公开(公告)号：US20130156832A1

公开(公告)日：2013-06-20

申请号：US13702250

申请日：2011-07-12

申请人： Barbara Onida ,  Renato Silvio Mortera

发明人： Barbara Onida ,  Renato Silvio Mortera

IPC分类号： A61K9/00

CPC分类号： A61K9/0014 ,  A61K8/0208 ,  A61K8/25 ,  A61K8/368 ,  A61K9/06 ,  A61K9/5115 ,  A61K31/60 ,  A61K47/02 ,  A61K47/186 ,  A61K47/44 ,  A61K2800/413 ,  A61Q19/00 ,  B82Y5/00 ,  Y10S977/814 ,  Y10S977/906

摘要： Eudermic composition comprising at least one eudermically active principle, at least one vehicle for said active principle, and porous silica particles, wherein the active principle is contained in at least one pore of at least a first portion of such silica particles and in the vehicle.

摘要翻译： 包含至少一种用于所述活性成分的至少一种营养学原理的尿液组合物和所述活性成分的多孔二氧化硅颗粒，其中所述活性成分包含在所述二氧化硅颗粒的至少第一部分的至少一个孔中和所述载体中。

公开(公告)号：US20130059013A1

公开(公告)日：2013-03-07

申请号：US13697076

申请日：2011-05-12

申请人： Chiara Vitale Brovarone ,  Enrica Verne' ,  Mauro Bergui ,  Barbara Onida ,  Francesco Baino ,  Marta Miola ,  Sara Ferraris ,  Francesca Tallia

发明人： Chiara Vitale Brovarone ,  Enrica Verne' ,  Mauro Bergui ,  Barbara Onida ,  Francesco Baino ,  Marta Miola ,  Sara Ferraris ,  Francesca Tallia

IPC分类号： A61K33/42 ,  A61P19/08

CPC分类号： A61L24/0068 ,  A61L24/0063 ,  A61L27/425 ,  A61L27/427 ,  A61L27/50 ,  A61L27/54 ,  A61L2300/44 ,  A61L2400/06 ,  A61L2430/02

摘要： An injectable composition for bone filling or consolidation, for use in surgery or therapy, characterized in that it comprises a biocompatible powdery material, which is hardenable or cross-linkable and selected from calcium sulphate hemi-hydrate and polymethylmethacrylate, a hardening or cross-linking agent for said material and a porous silica-based powdery material, having a specific surface area higher than 100 m2/g, which comprises a mesoporous bioactive glass, obtainable/achievable by a sol-gel method with the addition of a surfactant as structure-directing agent for pores formation, comprising an oxide mixture containing:SiO2: from 60 to 85% by moles CaO: from 10 to 30% by moles P2O5: from 2 to 10% by moles said composition, when applied to an affected area of a patient, being adapted to form a composite material wherein said hardenable or cross-linkable material constitutes a matrix and said mesoporous bioactive glass constitutes a dispersed phase in said matrix.

摘要翻译： 一种用于手术或治疗的用于骨填充或固结的可注射组合物，其特征在于其包含可硬化或可交联并且选自硫酸钙半水合物和聚甲基丙烯酸甲酯的生物相容性粉末材料，硬化或交联 所述材料的试剂和比表面积高于100m 2 / g的多孔二氧化硅基粉末材料，其包含可通过溶胶 - 凝胶法获得/可实现的介孔生物活性玻璃，通过添加表面活性剂作为结构 - 包含氧化物混合物，其包含：SiO 2：60至85摩尔％CaO：10至30摩尔％P 2 O 5：所述组合物的2至10摩尔％当施用于 患者，适于形成复合材料，其中所述可硬化或可交联材料构成基质，所述介孔生物活性玻璃在所述基质中构成分散相。