公开(公告)号：US20130059013A1

公开(公告)日：2013-03-07

申请号：US13697076

申请日：2011-05-12

申请人： Chiara Vitale Brovarone ,  Enrica Verne' ,  Mauro Bergui ,  Barbara Onida ,  Francesco Baino ,  Marta Miola ,  Sara Ferraris ,  Francesca Tallia

发明人： Chiara Vitale Brovarone ,  Enrica Verne' ,  Mauro Bergui ,  Barbara Onida ,  Francesco Baino ,  Marta Miola ,  Sara Ferraris ,  Francesca Tallia

IPC分类号： A61K33/42 ,  A61P19/08

CPC分类号： A61L24/0068 ,  A61L24/0063 ,  A61L27/425 ,  A61L27/427 ,  A61L27/50 ,  A61L27/54 ,  A61L2300/44 ,  A61L2400/06 ,  A61L2430/02

摘要： An injectable composition for bone filling or consolidation, for use in surgery or therapy, characterized in that it comprises a biocompatible powdery material, which is hardenable or cross-linkable and selected from calcium sulphate hemi-hydrate and polymethylmethacrylate, a hardening or cross-linking agent for said material and a porous silica-based powdery material, having a specific surface area higher than 100 m2/g, which comprises a mesoporous bioactive glass, obtainable/achievable by a sol-gel method with the addition of a surfactant as structure-directing agent for pores formation, comprising an oxide mixture containing:SiO2: from 60 to 85% by moles CaO: from 10 to 30% by moles P2O5: from 2 to 10% by moles said composition, when applied to an affected area of a patient, being adapted to form a composite material wherein said hardenable or cross-linkable material constitutes a matrix and said mesoporous bioactive glass constitutes a dispersed phase in said matrix.

摘要翻译： 一种用于手术或治疗的用于骨填充或固结的可注射组合物，其特征在于其包含可硬化或可交联并且选自硫酸钙半水合物和聚甲基丙烯酸甲酯的生物相容性粉末材料，硬化或交联 所述材料的试剂和比表面积高于100m 2 / g的多孔二氧化硅基粉末材料，其包含可通过溶胶 - 凝胶法获得/可实现的介孔生物活性玻璃，通过添加表面活性剂作为结构 - 包含氧化物混合物，其包含：SiO 2：60至85摩尔％CaO：10至30摩尔％P 2 O 5：所述组合物的2至10摩尔％当施用于 患者，适于形成复合材料，其中所述可硬化或可交联材料构成基质，所述介孔生物活性玻璃在所述基质中构成分散相。

公开(公告)号：US20100179662A1

公开(公告)日：2010-07-15

申请号：US12602324

申请日：2008-05-28

申请人： Enrica Verne ,  Chiara Vitale Brovarone ,  Lorenza Robiglio ,  Francesco Baino

发明人： Enrica Verne ,  Chiara Vitale Brovarone ,  Lorenza Robiglio ,  Francesco Baino

IPC分类号： A61F2/38 ,  A61F2/32

CPC分类号： A61L27/306 ,  A61F2/30767 ,  A61F2/3094 ,  A61F2/34 ,  A61F2/38 ,  A61F2002/30706 ,  A61F2002/3092 ,  A61F2002/30929 ,  A61F2002/30968 ,  A61F2002/3446 ,  A61F2250/0082 ,  A61F2310/00203 ,  A61F2310/00239 ,  A61F2310/00592 ,  A61F2310/00928 ,  A61L27/10 ,  A61L27/56 ,  C03C3/062 ,  C03C3/097 ,  C03C4/0007 ,  C03C8/08 ,  C03C10/00 ,  C03C14/004 ,  C03C2214/20

摘要： Single-piece prosthesis elements chosen from among acetabular cup for hip prosthesis, tibial component and femoral component for knee prosthesis, comprising a body (2) of ceramic material or ceramic matrix composite material, a bioactive porous coating (4) of glass material, glass-ceramic material or glass-ceramic matrix material applied to the surface of said body intended for anchoring with the bone tissue, where said bioactive porous coating (4) is anchored to the body surface (2) by means of a glass or glass-ceramic phase layer.

摘要翻译： 从用于髋关节假体的髋臼杯，膝关节假体的胫骨部件和股骨部件中选择的单件假体元件，包括陶瓷材料或陶瓷基体复合材料的主体（2），玻璃材料的生物活性多孔涂层（4），玻璃 - 陶瓷材料或玻璃 - 陶瓷基体材料，其施加到所述主体的表面以用于与骨组织锚固，其中所述生物活性多孔涂层（4）通过玻璃或玻璃陶瓷锚固到身体表面（2） 相层。