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1.发明申请METHODS AND REAGENTS FOR THE DIAGNOSIS, PREVENTION AND TREATMENT OF INSULIN RESISTANCE 有权诊断，预防和治疗胰岛素抵抗的方法和试剂公开(公告)号：US20110245145A1
公开(公告)日：2011-10-06
申请号：US13132750
申请日：2009-12-03
IPC分类号： A61K38/02 , C12N15/63 , C07K14/47 , G01N33/566 , C12Q1/68 , A61K31/7088 , C07K16/18 , C07H21/00 , A61P3/10 , A61P3/08 , A61P3/04 , A61P9/12 , A61P9/00 , A61P19/06
CPC分类号： A61K38/1709
摘要： The present invention provides the use of βarrestin2 protein or its up-regulators for manufacturing a composition for the prevention or treatment of insulin resistance or related disease in mammals. The reagents and the kits for the specific identification of βarrestin2 protein or its coding gene or transcript are also provided which can be used in diagnosis of insulin resistance or related diseases.
摘要翻译： 本发明提供了用于制备用于预防或治疗哺乳动物的胰岛素抵抗或相关疾病的组合物的抑制蛋白2或其上调节剂的用途。 还提供了用于特异性鉴定和抑制蛋白2或其编码基因或转录物的试剂和试剂盒，其可用于胰岛素抵抗或相关疾病的诊断。
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2.发明授权Methods and reagents for the diagnosis, prevention and treatment of insulin resistance using beta-arrestin2 and its up-regulators 有权使用β-arrestin2及其上调的诊断，预防和治疗胰岛素抵抗的方法和试剂公开(公告)号：US08536121B2
公开(公告)日：2013-09-17
申请号：US13132750
申请日：2009-12-03
CPC分类号： A61K38/1709
摘要： The present invention provides the use of βarrestin2 protein or its up-regulators for manufacturing a composition for the prevention or treatment of insulin resistance or related disease in mammals. The reagents and the kits for the specific identification of βarrestin2 protein or its coding gene or transcript are also provided which can be used in diagnosis of insulin resistance or related diseases.
摘要翻译： 本发明提供了βarrestin2蛋白或其上调体用于制备用于预防或治疗哺乳动物中的胰岛素抵抗或相关疾病的组合物的用途。 还提供了用于特异性鉴定βarrestin2蛋白或其编码基因或转录物的试剂和试剂盒，可用于胰岛素抵抗或相关疾病的诊断。
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