公开(公告)号：US5661006A

公开(公告)日：1997-08-26

申请号：US308872

申请日：1994-09-19

Applicant: Thomas David Kay Brown ,  Brian Colin Horsburgh

Inventor： Thomas David Kay Brown ,  Brian Colin Horsburgh

IPC: A61K39/00 ,  A61K39/215 ,  A61P31/12 ,  C07K14/165 ,  C12N5/10 ,  C12N7/00 ,  C12N15/09 ,  C12N15/50 ,  C12N15/86 ,  C12N15/863 ,  C12P21/02 ,  C12R1/91 ,  C12R1/92 ,  C07H21/00 ,  C12N15/06 ,  C12N15/63

CPC classification number: C07K14/005 ,  C12N15/86 ,  A61K39/00 ,  C12N2710/24143 ,  C12N2770/20022

Abstract: The invention is related to a nucleic acid sequence &coding a Canine coronavirus (CCV) spike protein. Such a protein can be used for the immunization of dogs against CCV infection. The nucleic acid sequence encoding the CCV spike protein can be applied for the preparation of the spike protein by means of genetic engineering techniques or can be applied for the preparation of vector vaccines.

Abstract translation: 本发明涉及编码犬冠状病毒（CCV）刺突蛋白的核酸序列。 这样的蛋白质可以用于狗免疫CCV感染。 编码CCV尖峰蛋白的核酸序列可以通过基因工程技术应用于尖峰蛋白的制备，或者可以用于制备载体疫苗。