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公开(公告)号：US20060199810A1
公开(公告)日：2006-09-07
申请号：US11417867
申请日：2006-05-03
IPC分类号： A61K31/5415 , A61K31/538 , A61K31/4709 , C07D417/02 , C07D401/02 , C07D413/02
CPC分类号： C07D451/02 , C07D401/04 , C07D413/06 , C07D417/06 , C07D513/04
摘要： The present invention relates to tetrahydroquinoline compounds as muscarinic receptor agonists; compositions comprising the same; methods of inhibiting an activity of a muscarinic receptor with said compounds; methods of treating a disease condition associated with a muscarinic receptor using said compounds; and methods for identifying a subject suitable for treatment using said compounds.
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公开(公告)号：US20060199813A1
公开(公告)日：2006-09-07
申请号：US11417865
申请日：2006-05-03
IPC分类号： A61K31/5415 , A61K31/538 , C07D417/02 , C07D413/02
CPC分类号： C07D451/02 , C07D401/04 , C07D413/06 , C07D417/06 , C07D513/04
摘要： The present invention relates to tetrahydroquinoline compounds as muscarinic receptor agonists; compositions comprising the same; methods of inhibiting an activity of a muscarinic receptor with said compounds; methods of treating a disease condition associated with a muscarinic receptor using said compounds; and methods for identifying a subject suitable for treatment using said compounds.
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公开(公告)号：US20070155795A1
公开(公告)日：2007-07-05
申请号：US11676178
申请日：2007-02-16
IPC分类号： A61K31/454 , A61K31/453 , A61K31/452 , C07D409/02 , C07D405/02 , C07D403/02
CPC分类号： C07D401/06 , C07D405/06 , C07D409/06 , C07D413/06 , C07D413/12 , C07D417/06 , C07D471/04 , C07D473/00 , C07D487/04
摘要： Compounds and methods are provided for the treatment of disease conditions in which modification of cholinergic, especially muscarinic m1, m4, or both m1 and m4, receptor activity has a beneficial effect. In the method, an effective amount of a compound is administered to a patient in need of such treatment.
摘要翻译： 提供化合物和方法用于治疗胆碱能，特别是毒蕈碱m1，m4或m1和m4两者受体活性的改变具有有益效果的疾病状况。 在该方法中，向需要这种治疗的患者施用有效量的化合物。
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