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公开(公告)号:US08491872B2
公开(公告)日:2013-07-23
申请号:US13057374
申请日:2009-08-04
申请人: Umesh R. Desai , Brian L. Henry , Aiye Liang , Jay Thakkar , John B. Mangrum , Ivo Torres Filho , Bruce D. Spiess , Masahiro Sakagami , Bhawana Saluja
发明人: Umesh R. Desai , Brian L. Henry , Aiye Liang , Jay Thakkar , John B. Mangrum , Ivo Torres Filho , Bruce D. Spiess , Masahiro Sakagami , Bhawana Saluja
IPC分类号: A61P7/02 , A61P29/00 , A61P11/00 , A61K31/185 , A61K31/343 , A61K31/255 , C07C305/24 , C07D307/80 , C07D307/84 , C07D407/14
CPC分类号: C07D407/14 , A61K9/007 , A61K31/185 , A61K31/192 , A61K31/343 , C07C305/24 , C07D307/80 , C07D307/84
摘要: Cinnamic acid-based oligomers and therapeutic uses thereof are provided. The oligomers are used as anti-inflammation agents, inhibitors of elastase and anti-oxidants, and in some cases (e.g. the treatment of lung disorders such as lung cancer) all three activities are simultaneously beneficial. Subsets of the oligomers (e.g. β-O4 and β-5 trimers and tetramers) are used as anticoagulants.
摘要翻译: 提供肉桂酸类低聚物及其治疗用途。 低聚物用作抗炎剂,弹性蛋白酶和抗氧化剂的抑制剂,并且在一些情况下(例如治疗肺部疾病如肺癌),所有这三种活性同时是有益的。 寡聚体(例如β-O4和β-5三聚体和四聚体)的亚类被用作抗凝剂。
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公开(公告)号:US20120027691A1
公开(公告)日:2012-02-02
申请号:US13057374
申请日:2009-08-04
申请人: Umesh R. Desai , Brian L. Henry , Aiye Liang , Jay Thakkar , John B. Mangrum , Ivo Torres Filho , Bruce D. Spiess , Masahiro Sakagami , Bhawana Saluja
发明人: Umesh R. Desai , Brian L. Henry , Aiye Liang , Jay Thakkar , John B. Mangrum , Ivo Torres Filho , Bruce D. Spiess , Masahiro Sakagami , Bhawana Saluja
IPC分类号: A61K31/255 , C07D407/14 , A61K9/12 , A61P7/02 , A61P29/00 , A61P11/00 , C07C305/24 , A61K31/343
CPC分类号: C07D407/14 , A61K9/007 , A61K31/185 , A61K31/192 , A61K31/343 , C07C305/24 , C07D307/80 , C07D307/84
摘要: Cinnamic acid-based oligomers and therapeutic uses thereof are provided. The oligomers are used as anti-inflammation agents, inhibitors of elastase and anti-oxidants, and in some cases (e.g. the treatment of lung disorders such as lung cancer) all three activities are simultaneously beneficial. Subsets of the oligomers (e.g. β-O4 and β-5 trimers and tetramers) are used as anticoagulants.
摘要翻译: 提供肉桂酸类低聚物及其治疗用途。 低聚物用作抗炎剂,弹性蛋白酶和抗氧化剂的抑制剂,并且在一些情况下(例如治疗肺部疾病如肺癌),所有这三种活性同时是有益的。 低聚物(例如&bgr; -O4和&bgr; -5 +三聚体和四聚体)的亚类被用作抗凝剂。
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公开(公告)号:US07761578B2
公开(公告)日:2010-07-20
申请号:US11413868
申请日:2006-04-28
IPC分类号: G06F15/16
CPC分类号: G06F9/5077 , H04L69/16 , H04L69/161 , H04L69/32
摘要: A computer system and method for communicating in a virtual environment. The computer system may include a first partition and a virtual service client implemented at a first position in the first partition. The computer system may also include a second partition, and a virtual service provider implemented at a second position in the second partition. The first partition and the second partition may be in operative communication via the virtual service client and the virtual service provider. The first position and the second position may enable the virtual service client and the virtual service provider to reduce processing overhead associated with communicating in the virtual environment by eliminating a processing step, a buffer copy, a software interrupt, and/or a context switch.
摘要翻译: 一种用于在虚拟环境中通信的计算机系统和方法。 计算机系统可以包括在第一分区中的第一位置处实现的第一分区和虚拟服务客户端。 计算机系统还可以包括在第二分区中的第二位置处实现的第二分区和虚拟服务提供商。 第一分区和第二分区可以经由虚拟服务客户端和虚拟服务提供商进行操作性通信。 第一位置和第二位置可以使虚拟服务客户端和虚拟服务提供商能够通过消除处理步骤,缓冲器拷贝,软件中断和/或上下文切换来减少与虚拟环境中的通信相关联的处理开销。
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