825270
申请日:2004-04-14
申请人: Ethan Sternberg , David Dolphin , Julia Levy , Anna Richter , David Hunt , Ashok Jain , Elizabeth Waterfield , Ronald Boch , Andrew Tovey
发明人: Ethan Sternberg , David Dolphin , Julia Levy , Anna Richter , David Hunt , Ashok Jain , Elizabeth Waterfield , Ronald Boch , Andrew Tovey
IPC分类号: A61K41/00 , C07D487/22 , A61K31/409 , A61K31/555
CPC分类号: C07D487/22 , A61K41/0071 , G06F19/00 , G06Q50/22 , Y10S514/825 , Y10S514/885
摘要: New compounds useful in photodynamic therapy are of the formula and their 1,4-diene isomers and the metallated and/or labeled and/or conjugated forms thereof wherein each R1 is independently alkyl (1-6C); each n is independently an integer of 0-6; and R2 is vinyl or a derivative form thereof.
摘要翻译: 可用于光动力学治疗的新化合物具有下式及其1,4-二烯异构体及其金属化和/或标记和/或共轭形式,其中每个R 1独立地为烷基(1-6C); 每个n独立地为0-6的整数; R 2是乙烯基或其衍生形式。
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公开(公告)号:US6153639A
公开(公告)日:2000-11-28
申请号:US313106
申请日:1999-05-17
申请人: Ethan Sternberg , David Dolphin , Julia G. Levy , Anna M. Richter , David W. C. Hunt , Ashok Jain , Elizabeth M. Waterfield , Ronald E. Boch
发明人: Ethan Sternberg , David Dolphin , Julia G. Levy , Anna M. Richter , David W. C. Hunt , Ashok Jain , Elizabeth M. Waterfield , Ronald E. Boch
IPC分类号: A61K31/409 , A61K41/00 , A61K49/00 , A61P35/00 , C07D487/22 , A61K31/40
CPC分类号: C07D487/22 , A61K41/0071
摘要: New compounds useful in photodynamic therapy are of the formula ##STR1## and their 1,4-diene isomers and the metallated and/or labeled and/or conjugated forms thereofwherein each R.sup.1 is independently alkyl (1-6C);each n is independently an integer of 0-6; andR.sup.2 is vinyl or a derivative form thereof.
摘要翻译: 可用于光动力学治疗的新化合物具有下式及其1,4-二烯异构体及其金属化和/或标记和/或共轭形式,其中每个R 1独立地为烷基(1-6C); 每个n独立地为0-6的整数; R2是乙烯基或其衍生形式。
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