公开(公告)号：US20210180035A1

公开(公告)日：2021-06-17

申请号：US17125480

申请日：2020-12-17

Applicant: Stuart Kornfeld ,  Lin Liu ,  Wang Lee ,  Balraj Doray

Inventor： Stuart Kornfeld ,  Lin Liu ,  Wang Lee ,  Balraj Doray

IPC: C12N9/12 ,  C12N9/24

Abstract: The disclosure provides a modified UDP-GlcNAc:Lysosomal Enzyme GlcNAc-1-phosphotransferase with enhanced ability to phosphorylate lysosomal enzymes and methods of use thereof.

公开(公告)号：US10907139B2

公开(公告)日：2021-02-02

申请号：US16338347

申请日：2017-10-02

Applicant: Stuart A. Kornfeld ,  Balraj Doray ,  Wang Lee ,  Lin Liu

Inventor： Stuart A. Kornfeld ,  Balraj Doray ,  Wang Lee ,  Lin Liu

IPC: C12N9/10 ,  A61K38/04 ,  C12N9/12 ,  C12N9/24

Abstract: The disclosure provides a modified UDP-GlcNAc:Lysosomal Enzyme GlcNAc-1-phosphotransferase with enhanced ability to phosphorylate lysosomal enzymes and methods of use thereof.